{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T16:29:39Z","timestamp":1772123379033,"version":"3.50.1"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003This study investigates the correlation of the radiologic sign of interhemispheric subdural hematoma (iSDH) in different injury patterns with clinical coagulation disorders. It is hypothesized that the presence of iSDHs is correlated with clinical coagulation disorders in patients with traumatic brain injuries and subdural hematoma (SDH).<\/jats:p><jats:p>\n          Methods\u2003Between January 1, 2020 and June 30, 2022, 154 patients with SDH were identified. Coagulation disorders were assessed using chart review and patients were divided into four groups: SDH without iSDH without further injuries (SDH), SDH with iSDH without further injuries (SDH\u2009+\u2009iSDH), SDH without iSDH with further brain injuries (Combi), SDH with iSDH with further injuries (Combi\u2009+\u2009iSDH). These four groups were formed under the assumption that isolated SDHs result from a highly specific trauma mechanism (rupture of bridging veins) in predisposed elderly patients, while combined brain injuries with SDH result from a severe global traumatic brain injury combining different pathophysiologic mechanisms often in younger patients. The groups were analyzed for patient demographics, clinical presentation, and association with coagulation disorders. The significance level was set at p\u2009&lt;\u20090.005.<\/jats:p><jats:p>\n          Results\u2003The presence of an iSDH was associated with a higher likelihood of concomitant coagulation disorder or anticoagulants in cases of isolated subdural hemorrhage (56.8% of the population in SDH vs. 94.7% in SDH\u2009+\u2009iSDH, p\u2009&lt;\u20090.005). This effect was not significant in the cases with combined traumatic brain injuries (33.3% in Combi vs. 53.6% in Combi\u2009+\u2009iSDH, p\u2009&gt;\u20090.005).<\/jats:p><jats:p>\n          Conclusion\u2003Our data indicate a high positive predictive value (PPV\u2009=\u200994.7%) for coagulation disorders in traumatic SDH patients with iSDH without any further focal and diffuse brain injuries. We consider this a relevant finding since it hints at the presence of coagulation disorders and might be used in early hemostaseologic assessment and emergency management.<\/jats:p>","DOI":"10.1055\/s-0043-1777859","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T23:36:07Z","timestamp":1711755367000},"page":"148-155","source":"Crossref","is-referenced-by-count":2,"title":["The Extension of Traumatic Subdural Hematoma into the Interhemispheric Fissure Is Associated with Coagulation Disorders: A Retrospective Study"],"prefix":"10.1055","volume":"86","author":[{"given":"Lennart W.","family":"Sannwald","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Vivantes Friedrichshain Hospital, Charit\u00e9 Academic Teaching Hospital, Landsberger Allee, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dag","family":"Moskopp","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Vivantes Friedrichshain Hospital, Charit\u00e9 Academic Teaching Hospital, Landsberger Allee, Berlin, Germany"},{"name":"Department of Health, Social Affairs \u2013 Education, European Technical College EUFH, Rolandufer, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4233-3140","authenticated-orcid":false,"given":"Mats L.","family":"Moskopp","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Vivantes Friedrichshain Hospital, Charit\u00e9 Academic Teaching Hospital, Landsberger Allee, Berlin, Germany"},{"name":"Institute of Physiology, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden, Fetscherstrasse, Dresden, 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