{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:45:42Z","timestamp":1751503542550,"version":"3.37.3"},"reference-count":51,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Appl Clin Inform"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Nurses adjust intravenous nitroglycerin infusions to provide acute relief for angina by manually increasing or decreasing the dosage. However, titration can pose challenges, as excessively high doses can lead to hypotension, and low doses may result in inadequate pain relief. Clinical decision support systems (CDSSs) that predict changes in blood pressure for nitroglycerin dose adjustments may assist nurses with titration.<\/jats:p><jats:p>\n          Objective\u2003This study aimed to design a user interface for a CDSS for nitroglycerin dose titration (Nitroglycerin Dose Titration Decision Support System [nitro DSS]).<\/jats:p><jats:p>\n          Methods\u2003A user-centered design (UCD) approach, consisting of an initial qualitative study with semistructured interviews to identify design specifications for prototype development, was used. This was followed by three iterative rounds of usability testing. Nurses with experience titrating nitroglycerin infusions in coronary care units participated.<\/jats:p><jats:p>\n          Results\u2003A total of 20 nurses participated, including 7 during the qualitative study and 15 during usability testing (2 nurses participated in both phases). Analysis of the qualitative data revealed four themes for the interface design to be (1) clear and consistent, (2) vigilant, (3) interoperable, and (4) reliable. The major elements of the final prototype included a feature for viewing the predicted and actual blood pressure over time to determine the reliability of the predictions, a drop-down option to report patient side effects, a feature to report reasons for not accepting the prediction, and a visual alert indicating any systolic blood pressure predictions below 90\u2009mm Hg. Nurses' ratings on the questionnaires indicated excellent usability and acceptability of the final nitro DSS prototype.<\/jats:p><jats:p>\n          Conclusion\u2003This study successfully applied a UCD approach to collaborate with nurses in developing a user interface for the nitro DSS that supports the clinical decision-making of nurses titrating nitroglycerin.<\/jats:p>","DOI":"10.1055\/s-0044-1787755","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T23:13:33Z","timestamp":1721862813000},"page":"583-599","source":"Crossref","is-referenced-by-count":3,"title":["Designing the User Interface of a Nitroglycerin Dose Titration Decision Support System: User-Centered Design Study"],"prefix":"10.1055","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6500-0456","authenticated-orcid":false,"given":"Navpreet","family":"Kamboj","sequence":"additional","affiliation":[{"name":"Lawrence S. 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