{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:08:46Z","timestamp":1792804126050,"version":"4.5.0"},"reference-count":6,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic liver disease is characterized by lowered immunity, altered hematological parameters, and poor wound healing. Surgeons may hesitate to intervene in such patients when they present with necrotizing fasciitis (NF) or misinform the patients regarding their chances of survival. This is because of the poor nutritional state, thrombocytopaenia, and abnormal coagulation profile. However, recent guidelines show that platelet count and prothrombin time\/international normalized ratio (PT-INR) do not predict postoperative bleeding. We can proceed with debridement followed by skin grafting of wounds in such patients. This will help reduce the high mortality rate of NF in cirrhotic patients.<\/jats:p>","DOI":"10.1055\/s-0043-1773770","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T23:01:51Z","timestamp":1695769311000},"page":"466-469","source":"Crossref","is-referenced-by-count":1,"title":["Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease"],"prefix":"10.1055","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6604-6480","authenticated-orcid":false,"given":"M.","family":"Choundappan","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Tirunelveli Medical College, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jpge.2015.06.004","article-title":"Nutrition in chronic liver disease","volume":"22","author":"M Silva","year":"2015","journal-title":"GE Port J Gastroenterol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"7537649","DOI":"10.1155\/2019\/7537649","article-title":"Immune dysfunction and albumin-related immunity in liver cirrhosis","volume":"2019","author":"B Wilde","year":"2019","journal-title":"Mediators Inflamm"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1053\/j.gastro.2021.08.015","article-title":"AGA clinical practice guideline on the management of coagulation disorders in patients with cirrhosis","volume":"161","author":"R S O'Shea","year":"2021","journal-title":"Gastroenterology"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.jhep.2021.09.003","article-title":"EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis","volume":"76","author":"European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu","year":"2022","journal-title":"J Hepatol"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4103\/0970-0358.59281","article-title":"Evaluation of skin graft take following post-burn raw area in normovolaemic anaemia","volume":"42","author":"P Agarwal","year":"2009","journal-title":"Indian J Plast Surg"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"562","DOI":"10.22271\/ortho.2017.v3.i4h.78","article-title":"A retrospective study of effect of anaemia on split thickness skin graft uptake in orthopaedic trauma cases","volume":"3","author":"A R Kale","year":"2017","journal-title":"International Journal of Orthopaedics Sciences"}],"container-title":["Indian Journal of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0043-1773770.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T23:34:04Z","timestamp":1700609644000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0043-1773770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":6,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2023,11,21]]},"published-print":{"date-parts":[[2023,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0043-1773770","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0970-0358","1998-376X"],"issn-type":[{"value":"0970-0358","type":"print"},{"value":"1998-376X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,26]]}}}