{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T03:39:44Z","timestamp":1793417984400,"version":"4.5.0"},"reference-count":25,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Mesenteric ischemia (Me-Is) after cardiac surgery is underreported in present literature but has still earned the bad reputation of a dismal prognosis. This study adds clinical outcomes in a large patient cohort.<\/jats:p><jats:p>\n          Methods\u2003Between 2009 and 2019 of the 22,590 patients undergoing cardiac surgery at our facility 106 (0.47%) developed Me-Is postoperatively. Retrospective patient data was analyzed. Additionally, patients were stratified by outcome\u2014survivors and nonsurvivors.<\/jats:p><jats:p>\n          Results\u2003Patients were predominantly male (n\u2009=\u200968, 64.2%), mean age was 71.2\u2009\u00b1\u20099.3 years. Most procedures were elective (n\u2009=\u200985, 80.2%) and comprised of more complex combined procedures (50.9%) and redos (17.9%). Mean EuroSCORE II averaged 10.9\u2009\u00b1\u200912.2%. Survival at 30 days was 49.1% (n\u2009=\u200952). Clinical baseline and procedural characteristics did not differ significantly between survivors and nonsurvivors. The median postoperative interval until symptom onset was 5 days in both groups. Survivors were more frequently diagnosed by computed tomography and nonsurvivors based on clinical symptoms. Me-Is was predominantly nonocclusive (n\u2009=\u200984, 79.2%). Laparotomy was the main treatment in both groups (n\u2009=\u200945, 78.8% vs. n\u2009=\u200948, 88.9%, p\u2009=\u20090.94). Predictors of mortality were maximum norepinephrine doses (hazard ratio [HR] 8.29, confidence interval [CI] 3.39\u201320.26, p\u2009&lt;\u20090.0001), lactate levels (HR 1.06, CI 1.03\u20131.09), and usage of inotropes (HR 2.46, CI 1.41\u20134.30).<\/jats:p><jats:p>\n          Conclusion\u2003The prognosis of Me-Is following cardiac surgery is poor\u2014independently from diagnostic or treatment patterns. There exists a significant asymptomatic time period postoperatively, in which pathophysiologic processes seem to cross the Rubicon. After clinical demarcation, the further course can almost no longer be influenced.<\/jats:p>","DOI":"10.1055\/s-0044-1786183","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T22:53:35Z","timestamp":1714776815000},"page":"498-509","source":"Crossref","is-referenced-by-count":6,"title":["Mesenteric Ischemia after Cardiac Surgery"],"prefix":"10.1055","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6827-2489","authenticated-orcid":false,"given":"Asen","family":"Petrov","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Heart Center Dresden, Medical Faculty Carl Gustav Carus of the Technical University of Dresden, Technische Universit\u00e4t Dresden, Dresden, Sachsen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Taghizadeh-Waghefi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Heart Center Dresden, Medical Faculty Carl Gustav Carus of the Technical University of Dresden, Technische Universit\u00e4t Dresden, Dresden, Sachsen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Hotz","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Heart Center Dresden, Medical Faculty Carl Gustav Carus of the Technical University of Dresden, Technische Universit\u00e4t Dresden, Dresden, Sachsen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Georgi","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Heart Center Dresden, Medical Faculty Carl Gustav Carus of the Technical University of Dresden, Technische Universit\u00e4t Dresden, Dresden, Sachsen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus Ehrhard","family":"Matschke","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, University Heart 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