{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:16:28Z","timestamp":1792628188814,"version":"4.5.0"},"reference-count":19,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003The history of wounds dates back to the evolution of mankind. Throughout the centuries, management modalities of wounds have undergone drastic changes. With the advent of technology, we have multiple options for wound care, but none of them can be called the gold standard of wound care. Autologous fat grafting (AFG) is one of the most routinely performed procedures in aesthetic surgery. Fat grafting has shown beneficial effects in the healing of wounds. The regenerative potential of autologous fat is contributed by the adipose-derived stem cells present within the stromal vascular fraction, which are capable of differentiating into multiple cell types. This study aims to analyze the usefulness of AFG in cutaneous wound healing.<\/jats:p><jats:p>\n          Materials and Methods\u2003This prospective, study was conducted in our institute between April 2021 and May 2023. Eighteen patients with nonhealing wounds were included in the study. For assessing wound healing all the patients were first managed with conventional dressing for 2 weeks before surgery. After routine preoperative workup, the procedure was performed under local anesthesia in most cases. Fat was harvested from the lower abdomen and after emulsification, was injected into the edge and floor of the ulcer. The dressing was changed on the third postoperative day and the outcome was assessed.<\/jats:p><jats:p>\n          Results\u2003Eighteen patients (M:F ratio 8:1), with a mean age of 35.61\u2009\u00b1\u200912. 64 years (range 10\u201365 years), were included in this study. The most common etiology was trauma (44%), others being postop infection (17%), veno-lymphatic ulcer (17%), burns (11%), insect bite (5%), and trophic ulcer (5%). Majority of the wounds (95%) healed without the need for any extra intervention. The mean period taken for complete wound healing was 5.05 weeks.<\/jats:p><jats:p>\n          Conclusion\u2003Complete wound healing was achieved in majority of the patients without any complications. We recommend the usage of AFG for nonhealing wounds, as the procedure is relatively simple and can be performed after basic training. Larger-scale randomized controlled trials should be conducted to prove their efficacy in the management of complicated wounds.<\/jats:p>","DOI":"10.1055\/s-0044-1787174","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T22:36:35Z","timestamp":1717108595000},"page":"201-207","source":"Crossref","is-referenced-by-count":6,"title":["Utility of Fat Grafting in Chronic Wounds"],"prefix":"10.1055","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4619-6108","authenticated-orcid":false,"given":"Om","family":"Prakash","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheikh Sarfraz","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd","family":"Yaseen","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8294-4683","authenticated-orcid":false,"given":"Indrajith K.","family":"Sudhy","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3813-0803","authenticated-orcid":false,"given":"Pavan K.","family":"Venkateshwar","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. Ranga","family":"Kishore","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"issue":"04","key":"ref1","first-page":"84","article-title":"Factors that impair wound healing","volume":"4","author":"K Anderson","year":"2014","journal-title":"J Am Coll Clin Wound Spec"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"268","DOI":"10.18203\/2349-2902.isj20230266","article-title":"Fat grafting; an adjunct in management of chronic leg ulcers","volume":"10","author":"R Saroha","year":"2023","journal-title":"Int Surg J"},{"issue":"03","key":"ref3","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/0022034509359125","article-title":"Factors affecting wound healing","volume":"89","author":"S Guo","year":"2010","journal-title":"J Dent Res"},{"issue":"01","key":"ref4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.clindermatol.2006.12.005","article-title":"Impaired wound healing","volume":"25","author":"N B Menke","year":"2007","journal-title":"Clin Dermatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"x","DOI":"10.1155\/2013\/413604","article-title":"Chronic leg ulcers: epidemiology, aetiopathogenesis, and management","volume":"2013","author":"S Agale","year":"2013","journal-title":"Ulcers"},{"issue":"24","key":"ref6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.amsu.2017.11.001","article-title":"The science behind autologous fat grafting","volume":"24","author":"E Bellini","year":"2017","journal-title":"Ann Med Surg (Lond)"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"108S","DOI":"10.1097\/01.prs.0000234610.81672.e7","article-title":"Structural fat grafting: more than a permanent 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