{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T19:45:57Z","timestamp":1782330357088,"version":"3.54.5"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T00:00:00Z","timestamp":1716595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Mismatch negativity (MMN) represents a negative component of event-related potentials, which is mentioned by guidelines as an important tool to provide measurable data regarding the functionality of the auditory system in acoustic processing. However, the literature still lacks reliable data that can support the clinical use of this potential in the complementary diagnosis of central auditory processing (CAP) disorder (CAPD).<\/jats:p><jats:p>\n          Objectives\u2003To analyze whether MMN assessment might be associated with the CAP behavioral test battery, as well as to assess the effects of auditory ability deficits on MMN responses in the pediatric population.<\/jats:p><jats:p>\n          Methods\u2003In total, 45 age-matched children participated in the study. They were submitted to the CAP behavior assessment and to MMN. The children were tested with a combination of speech contrast consisting of acoustic syllables [da] versus [ta], governed by the oddball paradigm.<\/jats:p><jats:p>\n          Results\u2003Mismatch negativity did not show a direct association with a single test but with the combination of the four tests used as a behavioral test battery to identify CAPD. The results also indicated that the auditory ability deficits influenced the measurement of MMN latency (p\u2009=\u20090.003*), but not the amplitude (p\u2009=\u20090.857) or the area (p\u2009=\u20090.577).<\/jats:p><jats:p>\n          Conclusion\u2003Mismatch negativity was shown to be statistically associated with the battery of tests used to identify deficits in auditory abilities in the studied sample rather than with a single behavioral test. The deficits in auditory abilities were observed in the MMN latency. Mismatch negativity can be used to assess children with CAPD.<\/jats:p>","DOI":"10.1055\/s-0044-1785458","type":"journal-article","created":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T22:30:20Z","timestamp":1716676220000},"page":"e561-e567","source":"Crossref","is-referenced-by-count":3,"title":["Mismatch Negativity in Children with Deficits in Auditory Abilities"],"prefix":"10.1055","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9799-3229","authenticated-orcid":false,"given":"Julia Dalcin","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Speech Therapy, Centro de Ci\u00eancias da Sa\u00fade, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9borah Aur\u00e9lio","family":"Temp","sequence":"additional","affiliation":[{"name":"Department of Speech Therapy, Centro de Ci\u00eancias da Sa\u00fade, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3244-025X","authenticated-orcid":false,"given":"La\u00eds","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Speech Therapy, Centro de Ci\u00eancias da Sa\u00fade, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e1lia El Hatal de","family":"Souza","sequence":"additional","affiliation":[{"name":"Department of Speech Therapy, Centro de Ci\u00eancias da Sa\u00fade, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Vargas","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Speech Therapy, Centro de Ci\u00eancias da Sa\u00fade, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, 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eletrofisiol\u00f3gica","year":"2016"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1055\/s-0035-1564458","article-title":"Auditory Training for Central Auditory Processing Disorder","volume":"36","author":"J Weihing","year":"2015","journal-title":"Semin Hear"},{"issue":"07","key":"ref5","doi-asserted-by":"crossref","first-page":"676","DOI":"10.3766\/jaaa.25.7.6","article-title":"Attend to this: the relationship between auditory processing disorders and attention deficits","volume":"25","author":"P Gyldenk\u00e6rne","year":"2014","journal-title":"J Am Acad Audiol"},{"issue":"02","key":"ref6","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1044\/2015_AJA-14-0037","article-title":"It Is Time to Rethink Central Auditory Processing Disorder Protocols for School-Aged Children","volume":"24","author":"D A DeBonis","year":"2015","journal-title":"Am J 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language impairment and auditory processing disorder","volume":"81","author":"C N Rocha-Muniz","year":"2015","journal-title":"Rev Bras Otorrinolaringol (Engl Ed)"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.neuroscience.2017.01.011","article-title":"Abnormalities in cortical auditory responses in children with central auditory processing disorder","volume":"346","author":"A Koravand","year":"2017","journal-title":"Neuroscience"},{"issue":"21","key":"ref13","first-page":"e1712","article-title":"Auditory brainstem response in adults at rest and in movement","author":"A BO Lot","year":"2016","journal-title":"Audiol Commun Res"},{"issue":"03","key":"ref14","first-page":"209","article-title":"Scale of Auditory Behaviors and auditory behavior tests for auditory processing assessment in Portuguese children","volume":"25","author":"C L Nunes","year":"2013","journal-title":"CoDAS"},{"key":"ref15","volume-title":"Testes auditivos comportamentais para avalia\u00e7\u00e3o do Processamento Auditivo Central","author":"L D Pereira","year":"2011"},{"key":"ref16","volume-title":"Random Gap Detection Test","author":"R W Keith","year":"2000"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3766\/jaaa.14.1.2","article-title":"Development of a 500-Hz masking-level difference protocol for clinic use","volume":"14","author":"R H Wilson","year":"2003","journal-title":"J Am Acad Audiol"},{"issue":"03","key":"ref18","doi-asserted-by":"publisher","first-page":"e399","DOI":"10.1055\/s-0040-1713590","article-title":"Verbal and nonverbal Mismatch Negativity in children with typical development: variables analysis","volume":"25","author":"A EH de Souza","year":"2021","journal-title":"Int Arch Otorhinolaryngol"},{"issue":"04","key":"ref19","first-page":"305","article-title":"Comparison of Pre-Attentive Auditory Discrimination at Gross and Fine Difference between Auditory Stimuli","volume":"20","author":"H K 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