{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T01:43:52Z","timestamp":1785894232824,"version":"3.56.0"},"reference-count":50,"publisher":"Georg Thieme Verlag KG","issue":"04","funder":[{"name":"National Council for Scientific and Technological Development\u2014CNPq","award":["402867\/2017-3"],"award-info":[{"award-number":["402867\/2017-3"]}]},{"name":"Milligramm Homeopathic Pharmacy, Florian\u00f3polis, SC, Brazil","award":["15.392.920\/0001-70"],"award-info":[{"award-number":["15.392.920\/0001-70"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The blowfly Cochliomyia hominivorax (Diptera: Calliphoridae) causes traumatic myiasis in farm animals, with deeply embedded larvae that lead to serious tissue damage and sometimes death. Treating this form of myiasis is difficult, often resulting in poor outcomes. As a homeopathic preparation that can mimic traumatic myiasis symptoms, Pyrogenium could potentially supplement treatment. This study aimed to describe the adjuvant effect that a Pyrogenium ointment might have in the treatment of sheep with traumatic myiasis.<\/jats:p><jats:p>\n          Patients\u2003The study reports a homeopathic adjuvant treatment with Pyrogenium 12cH ointment in six sheep with traumatic and infected myiasis. Daily clinical examinations were performed to monitor the evolution of the health of animals. Pyrogenium 12cH ointment was applied topically on the wounds, after cleaning and mechanical removal of the larvae from the lesion. Blood samples were collected for blood counts, and wound exudate samples were obtained for bacteriological examination before and after wound treatment.<\/jats:p><jats:p>\n          Results\u2003The ointment of Pyrogenium 12cH limited the development of parasitic larvae and was associated with the repair of tissue losses resulting from the myiases and with subsequent wound healing, together with control of fever and local inflammation.<\/jats:p><jats:p>\n          Conclusion\u2003Homeopathic Pyrogenium 12cH, formulated as an ointment, may be a useful new and adjuvant therapeutic option for treating traumatic and infected myiasis in animals.<\/jats:p>","DOI":"10.1055\/s-0043-1778066","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T23:58:41Z","timestamp":1711670321000},"page":"262-273","source":"Crossref","is-referenced-by-count":4,"title":["Homeopathic Pyrogenium Ointment as Adjuvant in Treatment of Traumatic and Infected Myiasis by Cochliomyia Hominivorax (Diptera: Calliphoridae) in Sheep: A Case Series"],"prefix":"10.1055","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1212-6749","authenticated-orcid":false,"given":"Giuliano Pereira de","family":"Barros","sequence":"additional","affiliation":[{"name":"Departamento de Zootecnia e Desenvolvimento Rural, Programa de P\u00f3s Gradua\u00e7\u00e3o em Agroecossistemas, Centro de Ci\u00eancias Agr\u00e1rias, Universidade Federal de Santa Catarina. Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise Pereira","family":"Leme","sequence":"additional","affiliation":[{"name":"Departamento de Zootecnia e Desenvolvimento Rural, Programa de P\u00f3s Gradua\u00e7\u00e3o em Agroecossistemas, Centro de Ci\u00eancias Agr\u00e1rias, Universidade Federal de Santa Catarina. Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia Ana","family":"Bricarello","sequence":"additional","affiliation":[{"name":"Departamento de Zootecnia e Desenvolvimento Rural, Programa de P\u00f3s Gradua\u00e7\u00e3o em Agroecossistemas, Centro de Ci\u00eancias Agr\u00e1rias, Universidade Federal de Santa Catarina. Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,3,28]]},"reference":[{"key":"ref1","first-page":"623","volume-title":"Myiasis","author":"A Singh","year":"2022"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1590\/s1984-29612019059","article-title":"A review on the occurrence of Cochliomyia hominivorax (Diptera: Calliphoridae) in Brazil","volume":"28","author":"L M Costa-J\u00fanior","year":"2019","journal-title":"Rev Bras Parasitol Vet"},{"key":"ref3","first-page":"1","volume-title":"Myiasis-causing flies","author":"C Brisola","year":"2020"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1146\/annurev-ento-010715-023655","article-title":"Traumatic myiasis: a neglected disease in a changing world","volume":"61","author":"M JR Hall","year":"2016","journal-title":"Annu Rev Entomol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4236\/ojvm.2020.106007","article-title":"Myiasis by Cochliomyia hominivorax (Coquerel, 1858): a neglected zoonosis in Brazil","volume":"10","author":"G P de Barros","year":"2020","journal-title":"Open J Vet Med"},{"key":"ref6","first-page":"393","volume-title":"Myiasis. 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