{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T11:49:52Z","timestamp":1753357792513,"version":"3.37.3"},"reference-count":16,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":35,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n               Introduction\u2003Some common symptoms of coronavirus disease 2019 (COVID-19) are fever, cough, and shortness of breath. But ear, nose, and throat (ENT) manifestations such as loss of smell and taste are also very common.<\/jats:p><jats:p>\n               Objectives\u2003To compare the general and otorhinolaryngological manifestations of COVID-19 and to compare the treatments given and mortality rate during its two waves.<\/jats:p><jats:p>\n               Methods\u2003This retrospective study was conducted on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases in a tertiary care teaching hospital. Six hundred patients were included in the 1st wave sample and 516 were in the 2nd wave sample. The data collected included demographics, comorbidities, general, and ENT symptoms, need for ventilatory support, oxygen therapy, and mortality for both the waves.<\/jats:p><jats:p>\n               Results\u2003Fever, malaise, and myalgia were more frequently presented in the first wave than in the second, whereas shortness of breath was more common in the second wave. In the second wave, a significant increase in anosmia cases was reported, whereas sore throat, nasal obstruction, dysphagia, nasal discharge, and sneezing were significantly reduced compared with the first wave (p\u2009&lt;\u20090.001). The case fatality rate increased from 11.33 to 21.55% (p\u2009&lt;\u20090.001) from the 1st to the 2nd wave. The patients who died in the second wave were younger than those in the first wave. Two doses of vaccination showed protection from the death over those not vaccinated and those who only received one dose (p\u2009&lt;\u20090.05).<\/jats:p><jats:p>\n               Conclusion\u2003Ear, nose, and throat (ENT) manifestations are very common along with the general symptoms. As anosmia and dysgeusia are early presenting symptoms in COVID-19 patients, all physicians should screen patients for ENT symptoms.<\/jats:p>","DOI":"10.1055\/s-0043-1777419","type":"journal-article","created":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:31:51Z","timestamp":1707179511000},"page":"e3-e11","source":"Crossref","is-referenced-by-count":1,"title":["A Comparative Study on the General and Otolaryngological Manifestations of COVID-19 in the Hospitalized Population of the Telangana Region During the First and Second Waves"],"prefix":"10.1055","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6112-0987","authenticated-orcid":false,"given":"Uma","family":"Pokala","sequence":"additional","affiliation":[{"name":"Department of ENT, Mamata Medical College, Khammam, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2283-4607","authenticated-orcid":false,"given":"Shilpa","family":"Potnuru","sequence":"additional","affiliation":[{"name":"Department of ENT, NRI Institute of Medical Sciences, Vizag, AP, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9712-4664","authenticated-orcid":false,"given":"Sasikala","family":"Kanapalli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Vishwabharathi Medical College, Kurnool, Andhra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0694-8014","authenticated-orcid":false,"given":"Agni Vishnu","family":"Sailesh","sequence":"additional","affiliation":[{"name":"Department of ENT, Mamata Medical College, Khammam, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7748-5892","authenticated-orcid":false,"given":"Naveen","family":"P.","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Mamata Medical College, Khammam, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,5]]},"reference":[{"volume-title":"Features, Evaluation, and Treatment of Coronavirus (COVID-19). 2022 May 4","author":"M Cascella","key":"ref1"},{"issue":"01","key":"ref2","first-page":"157","article-title":"WHO Declares COVID-19 a Pandemic","volume":"91","author":"D Cucinotta","year":"2020","journal-title":"Acta Biomed"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"102581","DOI":"10.1016\/j.amjoto.2020.102581","article-title":"COVID-19 and anosmia: A review based on up-to-date knowledge","volume":"41","author":"X Meng","year":"2020","journal-title":"Am J 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