{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:33:16Z","timestamp":1740126796521,"version":"3.37.3"},"reference-count":35,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropediatrics"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Attention deficit hyperactivity disorder (ADHD) is a common neuropsychological disorder primarily diagnosed in childhood. Early intervention was found to significantly improve developmental outcomes, implicating on the role of early identification of ADHD markers. In the current study, we explored the developmental history of children referred to neurological assessment to identify early ADHD predictors.<\/jats:p><jats:p>\n          Methods\u2003A total of 92 children and adolescents (41 females) recruited at a pediatric neurology clinic, with suspected ADHD (n\u2009=\u200939) or other neurological difficulties (n\u2009=\u200953) such as headaches, seizures, tic disorders, orthostatic hypotension, postischemic stroke, intermittent pain, and vasovagal syncope. Developmental history information was obtained from caregivers, and evaluation for possible ADHD was performed. Developmental details were compared between children with and without current ADHD diagnosis.<\/jats:p><jats:p>\n          Results\u2003Word-finding difficulties (WFDs) in preschool age was reported in 30.4% of the sample. Among children diagnosed with ADHD, 43% had WFDs history, compared with only 5% in children without ADHD. Among children with WFDs history, 93% were later diagnosed with ADHD compared with 42% in children without WFDs history. The relationship between WFDs and ADHD was significant (chi-square test [1, N\u2009=\u200992]\u2009=\u200920.478, p\u2009&lt;\u20090.0001), and a logistic regression model demonstrated that asides from a family history of ADHD, the strongest predictor for ADHD in school age children was a history of WFDs.<\/jats:p><jats:p>\n          Conclusion\u2003Preliminary evidence supports a predictive link between preschool WFDs and later ADHD diagnosis, highlighting the importance of early WFDs clinical attention.<\/jats:p>","DOI":"10.1055\/s-0043-1776356","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T23:59:10Z","timestamp":1701302350000},"page":"049-056","source":"Crossref","is-referenced-by-count":0,"title":["Word-Finding Difficulties as a Prominent Early Finding in a Later Diagnosis of Attention Deficit Hyperactivity Disorder"],"prefix":"10.1055","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4802-5832","authenticated-orcid":false,"given":"Esther","family":"Ganelin-Cohen","sequence":"additional","affiliation":[{"name":"Institute of Pediatric Neurology, Schneider Children's Medical Center of Israel, Petach Tikvah, Israel"},{"name":"Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tammy","family":"Pilowsky Peleg","sequence":"additional","affiliation":[{"name":"Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel"},{"name":"Neuropsychological Unit, Schneider Children's Medical Center of Israel, Petach Tikvah, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noa","family":"Leibovich","sequence":"additional","affiliation":[{"name":"Institute of Pediatric Neurology, Schneider Children's Medical Center of Israel, Petach Tikvah, Israel"},{"name":"Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Bachrachg","sequence":"additional","affiliation":[{"name":"Department of Psychology, The Hebrew University of Jerusalem, Jerusalem, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Watemberg","sequence":"additional","affiliation":[{"name":"Child Neurology Unit, Meir Medical Center, Kfar Saba, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1177\/1087054719886372","article-title":"Prevalence of ADHD and its comorbidities in a population-based sample","volume":"25","author":"M R Mohammadi","year":"2021","journal-title":"J Atten Disord"},{"volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"2022","edition":"5th ed. 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G\u00f6z\u00fcm","year":"2021","journal-title":"Curr Psychol"},{"issue":"04","key":"ref20","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1044\/2014_JSLHR-L-12-0411","article-title":"Associations between toddler-age communication and kindergarten-age self-regulatory skills","volume":"57","author":"T Aro","year":"2014","journal-title":"J Speech Lang Hear Res"},{"issue":"04","key":"ref21","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00004703-199708000-00009","article-title":"Attention-deficit\/hyperactivity disorder, self-regulation, and time: toward a more comprehensive theory","volume":"18","author":"R A Barkley","year":"1997","journal-title":"J Dev Behav Pediatr"},{"issue":"01","key":"ref22","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1186\/s12888-016-1091-3","article-title":"Relationship between early language skills and the development of inattention\/hyperactivity symptoms during the preschool period: results of the EDEN mother-child 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Brites","year":"2021"},{"issue":"04","key":"ref26","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1080\/136828298247721","article-title":"Children with word-finding difficulties\u2013prevalence, presentation and naming problems","volume":"33","author":"J E Dockrell","year":"1998","journal-title":"Int J Lang Commun Disord"},{"volume-title":"Attention Deficit Hyperactivity Disorder: Diagnosis and Management","year":"2018","author":"National Guideline Centre (UK)","key":"ref27"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013","edition":"5th ed."},{"issue":"04","key":"ref29","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1177\/1359104519846602","article-title":"The Conners 3-short forms: Evaluating the adequacy of brief versions to assess ADHD symptoms and related problems","volume":"24","author":"V A Izzo","year":"2019","journal-title":"Clin Child Psychol Psychiatry"},{"issue":"04","key":"ref30","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/s41380-018-0070-0","article-title":"Genetics of attention deficit hyperactivity disorder","volume":"24","author":"S V Faraone","year":"2019","journal-title":"Mol Psychiatry"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00001163-199704000-00005","article-title":"The impact of sensory processing abilities on the daily lives of young children and their families: a conceptual model","volume":"9","author":"W Dunn","year":"1997","journal-title":"Infants Young Child"},{"issue":"06","key":"ref32","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1017\/S0012162204000623","article-title":"Relationship between motor proficiency, attention, impulse, and activity in children with ADHD","volume":"46","author":"M H Tseng","year":"2004","journal-title":"Dev Med 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