{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:16:06Z","timestamp":1793121366556,"version":"4.5.0"},"reference-count":82,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Reprod Med"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anti-Mu\u0308llerian hormone (AMH) is secreted by Sertoli cells and is responsible for the regression of M\u00fcllerian ducts in the male fetus as part of the sexual differentiation process. Serum AMH concentrations are at their lowest levels in the first days after birth but increase after the first week, likely reflecting active Sertoli cell proliferation. AMH rises rapidly in concentration in boys during the first month, reaching a peak level at \u223c6 months of age, and it remains high during childhood, then they will slowly decline during puberty, falling to low levels in adulthood. Serum AMH measurement is used by pediatric endocrinologist as a specific marker of immature Sertoli cell number and function during childhood. After puberty, AMH is released especially by the apical pole of the Sertoli cells toward the lumen of the seminiferous tubules, resulting in higher levels in the seminal plasma than in the serum. Recently, AMH has received increasing attention in research on male fertility\u2013related disorders. This article reviews and summarizes the potential contribution of serum AMH measurement in different male fertility\u2013related disorders.<\/jats:p>","DOI":"10.1055\/s-0044-1787687","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T22:57:27Z","timestamp":1719269847000},"page":"005-014","source":"Crossref","is-referenced-by-count":13,"title":["Role of Anti-Mu\u0308llerian Hormone in Male Reproduction and Sperm Motility"],"prefix":"10.1055","volume":"42","author":[{"given":"Hamza","family":"Benderradji","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetology, and Metabolism, CHU Lille, Lille, France"},{"name":"Inserm, CHU Lille, Unit 1172, Lille Neuroscience & Cognition (LilNCog), University of Lille, Lille, France"},{"name":"Department of Andrology, Urology and Renal Transplantation, University of Lille, CHU Lille, Lille University Hospital, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Prasivoravong","sequence":"additional","affiliation":[{"name":"Department of Andrology, Urology and Renal Transplantation, University of Lille, CHU Lille, Lille University Hospital, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Marcelli","sequence":"additional","affiliation":[{"name":"Department of Andrology, Urology and Renal Transplantation, University of Lille, CHU Lille, Lille University Hospital, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Leroy","sequence":"additional","affiliation":[{"name":"Department of Andrology, Urology and Renal Transplantation, University of Lille, CHU Lille, Lille University Hospital, Lille, France"},{"name":"Department of Pediatric Endocrinology, Reference Centre for Genital Development Abnormalities, University of Lille, CHU Lille, DevGen, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,6,24]]},"reference":[{"issue":"07","key":"ref1","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1210\/clinem\/dgac218","article-title":"Defining reference ranges for serum anti-M\u00fcllerian hormone on a large cohort of normozoospermic adult men highlights new potential physiological functions of AMH on FSH secretion and sperm motility","volume":"107","author":"H Benderradji","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"ref2","doi-asserted-by":"crossref","first-page":"5357","DOI":"10.1210\/jc.2010-1207","article-title":"Changes in anti-M\u00fcllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years","volume":"95","author":"L Aksglaede","year":"2010","journal-title":"J Clin Endocrinol 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