{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T20:37:05Z","timestamp":1773088625866,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Z Gastroenterol"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Purpose\u2002The purpose of this study was to determine accuracy and necessity of long-term Doppler ultrasound (DU) surveillance of transjugular intrahepatic portosystemic shunt (TIPS) patency after implantation of an ePTFE-covered stent-graft (Viatorr).<\/jats:p><jats:p>\n          Methods\u2002This single-center retrospective study includes 228 consecutive cirrhotic patients with TIPS implantation due to portal hypertensive complications. Standardized DU surveillance was scheduled 3\u200a\u2013\u200a5 days, 3 months, and 6 months after TIPS implantation and every 6 months thereafter. Portal venography was performed in case of DU findings suspicious of TIPS dysfunction, clinical signs of recurrent portal hypertension, or refractory hepatic encephalopathy.<\/jats:p><jats:p>\n          Results\u2002During a mean follow-up of 16.6\u200a\u00b1\u200a23.4 months, 866 DU examinations were performed. Twenty-two cases of TIPS dysfunction were observed in 16 patients with no first dysfunction more than 4 years after implantation. Routine DU in asymptomatic patients had little therapeutic impact (0.75\u200a%). DU and venography were concordant in 39\/46 (84.8\u200a%) paired examinations, and 1-, 2-, and 5-year primary TIPS patency was 87.4\u200a%, 83.7\u200a%, and 79.97\u200a%, respectively. Patients with TIPS dysfunction and subsequent successful revision during the first 2 years of follow-up had a significantly higher risk (p\u200a=\u200a0.001) of new dysfunction compared to those without TIPS dysfunction. Cumulative 1-, 2-, and 5-year survival was 68.7\u200a%, 61.3\u200a%, and 42.7\u200a%, respectively.<\/jats:p><jats:p>\n          Conclusions\u2002Despite acceptable accuracy, scheduled DU surveillance proved to have minor therapeutic impact. Thus, detailed DU surveillance is not useful in asymptomatic patients after 2 years of unremarkable follow-up.\u200aIn contrast, long-term DU surveilleance should be performed in patients after successful revision of TIPS dysfunction and patients with prothrombotic states (e.\u200ag., portal vein thrombosis, Budd-Chiari syndrome).<\/jats:p>","DOI":"10.1055\/s-0044-102107","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T18:40:53Z","timestamp":1537209653000},"page":"1053-1062","source":"Crossref","is-referenced-by-count":9,"title":["Doppler ultrasound surveillance of TIPS-patency in the era of covered stents \u2013 retrospective analysis of a large single-center cohort"],"prefix":"10.1055","volume":"56","author":[{"given":"Christoph","family":"Klinger","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Klinikum Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bettina","family":"Riecken","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Klinikum Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Klinikum Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anja","family":"Westphal","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Klinikum Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"L\u00f6ffler","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Klinikum Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eckhart","family":"Froehlich","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Universi\u00e4t T\u00fcbingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karel","family":"Caca","sequence":"additional","affiliation":[{"name":"Medizinische Klinik I, Klinikum Ludwigsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,9,17]]},"container-title":["Zeitschrift f\u00fcr Gastroenterologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-102107.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T18:41:01Z","timestamp":1537209661000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-102107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":0,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2018,9,17]]},"published-print":{"date-parts":[[2018,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-102107","relation":{},"ISSN":["0044-2771","1439-7803"],"issn-type":[{"value":"0044-2771","type":"print"},{"value":"1439-7803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}