{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:07:34Z","timestamp":1789430854584,"version":"build-2803163510"},"reference-count":48,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Low-\/negative-pressure hydrocephalus (LPH\/NePH) is uncommon in clinical practice, and doctors are unfamiliar with it. LPH\/NePH is frequently caused by other central nervous system diseases, and patients are frequently misdiagnosed with other types of hydrocephalus, resulting in delayed treatment. LPH\/NePH therapy evolved to therapeutic measures based on \u201cexternal ventricular drainage below atmospheric pressure\u201d as the number of patients with LPH\/NePH described in the literature has increased. However, the mechanism of LPH\/NePH formation is unknown. Thus, understanding the process of LPH\/NePH development is the most important step in improving diagnosis and treatment capability. Based on case reports of LPH\/NePH, we reviewed theories of transcortical pressure difference, excessive cerebral venous drainage, brain viscoelastic changes, and porous elastic sponges.<\/jats:p>","DOI":"10.1055\/s-0044-1785671","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T22:49:00Z","timestamp":1714517340000},"page":"492-500","source":"Crossref","is-referenced-by-count":3,"title":["Low-\/Negative-Pressure Hydrocephalus: To Understand the Formation Mechanism from the Perspective of Clinicians"],"prefix":"10.1055","volume":"85","author":[{"given":"Guangzhao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The First People's Hospital of Hefei, Hefei, Anhui, Peoples' Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The First People's Hospital of Hefei, Hefei, Anhui, Peoples' 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