{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T10:30:47Z","timestamp":1781001047101,"version":"3.54.1"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":63,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["TH Open"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\/Objective\u2003Colonoscopy with polypectomy is an integral component of colorectal cancer screening. There are limited data and consensus on periprocedural anticoagulation management, especially regarding bleeding risk with uninterrupted anticoagulation and thromboembolic risk with interruption. Our aim was to determine the incidence of bleeding and thromboembolic complications among colon screening participants undergoing colonoscopy following implementation of a novel patient care pathway for standardized periprocedural anticoagulation management.<\/jats:p><jats:p>\n          Methods\u2003We conducted a retrospective study including all participants (age 50\u201374) on an oral anticoagulant (e.g., vitamin K antagonists, direct oral anticoagulants) referred to the British Columbia Colon Screening Program for colonoscopy following abnormal fecal immunochemical test in a 6-month period (March\u2013August 2022). Data relating to their specific periprocedural anticoagulant management and colonoscopy results including method of polypectomy were obtained. Primary outcomes were major bleeding and arterial or venous thromboembolic events from time of oral anticoagulant interruption until 14 days of postcolonoscopy. Secondary outcomes included nonmajor and minor bleeding, acute coronary syndrome, emergency room visit, hospital admission, and death due to any cause.<\/jats:p><jats:p>\n          Results\u2003Over the 6-month period, 162 participants completed standardized periprocedural anticoagulation management, colonoscopy\u2009\u00b1\u2009polypectomy, and 14-day follow-up. One (0.6%) had a major bleeding event and one (0.6%) had an arterial thromboembolic event.<\/jats:p><jats:p>\n          Conclusions\u2003A novel patient care pathway for standardized periprocedural anticoagulation management with a multidisciplinary team is associated with low rates of major bleeding and thrombotic complications after colonoscopy with polypectomy.<\/jats:p>","DOI":"10.1055\/s-0044-1787553","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T23:29:51Z","timestamp":1717457391000},"page":"e216-e223","source":"Crossref","is-referenced-by-count":3,"title":["Periprocedural Anticoagulation Management of Patients Undergoing Colonoscopy with Polypectomy"],"prefix":"10.1055","volume":"08","author":[{"given":"Melissa","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chipman T.","family":"Drury","sequence":"first","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"Division of General Internal Medicine, University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Wan","sequence":"first","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"Division of General Internal Medicine, University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J.","family":"Telford","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"Division of Gastroenterology, University of British Columbia, Vancouver, Canada"},{"name":"British Columbia Colon Screening Program, BC Cancer, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,6,3]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1038\/ajg.2017.174","article-title":"Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer","volume":"112","author":"D K Rex","year":"2017","journal-title":"Am J Gastroenterol"},{"issue":"03","key":"ref2","first-page":"381","article-title":"Colonoscopy-related adverse events in patients with abnormal stool-based tests: a systematic review of literature and meta-analysis of outcomes","volume":"117","author":"S Chandan","year":"2022","journal-title":"Am J 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