{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,25]],"date-time":"2024-12-25T00:10:01Z","timestamp":1735085401949,"version":"3.32.0"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n            Objective\u2003We aimed to examine rates of induction of labor at 39 weeks and cesarean delivery before and after the ARRIVE (A Randomized Trial of Induction Versus Expectant Management) trial stratified by body mass index (BMI; kg\/m2) category.<\/jats:p><jats:p>\n            Study Design\u2003This was a repeated cross-sectional analysis of publicly available U.S. birth certificate data from 2015 to 2021. We limited analyses to nulliparous individuals with a singleton pregnancy, cephalic presentation, without chronic hypertension, diabetes (gestational or pregestational), and fetal anomaly who delivered between 39 and 42 weeks' gestation. The pre-ARRIVE period spanned from August 2016 to July 2018 and the post-ARRIVE period spanned from January 2019 to December 2020. The dissemination period of the ARRIVE trial was from August 2018 to December 2018. Our co-primary outcomes were induction at 39 weeks and cesarean delivery. Our secondary outcomes were overall induction of labor and preeclampsia. We conducted an interrupted time series analysis after stratifying by prepregnancy BMI (&lt;40 or \u226540). Negative binomial regression was used to calculate adjusted incident rate ratios with 95% confidence intervals.<\/jats:p><jats:p>\n            Results\u2003Of 2,122,267 individuals that were included, 2,051,050 had BMI &lt;40 and 71,217 had BMI \u226540. In individuals with BMI &lt;40, the post-ARRIVE period compared to the pre-ARRIVE period was associated with an increased rate of induction of labor at 39 weeks, a decreased rate of cesarean delivery, and an increased rate of overall induction of labor. In individuals with BMI \u226540, the post-ARRIVE period compared to the pre-ARRIVE period was associated with an increased rate of induction of labor at 39 weeks, an increased rate of overall induction of labor and a decreased rate of preeclampsia; however, the decrease in the rate of cesarean delivery was not significant.<\/jats:p><jats:p>\n            Conclusion\u2003An increase in induction of labor at 39 weeks' gestation in individuals with BMI \u226540 was not associated with a decrease in the cesarean delivery rate.<\/jats:p><jats:p>\n            Key Points\n          <\/jats:p>","DOI":"10.1055\/s-0044-1787542","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T23:02:38Z","timestamp":1718060558000},"page":"060-067","source":"Crossref","is-referenced-by-count":0,"title":["Impact of the ARRIVE Trial in Nulliparous Individuals with Morbid Obesity: Interrupted Time Series Analysis"],"prefix":"10.1055","volume":"42","author":[{"given":"Rula","family":"Atwani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Saade","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jim C.","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Business Management, National Sun Yat-Sen University, Kaohsiung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Kawakita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1056\/NEJMoa1800566","article-title":"Labor induction versus expectant management in low-risk nulliparous women","volume":"379","author":"W A Grobman","year":"2018","journal-title":"N Engl J Med"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1016\/j.ajog.2021.11.155","article-title":"Elective induction of labor in nulliparas: has the ARRIVE trial changed obstetric practices and outcomes?","volume":"226","author":"V Souter","year":"2022","journal-title":"Am J Obstet Gynecol"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"590.e1","DOI":"10.1016\/j.ajog.2019.02.017","article-title":"Induction of labor at 39 weeks of gestation versus expectant management for low-risk nulliparous women: a 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Gynecol"},{"issue":"02","key":"ref11","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/01.AOG.0000172422.81496.57","article-title":"Prepregnancy obesity and fetal death: a study within the Danish National Birth Cohort","volume":"106","author":"E A Nohr","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"01","key":"ref16","doi-asserted-by":"crossref","first-page":"B2","DOI":"10.1016\/j.ajog.2018.08.009","article-title":"SMFM Statement on Elective Induction of Labor in Low-Risk Nulliparous Women at Term: the ARRIVE Trial","volume":"221","author":"Society of Maternal-Fetal (SMFM) Publications Committee. Electronic address: pubs@smfm.org","year":"2019","journal-title":"Am J Obstet Gynecol"},{"issue":"04","key":"ref17","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1046\/j.1365-2710.2002.00430.x","article-title":"Segmented regression analysis of interrupted time series studies in medication use research","volume":"27","author":"A K Wagner","year":"2002","journal-title":"J Clin Pharm Ther"},{"key":"ref18","first-page":"348","article-title":"Interrupted time series regression for the evaluation of public health interventions: a tutorial","volume":"46","author":"J Lopez Bernal","year":"2016","journal-title":"Int J Epidemiol"},{"key":"ref19","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-52452-8","volume-title":"Time Series Analysis and Its Applications: With R Examples","author":"R H Shumway","year":"2017"},{"issue":"02","key":"ref20","first-page":"242","article-title":"Effects of the ARRIVE (A Randomized Trial of Induction Versus Expectant Management) Trial on elective induction and obstetric outcomes in term nulliparous patients","volume":"142","author":"E Nethery","year":"2023","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref21","doi-asserted-by":"crossref","first-page":"451.e1","DOI":"10.1016\/j.ajog.2017.05.048","article-title":"Nonmedically indicated induction in morbidly obese women is not associated with an increased risk of cesarean delivery","volume":"217","author":"T Kawakita","year":"2017","journal-title":"Am J Obstet Gynecol"},{"issue":"04","key":"ref22","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.ajog.2003.09.058","article-title":"Obesity, obstetric complications and cesarean delivery rate\u2013a population-based screening study","volume":"190","author":"J L Weiss","year":"2004","journal-title":"Am J Obstet Gynecol"},{"issue":"08","key":"ref23","doi-asserted-by":"crossref","first-page":"e2328274","DOI":"10.1001\/jamanetworkopen.2023.28274","article-title":"Rates of induction of labor at 39 weeks and cesarean delivery following publication of the ARRIVE Trial","volume":"6","author":"R Wood","year":"2023","journal-title":"JAMA Netw Open"}],"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1787542.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T23:31:45Z","timestamp":1735083105000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1787542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,10]]},"references-count":18,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2024,12,24]]},"published-print":{"date-parts":[[2025,1]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1787542","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"type":"print","value":"0735-1631"},{"type":"electronic","value":"1098-8785"}],"subject":[],"published":{"date-parts":[[2024,6,10]]}}}