{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T14:06:41Z","timestamp":1770905201786,"version":"3.50.1"},"reference-count":23,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Angiol"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Heart failure (HF) is one of the most common diagnoses on admission to hospital in Germany, and one which incurs high costs. Integrated care in case management programs (CMPs) aims to improve treatment quality in the sense of guideline-driven treatment, while reducing hospital admissions, hospital costs, and mortality. A total of 1,844 patient data records from 11 German statutory health insurance companies enrolled in the CMP (intervention group [IG]) were compared with 1,844 standard-care patients (control group) using propensity score matching. The two groups were assessed over three follow-up observation periods regarding the endpoints' treatment costs, hospitalization rate, indicators for treatment quality (diagnostics, physician contact), and mortality. The evaluation revealed no significant differences regarding overall costs. The IG incurred significantly higher outpatient costs, but the medication costs and inpatient costs were not significantly different. There were also no significant differences in the number of hospital admissions. Patients within the CMP had significantly more frequent contact with a cardiologist, and underwent echocardiographic examination significantly more frequently. Mortality during the first follow-up observation year was considerably more favorable for the IG. There are indications that treatment quality is improved in HF patients.<\/jats:p>","DOI":"10.1055\/s-0044-1779660","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T23:51:07Z","timestamp":1707522667000},"page":"165-173","source":"Crossref","is-referenced-by-count":1,"title":["Are Hospital Admissions (Costs) and Mortality Rate Impacted by Guideline-driven Treatment of Heart Failure?: A Comparison between Participants in the \u201cCorBene\u201d CMP and Standard-care Patients on the Basis of Propensity Score Matching"],"prefix":"10.1055","volume":"33","author":[{"given":"Josef","family":"Ehling","sequence":"additional","affiliation":[{"name":"Department of Imaging Diagnostics, German Air Force Centre for Aerospace Medicine, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans J\u00fcrgen","family":"Nobl\u00e9","sequence":"additional","affiliation":[{"name":"Department of Imaging Diagnostics, German Air Force Centre for Aerospace Medicine, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Detlef","family":"Gysan","sequence":"additional","affiliation":[{"name":"Medizinisches Versorgungszentrum GbR, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mareike","family":"M\u00f6ller","sequence":"additional","affiliation":[{"name":"Medizinisches Versorgungszentrum GbR, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"Goss","sequence":"additional","affiliation":[{"name":"Department of Imaging Diagnostics, German Air Force Centre for Aerospace Medicine, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winfried","family":"Haerer","sequence":"additional","affiliation":[{"name":"Department of Imaging Diagnostics, German Air Force Centre for Aerospace Medicine, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Gl\u00fcck","sequence":"additional","affiliation":[{"name":"Department of Imaging Diagnostics, German Air Force Centre for Aerospace Medicine, K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2234-4851","authenticated-orcid":false,"given":"Paul Martin","family":"Bansmann","sequence":"additional","affiliation":[{"name":"K\u00f6ln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,9]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1161\/CIRCRESAHA.113.300268","article-title":"Epidemiology of heart failure","volume":"113","author":"V L Roger","year":"2013","journal-title":"Circ Res"},{"issue":"11","key":"ref2","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1007\/s00392-017-1137-7","article-title":"Epidemiology of heart failure in Germany: a retrospective database study","volume":"106","author":"S St\u00f6rk","year":"2017","journal-title":"Clin Res Cardiol"},{"issue":"10","key":"ref3","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1007\/s00392-019-01444-8","article-title":"Higher prevalence of heart failure in rural regions: a population-based study covering 87% of German inhabitants","volume":"108","author":"J Holstiege","year":"2019","journal-title":"Clin Res Cardiol"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/ehf2.12021","article-title":"Improving care for patients with acute heart failure: before, during and after hospitalization","volume":"1","author":"M R Cowie","year":"2014","journal-title":"ESC Heart Fail"},{"issue":"08","key":"ref5","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1002\/ejhf.567","article-title":"Heart failure epidemiology 2000-2013: insights from the German Federal Health Monitoring System","volume":"18","author":"M Christ","year":"2016","journal-title":"Eur J Heart Fail"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/978-3-662-62708-2","volume-title":"Krankenhaus-Report 2021: Versorgungsketten\u2013Der Patient im Mittelpunkt","author":"J Klauber","year":"2021"},{"issue":"20","key":"ref7","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1001\/jama.2012.14785","article-title":"Association between use of renin-angiotensin system antagonists and mortality in patients with heart failure and preserved ejection fraction","volume":"308","author":"L H Lund","year":"2012","journal-title":"JAMA"},{"issue":"06","key":"ref8","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/ejhf.566","article-title":"European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions","volume":"18","author":"M G Crespo-Leiro","year":"2016","journal-title":"Eur J Heart Fail"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"e411","DOI":"10.1016\/S2214-109X(20)30004-8","article-title":"Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): a cohort study","volume":"8","author":"J Tromp","year":"2020","journal-title":"Lancet Glob Health"},{"key":"ref10","volume-title":"Sektoren\u00fcbergreifende Versorgungsanalyse zur Kardiologie, Herzchirurgie und Kinderherzmedizin in Deutschland","author":"Deutscher Herzbericht","year":"2020"},{"issue":"10","key":"ref12","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/eurjhf\/hft134","article-title":"Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines? Evidence from 12,440 patients of the ESC Heart Failure Long-Term Registry","volume":"15","author":"A P Maggioni","year":"2013","journal-title":"Eur J Heart Fail"},{"issue":"24","key":"ref14","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/eurheartj\/ehx026","article-title":"Determinants and clinical outcome of uptitration of ACE-inhibitors and beta-blockers in patients with heart failure: a prospective European study","volume":"38","author":"W Ouwerkerk","year":"2017","journal-title":"Eur Heart J"},{"issue":"10","key":"ref15","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/j.cjca.2017.05.011","article-title":"Multidisciplinary heart failure clinics are associated with lower heart failure hospitalization and mortality: systematic review and meta-analysis","volume":"33","author":"S Gandhi","year":"2017","journal-title":"Can J Cardiol"},{"issue":"27","key":"ref16","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"P Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"issue":"15","key":"ref18","first-page":"264","article-title":"Case-Management-Programm f\u00fcr Patienten mit chronischer Herzinsuffizienz: Effektivit\u00e4t in Bezug auf die Mortalit\u00e4t, Krankenhauseinweisungen und-kosten","volume":"111","author":"V Hendricks","year":"2014","journal-title":"Dtsch Arztebl"},{"issue":"01","key":"ref19","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/biomet\/70.1.41","article-title":"The central role of the propensity score in observational studies for causal effects","volume":"70","author":"P R Rosenbaum","year":"1983","journal-title":"Biometrika"},{"issue":"10","key":"ref20","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.cardfail.2018.04.008","article-title":"Cost-effectiveness benefits of a disease management program: the REMADHE Trial Results","volume":"24","author":"E A Bocchi","year":"2018","journal-title":"J Card Fail"},{"issue":"01","key":"ref21","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/1474515114556031","article-title":"Systematic review of trial-based analyses reporting the economic impact of heart failure management programs compared with usual care","volume":"15","author":"S Maru","year":"2016","journal-title":"Eur J Cardiovasc Nurs"},{"issue":"01","key":"ref22","first-page":"CD002752","article-title":"Disease management interventions for heart failure","volume":"1","author":"A Takeda","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"01","key":"ref23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1161\/CIRCHEARTFAILURE.109.885210","article-title":"Recent national trends in readmission rates after heart failure hospitalization","volume":"3","author":"J S Ross","year":"2010","journal-title":"Circ Heart Fail"},{"key":"ref24","volume-title":"Krankenhaus-Report 2016: Schwerpunkt: Ambulant im Krankenhaus","author":"J Klauber","year":"2016"},{"issue":"06","key":"ref25","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.zefq.2013.08.010","article-title":"Leitliniengerechte Behandlung bei chronischer Herzinsuffizienz im Rahmen der Hausarztzentrierten Versorgung. Ergebnisse einer Evaluationsstudie","volume":"107","author":"I Roehl","year":"2013","journal-title":"Z Evid Fortbild Qual Gesundhwes"},{"issue":"03","key":"ref26","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1055\/a-1429-2610","article-title":"Herzinsuffizienzbehandlung in Integrierten Versorgungsmodellen nach \u00a7 140 SGB V","volume":"10","author":"D Gysan","year":"2021","journal-title":"Aktuelle Kardiologie"}],"container-title":["International Journal of Angiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1779660.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T12:06:51Z","timestamp":1730808411000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1779660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,9]]},"references-count":23,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2024,8,9]]},"published-print":{"date-parts":[[2024,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1779660","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1061-1711","1615-5939"],"issn-type":[{"value":"1061-1711","type":"print"},{"value":"1615-5939","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,9]]}}}