{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T17:50:39Z","timestamp":1774893039223,"version":"3.50.1"},"reference-count":7,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Resource-limited burn centers are usually devoid of cultured epithelial autografts (CEA) owing largely to prohibitive costs. A modified CEA technique at our burn center incorporated cost-effective, routinely-used dressings with favorable outcomes. One unknown concern was the immunosuppressive effect that extensive burns and potentially human immunodeficiency virus (HIV) infection may have on graft take. This case study reports on the graft take outcomes of the first CEA transplanted in an HIV-positive patient with extensive burns in South Africa, using this technique. Graft take was determined after 21 days at 80% and a long-term follow-up of 8 years indicated good pigmentation return and skin pliability. Delayed diagnosis of pyoderma gangrenosum caused partial graft loss; however, successful regrafting occurred after pyoderma gangrenosum treatment and eradication. The case was considered clinically successful. HIV may not directly affect graft take, but may result in immunosuppressive conditions that delay graft take success.<\/jats:p>","DOI":"10.1055\/s-0044-1782540","type":"journal-article","created":{"date-parts":[[2024,3,23]],"date-time":"2024-03-23T00:32:17Z","timestamp":1711153937000},"page":"401-403","source":"Crossref","is-referenced-by-count":2,"title":["A Case Report of the First CEA Transplant in an HIV-Positive Burn Patient in South Africa Using a Novel Composite Culture Technique"],"prefix":"10.1055","volume":"57","author":[{"given":"Wayne George","family":"Kleintjes","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University Medical School, Parow, Cape Town, Western Cape, South Africa"},{"name":"Western Cape Provincial Adult Tertiary Burns Centre, Tygerberg Hospital, Tygerberg, Parow, Cape Town, Western Cape, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarryn Kay","family":"Prinsloo","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, Cape Town, Western Cape, South Africa"},{"name":"Department of Emergency Medical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, Cape Town, Western Cape, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1093\/cid\/cix682","article-title":"Bacterial infections after burn injuries: impact of multidrug resistance","volume":"65","author":"A M Lachiewicz","year":"2017","journal-title":"Clin Infect Dis"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/01.sla.0000250422.36168.67","article-title":"The effects of preexisting medical comorbidities on mortality and length of hospital stay in acute burn injury: evidence from a national sample of 31,338 adult patients","volume":"245","author":"B D Thombs","year":"2007","journal-title":"Ann Surg"},{"issue":"07","key":"ref3","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.burns.2004.03.014","article-title":"Immune response in burn patients in relation to HIV infection and sepsis","volume":"30","author":"T Sj\u00f6berg","year":"2004","journal-title":"Burns"},{"key":"ref4","first-page":"1579","article-title":"A novel technique for composite cultured epithelial autograft in a patient with extensive burn wounds: a case report","volume":"2","author":"W Kleintjes","year":"2017","journal-title":"Clin Surg"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/00004630-199005000-00014","article-title":"Rating the burn scar","volume":"11","author":"T Sullivan","year":"1990","journal-title":"J Burn Care Rehabil"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/00004630-199001000-00015","article-title":"Delayed autograft loss in HIV-positive patients: two cases","volume":"11","author":"A R DeLaney","year":"1990","journal-title":"J Burn Care Rehabil"},{"issue":"01","key":"ref7","first-page":"17","article-title":"Challenges in diagnosing pyoderma gangrenosum in a severely burned patient: case report and literature review","volume":"4","author":"W Kleintjes","year":"2021","journal-title":"South African J Plast Reconstr Aesthetic Surg Burn"}],"container-title":["Indian Journal of Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1782540.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T00:42:05Z","timestamp":1731717725000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1782540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,22]]},"references-count":7,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2024,11,15]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1782540","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0970-0358","1998-376X"],"issn-type":[{"value":"0970-0358","type":"print"},{"value":"1998-376X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,22]]}}}