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Further, the symbiotic relationship between the vaginal microbiome and the cervical mucus plug is highlighted, with a special emphasis on how this natural barrier serves as a guardian against ascending infections. Understanding this complex host\u2013microbes interplay could pave the way for innovative approaches to improve women's reproductive health and fertility.<\/jats:p>","DOI":"10.1055\/s-0043-1778661","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T23:49:06Z","timestamp":1706053746000},"page":"200-208","source":"Crossref","is-referenced-by-count":3,"title":["Microenvironment of the Lower Reproductive Tract: Focus on the Cervical Mucus Plug"],"prefix":"10.1055","volume":"41","author":[{"given":"Susana","family":"Ruiz-Dur\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Virgen de las Nieves University Hospital, Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA, Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia M.","family":"Tenorio","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Faculty 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