{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:47:50Z","timestamp":1782841670857,"version":"3.54.5"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nucl Med"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Aim\u2003The imaging of Meckel's diverticulum (MD) is based of accumulation of Tc-99m pertechnetate in the ectopic gastric mucosa (EGM) content. Although the diagnostic accuracy of this imaging modality is high, there are some overlap patients with coexisting gastrointestinal bleeding and false positive causes hampering diagnostic power. The aim of this study was to evaluate the possible contribution of single-photon emission computed tomography\/computed tomography (SPECT\/CT) in EGM-MD diagnosis and to determine the indication of this additional imaging modality.<\/jats:p><jats:p>\n          Materials and Methods\u2003Fifty-two pediatric patients (24 girls, 28 boys; mean age: 8.06\u2009\u00b1\u20095.22 years old) who have suspicion of MD and referred for scintigraphy were evaluated retrospectively. Additional SPECT\/CT were performed to selected five cases among the group. The results of the scintigraphy as well as SPECT\/CT were compared with endoscopy, pathology, and\/or follow-up results.<\/jats:p><jats:p>\n          Results\u2003There were 9 patients with equivocal study results, 12 positive results, and the others were considered negative MD scintigraphy. One patient was out of follow-up and 10 patients underwent surgery. Only one single patient was negative during surgery but scintigraphy was also negative. The diagnostic sensitivity, specificity, and accuracy were 100, 95, and 96%, respectively. Among five patients with SPECT\/CT results one patient was diagnosed by only SPECT\/CT who had EGM in duplication cyst, one equivocal patient was diagnosed as descending colon bleeding, and one patient's lesion was clearly delineated by SPECT\/CT.<\/jats:p><jats:p>\n          Conclusion\u2003SPECT\/CT has clear advantage over standard planar scintigraphy imaging in EGM-MD determination. This modality might decrease equivocal and false positive results but this issue has to be addressed with further studies.<\/jats:p>","DOI":"10.1055\/s-0044-1787719","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T05:07:01Z","timestamp":1718168821000},"page":"176-179","source":"Crossref","is-referenced-by-count":4,"title":["SPECT\/CT in the Diagnosis of Ectopic Gastric Mucosa-Meckel's Diverticulum"],"prefix":"10.1055","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3274-5790","authenticated-orcid":false,"given":"Zehra P\u0131nar","family":"Ko\u00e7","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Mersin University, Mersin, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u0131nar Pelin","family":"\u00d6zcan","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Mersin University, Mersin, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferah","family":"Tuncel","sequence":"additional","affiliation":[{"name":"Department of Pathology, Mersin University, Mersin, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caner","family":"\u0130sbir","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Mersin University, Mersin, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Usta","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology, Mersin University, Mersin, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"issue":"09","key":"ref1","doi-asserted-by":"crossref","first-page":"300060520955055","DOI":"10.1177\/0300060520955055","article-title":"Meckel's diverticulum with polypoid hyperplasia of ectopic gastric mucosa diagnosed by double-balloon enteroscopy and single-photon emission computed tomography\/computed tomography","volume":"48","author":"J Yang","year":"2020","journal-title":"J Int Med Res"},{"issue":"10","key":"ref2","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1177\/014107680609901011","article-title":"Meckel's diverticulum: a systematic review","volume":"99","author":"J Sagar","year":"2006","journal-title":"J R Soc Med"},{"issue":"09","key":"ref3","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1007\/s00268-004-7512-3","article-title":"Meckel's diverticulum: comparison of incidental and symptomatic cases","volume":"28","author":"K E Bani-Hani","year":"2004","journal-title":"World J Surg"},{"issue":"11","key":"ref4","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1097\/00007611-200295110-00022","article-title":"Gastrointestinal bleeding in adult patients with Meckel's diverticulum: the role of technetium 99m pertechnetate scan","volume":"95","author":"S Lin","year":"2002","journal-title":"South Med J"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/RLU.0000000000003938","article-title":"An atypical case of Meckel's diverticulum assessed by SPECT\/CT imaging","volume":"47","author":"G S Mittl","year":"2022","journal-title":"Clin Nucl Med"},{"issue":"43","key":"ref6","doi-asserted-by":"crossref","first-page":"e13004","DOI":"10.1097\/MD.0000000000013004","article-title":"Spontaneous perforation and intraabdominal abscess due to Meckel's diverticulum revealed on SPECT\/CT with 99m-technetium pertechnetate: a case report","volume":"97","author":"Y Zhu","year":"2018","journal-title":"Medicine (Baltimore)"},{"issue":"01","key":"ref7","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1186\/s40064-016-2928-4","article-title":"Incremental value of SPECT\/CT in detection of Meckel's diverticulum in a 10-year-old child","volume":"5","author":"Q Xie","year":"2016","journal-title":"Springerplus"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4103\/0972-3919.112738","article-title":"Promising role of single photon emission computed tomography\/computed tomography in Meckel's scan","volume":"27","author":"A Jain","year":"2012","journal-title":"Indian J Nucl Med"},{"issue":"04","key":"ref9","doi-asserted-by":"crossref","first-page":"361","DOI":"10.4103\/ijnm.IJNM_25_17","article-title":"Tubular intestinal duplication harboring gastric ectopia accurately diagnosed by Tc-99m pertechnetate single-photon emission computed tomography\/computed tomography Meckel's scan","volume":"32","author":"I Spyridakis","year":"2017","journal-title":"Indian J Nucl Med"},{"issue":"03","key":"ref10","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/RLU.0000000000002917","article-title":"Radioguided surgery for Meckel diverticulum: nuclear medicine aspects","volume":"45","author":"E Medaer","year":"2020","journal-title":"Clin Nucl Med"},{"issue":"25","key":"ref11","doi-asserted-by":"crossref","first-page":"e1017","DOI":"10.1097\/MD.0000000000001017","article-title":"Rescue radioguided laparoscopy surgery for Meckel's diverticulum: technical notes","volume":"94","author":"J Deus","year":"2015","journal-title":"Medicine (Baltimore)"},{"issue":"03","key":"ref12","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s12519-010-0227-7","article-title":"SPECT-CT image fusion could enhance Meckel scan","volume":"6","author":"P Schneider","year":"2010","journal-title":"World J Pediatr"},{"issue":"02","key":"ref13","doi-asserted-by":"crossref","first-page":"252","DOI":"10.2967\/jnumed.115.157289","article-title":"Gastrointestinal bleeding scintigraphy in the early 21st century","volume":"57","author":"E Grady","year":"2016","journal-title":"J Nucl 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