{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T19:28:14Z","timestamp":1771270094538,"version":"3.50.1"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003In this research, the authors provide a retrospective cohort study of 82 patients with suprasellar meningiomas to identify predictors of the visual outcome following surgery. We also conducted a matched retrospective case\u2013control analysis.<\/jats:p><jats:p>\n          Methods\u2003This retrospective cohort study included all patients who underwent craniotomy for surgical excision of suprasellar meningiomas at our institution between January 2016 and March 2022. We designed a matched case\u2013control study for patients with and without early intradural optic canal decompression (IOCD). We also developed a machine learning model to have the best possible sensitivity for the prediction of visual recovery after surgery.<\/jats:p><jats:p>\n          Results\u2003The visual acuity score (VAS) improved in 46.3% of our cases and decreased in 7.4% of the 82 included cases postoperatively. The VAS did not change in 46.3% of the patients after surgery. Statistically, visual complaints, optic atrophy, tuberculum sella involvement, and olfactory groove involvement were associated with lower preoperative VAS and visual field index (VFI). Only intracavernous sinus (ICS) extension and intraoperative vascular involvement were significantly associated with lower postoperative mean VAS correction. The outcome analysis revealed that the improvement in VAS and VFI after surgery was not statistically different between the groups with and without early IOCD (p-value\u2009=\u20091).<\/jats:p><jats:p>\n          Conclusion\u2003ICS extension was the only location-related factor associated with increased tumor recurrence or regrowth, which makes postoperative radiotherapy more valuable in patients with cavernous sinus extension. Our study results did not support the efficacy of early IOCD in increasing postoperative VAS and VFI.<\/jats:p>","DOI":"10.1055\/s-0044-1779671","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T23:56:29Z","timestamp":1708732589000},"page":"058-065","source":"Crossref","is-referenced-by-count":1,"title":["Visual Outcomes after Suprasellar Meningioma Resection: A Retrospective Cohort Study and a Machine Learning-Based Predictive Model"],"prefix":"10.1055","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5932-9375","authenticated-orcid":false,"given":"Arad","family":"Iranmehr","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex (IKHC), Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammadreza","family":"Chavoshi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Zeinalizadeh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex (IKHC), Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,2,23]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00165654","article-title":"Surgical treatment of anterior basal meningiomas","volume":"29","author":"F DeMonte","year":"1996","journal-title":"J Neurooncol"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1055\/s-0042-1745817","article-title":"Tuberculum sella meningioma: surgical management and results with emphasis on visual outcome","volume":"13","author":"R Kachhara","year":"2022","journal-title":"J Neurosci Rural Pract"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1097\/00006123-200212000-00013","article-title":"Tuberculum sellae meningiomas: microsurgical anatomy and surgical technique","volume":"51","author":"G I Jallo","year":"2002","journal-title":"Neurosurgery"},{"issue":"05","key":"ref4","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.3171\/2020.2.JNS193009","article-title":"Predictors of visual functional outcome following treatment for cavernous sinus meningioma","volume":"134","author":"N Fatima","year":"2020","journal-title":"J Neurosurg"},{"issue":"07","key":"ref5","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1136\/jnnp.2004.039974","article-title":"Surgical management of tuberculum sellae meningiomas: involvement of the optic canal and visual outcome","volume":"76","author":"U Schick","year":"2005","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1007\/s10143-021-01716-w","article-title":"Predictors of visual function after resection of skull base meningiomas with extradural anterior clinoidectomy","volume":"45","author":"G Baucher","year":"2022","journal-title":"Neurosurg Rev"},{"issue":"07","key":"ref7","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1007\/s00701-013-1741-x","article-title":"Impact of anterior clinoidectomy on visual function after resection of meningiomas in and around the optic canal","volume":"155","author":"J Lehmberg","year":"2013","journal-title":"Acta Neurochir (Wien)"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s11060-019-03128-9","article-title":"Trans-eyebrow supraorbital keyhole approach to tuberculum sellae meningiomas: a series of 30 cases with long-term visual outcomes and recurrence rates","volume":"142","author":"M Cai","year":"2019","journal-title":"J Neurooncol"},{"issue":"10","key":"ref9","doi-asserted-by":"crossref","first-page":"e297","DOI":"10.1371\/journal.pmed.0040297","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration","volume":"4","author":"J P Vandenbroucke","year":"2007","journal-title":"PLoS Med"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1200\/JCO.1984.2.3.187","article-title":"Karnofsky performance status revisited: reliability, validity, and guidelines","volume":"2","author":"C C Schag","year":"1984","journal-title":"J Clin Oncol"},{"key":"ref11","first-page":"12","article-title":"Scikit-learn: machine learning in Python","volume":"\u2022\u2022\u2022","author":"F Pedregosa","year":"2012","journal-title":"J Mach Learn Res"},{"key":"ref12","first-page":"ons108","article-title":"Optic canal involvement in tuberculum sellae meningiomas: influence on approach, recurrence, and visual recovery","volume":"67","author":"M Mahmoud","year":"2010","journal-title":"Neurosurgery"},{"issue":"04","key":"ref13","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.otc.2011.06.012","article-title":"Tuberculum sella meningioma","volume":"44","author":"C Hayhurst","year":"2011","journal-title":"Otolaryngol Clin North Am"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.surneu.2005.11.059","article-title":"Tuberculum sellae meningiomas: functional outcome in a consecutive series treated microsurgically","volume":"66","author":"H Bassiouni","year":"2006","journal-title":"Surg Neurol"},{"issue":"06","key":"ref15","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.clineuro.2011.12.021","article-title":"Visual outcome after fronto-temporo-orbito-zygomatic approach combined with early extradural and intradural optic nerve decompression in tuberculum and diaphragma sellae meningiomas","volume":"114","author":"P Mortini","year":"2012","journal-title":"Clin Neurol Neurosurg"},{"issue":"04","key":"ref16","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1227\/01.neu.0000318169.75095.cb","article-title":"Effect of early optic canal unroofing on the outcome of visual functions in surgery for meningiomas of the tuberculum sellae and planum sphenoidale","volume":"62","author":"K Nozaki","year":"2008","journal-title":"Neurosurgery"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.wneu.2018.02.032","article-title":"Optic nerve atrophy due to long-standing compression by planum sphenoidale meningioma","volume":"113","author":"A Di Somma","year":"2018","journal-title":"World Neurosurg"},{"issue":"01","key":"ref18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00041327-200303000-00001","article-title":"Management of suprasellar meningiomas","volume":"23","author":"W F Chandler","year":"2003","journal-title":"J Neuroophthalmol"},{"issue":"11","key":"ref19","doi-asserted-by":"crossref","first-page":"3243","DOI":"10.3390\/cancers12113243","article-title":"Midline meningiomas of the anterior skull base: surgical outcomes and a decision-making algorithm for classic skull base approaches","volume":"12","author":"A K Aftahy","year":"2020","journal-title":"Cancers (Basel)"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.21608\/mjcu.2018.65673","article-title":"Lateral supraorbital approach versus classic pterional approach in suprasellar meningiomas regarding accessibility and safety","volume":"86","author":"A A Abd El-Khalek","year":"2018","journal-title":"Med J Cairo Univ"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"560706","DOI":"10.3389\/fonc.2020.560706","article-title":"Resection of olfactory groove meningiomas through unilateral vs. bilateral approaches: a systematic review and meta-analysis","volume":"10","author":"A Y Feng","year":"2020","journal-title":"Front Oncol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.clineuro.2018.08.029","article-title":"Olfactory groove and tuberculum sellae meningioma resection by endoscopic endonasal approach versus transcranial approach: a systematic review and meta-analysis of comparative studies","volume":"174","author":"V M Lu","year":"2018","journal-title":"Clin Neurol Neurosurg"},{"issue":"04","key":"ref23","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1055\/s-0033-1342920","article-title":"Tuberculum sellae meningiomas: surgical technique, visual outcome, and prognostic factors in 51 cases","volume":"74","author":"N Margalit","year":"2013","journal-title":"J Neurol Surg B Skull Base"},{"issue":"02","key":"ref24","doi-asserted-by":"crossref","first-page":"380","DOI":"10.3171\/2018.10.JNS181480","article-title":"Outcomes of decompressive surgery for cavernous sinus meningiomas: long-term follow-up in 50 patients","volume":"132","author":"Y M Gozal","year":"2020","journal-title":"J Neurosurg"},{"issue":"04","key":"ref25","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1055\/s-0040-1715471","article-title":"Cavernous sinus meningioma with orbital involvement: algorithmic decision-making and treatment strategy","volume":"81","author":"A Raheja","year":"2020","journal-title":"J Neurol Surg B Skull Base"},{"issue":"12","key":"ref26","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1007\/s00701-018-3711-9","article-title":"Radiosurgery and fractionated radiotherapy for cavernous sinus meningioma: a systematic review and meta-analysis","volume":"160","author":"H A Leroy","year":"2018","journal-title":"Acta Neurochir (Wien)"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"e509","DOI":"10.1016\/j.wneu.2021.11.015","article-title":"Supraorbital keyhole craniotomy via eyebrow incision: a systematic review and meta-analysis","volume":"158","author":"Z M Robinow","year":"2022","journal-title":"World Neurosurg"},{"issue":"03","key":"ref28","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s00701-019-04114-w","article-title":"Surgical management of tuberculum sellae meningiomas: myths, facts, and controversies","volume":"162","author":"L Giammattei","year":"2020","journal-title":"Acta Neurochir (Wien)"}],"container-title":["Journal of Neurological Surgery Part B: Skull Base"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1779671.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T00:20:49Z","timestamp":1738110049000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1779671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,23]]},"references-count":28,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2025,1,28]]},"published-print":{"date-parts":[[2025,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1779671","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2193-6331","2193-634X"],"issn-type":[{"value":"2193-6331","type":"print"},{"value":"2193-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,23]]}}}