{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:53:44Z","timestamp":1740142424603,"version":"3.37.3"},"reference-count":51,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T00:00:00Z","timestamp":1717718400000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Memory complaints are frequent in older adults and are associated with higher risk of cognitive decline.<\/jats:p><jats:p>\n          Objective\u2003To investigate the functional outcome of individuals with memory complaints followed up at primary care centers.<\/jats:p><jats:p>\n          Methods\u2003Data were collected between 2016 e 2020 in primary health care centers in Brazil. Patients underwent the Brief Cognitive Screening Battery, and the Functional Activities Questionnaire.<\/jats:p><jats:p>\n          Results\u2003The initial sample (2016) comprised 91 individuals classified into those with subjective cognitive decline (SCD, n\u2009=\u200915), mild cognitive impairment (MCI, n\u2009=\u200945), or dementia (n\u2009=\u200931). During follow-up, 8 individuals (8.8% of the initial sample) died and 26 (28.5% of the initial sample) were not found. Fifty-seven participants underwent clinical reassessment. Of 15 individuals with SCD, 7 were not found (46.7%), 4 (26.7%) progressed to MCI, and 4 (26.7%) remained stable. Of 45 individuals with MCI, 11 were not found (24.4%), 2 (4.4%) died, 6 (13.4%) progressed to dementia, 12 (26.7%) regressed to SCD, and 14 (31.1%) remained stable. Of 31 individuals with dementia, 8 were not found (25.8%), 6 (19.4%) died, 2 (6.5%) regressed to SCD, 7 (22.6%) regressed to MCI, and 8 remained stable (25.8%). Clinical improvement was due to the treatment of reversible causes, such as B12 hypovitaminosis and mood disorders. Older age, lower Mini-Mental State Examination, and higher scores of memory complaint, but not the use of benzodiazepines and of proton pump inhibitors, were predictors of functional status.<\/jats:p><jats:p>\n          Conclusion\u2003Despite their limits (short sample size, missing data), these results support the idea that adequate screening, follow-up, and treatment of reversible causes of dementia in primary care are essential.<\/jats:p>","DOI":"10.1055\/s-0044-1787138","type":"journal-article","created":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T23:27:33Z","timestamp":1717802853000},"page":"001-009","source":"Crossref","is-referenced-by-count":0,"title":["Memory complaint in a middle-income country: a four-year longitudinal study in a cohort with low-education"],"prefix":"10.1055","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3726-8353","authenticated-orcid":false,"given":"Marcos Leandro","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Neuroci\u00eancias, Belo Horizonte MG, Brazil."},{"name":"Khronus Sa\u00fade e Educa\u00e7\u00e3o Ltda, Instituto Khronus de Desenvolvimento Humano, Patos de Minas MG, Brazil."},{"name":"Centro Universit\u00e1rio de Patos de Minas, Curso de Medicina, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4786-6990","authenticated-orcid":false,"given":"Paulo","family":"Caramelli","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Neuroci\u00eancias, Belo Horizonte MG, Brazil."},{"name":"Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Cl\u00ednica M\u00e9dica, Belo Horizonte MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4956-7214","authenticated-orcid":false,"given":"Vannessa Marinara de","family":"S\u00e1","sequence":"additional","affiliation":[{"name":"Khronus Sa\u00fade e Educa\u00e7\u00e3o Ltda, Instituto Khronus de Desenvolvimento Humano, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8694-981X","authenticated-orcid":false,"given":"Paulo Henrique Martins","family":"Rocha","sequence":"additional","affiliation":[{"name":"Khronus Sa\u00fade e Educa\u00e7\u00e3o Ltda, Instituto Khronus de Desenvolvimento Humano, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1215-0423","authenticated-orcid":false,"given":"Jo\u00e3o Pedro Gomes de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio de Patos de Minas, Curso de Medicina, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3362-7665","authenticated-orcid":false,"given":"Rafael Pereira de","family":"Amorim","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio de Patos de Minas, Curso de Medicina, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7581-9075","authenticated-orcid":false,"given":"Elvis Vieira da","family":"Silva","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio de Patos de Minas, Curso de Medicina, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2455-3753","authenticated-orcid":false,"given":"Vin\u00edcius Slonsky","family":"Delboni","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio de Patos de Minas, Curso de Medicina, Patos de Minas MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7520-3476","authenticated-orcid":false,"given":"Maira Tonidandel","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Cl\u00ednica M\u00e9dica, Belo Horizonte MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6513-1891","authenticated-orcid":false,"given":"Lu\u00eds Felipe Jos\u00e9 Ravic de","family":"Miranda","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Faculdade de Medicina, Departamento de Cl\u00ednica M\u00e9dica, Belo Horizonte MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5027-9722","authenticated-orcid":false,"given":"Leonardo Cruz","family":"de Souza","sequence":"additional","affiliation":[{"name":"Universidade Federal de 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