{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T15:52:58Z","timestamp":1780847578088,"version":"3.54.1"},"reference-count":45,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:00:00Z","timestamp":1716508800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objectives\u2003The aim of this study was to evaluate and compare the effect of irradiance light and storage media on the elution of triethylene glycol dimethacrylate (TEGDMA) from conventional Filtek Z350XT 3M ESPE and two bulk-fill composites Shofu Beautifil-Bulk and Filtek Bulk fill flowable 3M ESPE using high-performance liquid chromatography (HPLC).<\/jats:p><jats:p>\n          Materials and Methods\u2003Shofu Beautifil-Bulk, Filtek Bulk fill flowable 3M ESPE, and Filtek Z350XT 3M ESPE were the three types of composites used in this study. Disk shaped samples of 4-mm thickness and 10-mm diameter were fabricated using a stainless steel mold and were polymerized using light emitting diode (LED) and quartz tungsten halogen (QTH) lamps. After polymerization, the samples were immersed in ethanol, artificial saliva with betel quid extract, and distilled water for 1, 7, and 30 days, respectively. The elution of monomer TEGDMA was evaluated using HPLC.<\/jats:p><jats:p>\n          Statistical Analysis\u2003To evaluate the mean concentration difference, mixed way analysis of variance (ANOVA) was applied. Between different light, materials, and within the time duration, Tukey's post hoc test was used. A p value of 0.05 was considered significant.<\/jats:p><jats:p>\n          Results\u2003During the first day of storage, a significant amount of monomer TEGDMA elution was seen in all the materials. The highest values observed to be in the disks cured with QTH lamp. However, the highest elution was seen when the disks were immersed in ethanol\/water solution. While the most stable medium was distilled water, artificial saliva with betel nut extract also had a significant effect on the elution of TEGDMA. The highest value obtained was of Filtek Bulk fill flowable 3M ESPE after 30 days of immersion in both LED and QTH cured disks.<\/jats:p><jats:p>\n          Conclusion\u2003Filtek Bulk fill flowable 3M ESPE shows better properties in relation to the release of monomer TEGDMA as it releases less amount of monomer in the storage media. The release of monomer was highest in ethanol as compared to artificial saliva and distilled water with the passage of time.<\/jats:p>","DOI":"10.1055\/s-0044-1786876","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T23:07:35Z","timestamp":1716592055000},"page":"061-069","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the Impact of Irradiance Lamps and Storage Media on Elution of TEGDMA from Dental Composites"],"prefix":"10.1055","volume":"19","author":[{"given":"Kiran","family":"Tauseef","sequence":"additional","affiliation":[{"name":"Department of Dental Material, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faiza","family":"Amin","sequence":"additional","affiliation":[{"name":"Department of Dental Material, Dow Dental College, Dow University of Health Sciences, Karachi, 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Mater"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"482","DOI":"10.4103\/0972-0707.190020","article-title":"Leaching of monomers from bulk-fill composites: an in vitro study","volume":"19","author":"A R Sajnani","year":"2016","journal-title":"J Conserv Dent"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1177\/10454411960070020501","article-title":"Bioavailability of components of resin-based materials which are applied to teeth","volume":"7","author":"W R Hume","year":"1996","journal-title":"Crit Rev Oral Biol Med"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s10856-005-0627-8","article-title":"Salivary bisphenol-A levels detected by ELISA after restoration with composite resin","volume":"16","author":"N Sasaki","year":"2005","journal-title":"J Mater Sci Mater 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resin-based composites restoration: a literature review","volume":"12","author":"M Tanumihardja","year":"2019","journal-title":"Journal of International Dental and Medical Research."},{"issue":"06","key":"ref10","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0109-5641(01)00069-0","article-title":"Energy dependent polymerization of resin-based composite","volume":"18","author":"R H Halvorson","year":"2002","journal-title":"Dent Mater"},{"issue":"02","key":"ref11","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/jbm.b.30179","article-title":"Influence of the power density on the kinetics of photopolymerization and properties of dental composites","volume":"72","author":"A D Neves","year":"2005","journal-title":"J Biomed Mater Res B Appl Biomater"},{"issue":"03","key":"ref12","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.dental.2019.01.005","article-title":"Long-term elution of monomers from resin-based dental 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Ferracane","year":"1992","journal-title":"J Dent Res"},{"issue":"12","key":"ref23","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1046\/j.1365-2842.2001.00802.x","article-title":"Water sorption and solubility of dental composites and identification of monomers released in an aqueous environment","volume":"28","author":"U \u00d6rtengren","year":"2001","journal-title":"J Oral Rehabil"},{"issue":"05","key":"ref24","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.dental.2014.02.023","article-title":"Ultra-fast light-curing resin composite with increased conversion and reduced monomer elution","volume":"30","author":"L D Randolph","year":"2014","journal-title":"Dent Mater"},{"issue":"12","key":"ref25","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.dental.2006.12.011","article-title":"Elution of monomers from two conventional dental composite materials","volume":"23","author":"O Polydorou","year":"2007","journal-title":"Dent 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Sci"},{"issue":"02","key":"ref36","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3390\/jcs4020081","article-title":"Development of chlorhexidine loaded halloysite nanotube based experimental resin composite with enhanced physico-mechanical and biological properties for dental applications","volume":"4","author":"T Barot","year":"2020","journal-title":"J Compos Sci"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"103675","DOI":"10.1016\/j.jmbbm.2020.103675","article-title":"Physicochemical and biological assessment of flowable resin composites incorporated with farnesol loaded halloysite nanotubes for dental applications","volume":"104","author":"T Barot","year":"2020","journal-title":"J Mech Behav Biomed Mater"},{"issue":"07","key":"ref38","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.dental.2004.08.008","article-title":"Adverse effects of human pulps after direct pulp capping with the different components from a total-etch, three-step adhesive system","volume":"21","author":"MdeL Accorinte","year":"2005","journal-title":"Dent Mater"},{"issue":"03","key":"ref39","first-page":"211","article-title":"Pulp response and cytotoxicity evaluation of 2 dentin bonding agents","volume":"32","author":"F F Demarco","year":"2001","journal-title":"Quintessence Int"},{"issue":"06","key":"ref40","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1034\/j.1600-9657.2000.016006240.x","article-title":"Pulp capping with adhesive resin-based composite vs. calcium hydroxide: a review","volume":"16","author":"A H Schuurs","year":"2000","journal-title":"Endod Dent Traumatol"},{"issue":"01","key":"ref41","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/jbm.b.31167","article-title":"HPLC analysis of eluted monomers from two composite resins cured with LED and halogen curing lights","volume":"88","author":"M H Tabatabaee","year":"2009","journal-title":"J Biomed Mater Res B Appl 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