{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:59:52Z","timestamp":1784919592901,"version":"3.55.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngo-Rhino-Otol"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die Standardtherapie der GERD mit PPI ist weniger wirksam als gedacht: Mindestens 30 % der Patienten haben\n                    persistierende Symptome und L\u00e4sionen (Therapiel\u00fccke). Bei persistierender Symptomatik oder Wunsch einer\n                    alternativen Behandlung ist eine stratifizierte Diagnostik erforderlich. Alginate und neue Operationsverfahren\n                    erweitern die Therapieoptionen<\/jats:p>","DOI":"10.1055\/s-0044-100740","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T18:34:30Z","timestamp":1519929270000},"page":"166-175","source":"Crossref","is-referenced-by-count":1,"title":["Gastro\u00f6sophageale Refluxkrankheit \u2013 was tun, wenn PPI nicht ausreichend wirksam,\n                    vertr\u00e4glich oder erw\u00fcnscht sind?"],"prefix":"10.1055","volume":"97","author":[{"given":"Joachim","family":"Labenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Koop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,3,1]]},"container-title":["Laryngo-Rhino-Otologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-100740.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T18:34:37Z","timestamp":1519929277000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-100740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,3,1]]},"published-print":{"date-parts":[[2018,3]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-100740","relation":{},"ISSN":["0935-8943","1438-8685"],"issn-type":[{"value":"0935-8943","type":"print"},{"value":"1438-8685","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}