{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T07:38:17Z","timestamp":1772609897744,"version":"3.50.1"},"reference-count":28,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ortop (Sao Paulo)"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Resumo<\/jats:title><jats:p>\n          Objetivo\u2003Analisar o trofismo muscular e a de interleucina-6 no m\u00fasculo b\u00edceps braquial de ratas com les\u00e3o medular cervical incompleta tratados com estimula\u00e7\u00e3o el\u00e9trica neuromuscular (EENM).<\/jats:p><jats:p>\n          M\u00e9todos\u2003Ratas adultas foram submetidas \u00e0 hemissec\u00e7\u00e3o da medula espinal em C5-C7 e a um protocolo de EENM de 5 semanas. O trofismo do b\u00edceps braquial foi avaliado pela rela\u00e7\u00e3o peso muscular\/peso corporal e an\u00e1lise histol\u00f3gica. A express\u00e3o de interleucina-6 no b\u00edceps braquial foi medida usando ensaio de imunoabsor\u00e7\u00e3o enzim\u00e1tica.<\/jats:p><jats:p>\n          Resultados\u2003O grupo tratado com EENM apresentou preserva\u00e7\u00e3o do trofismo muscular, assim como preven\u00e7\u00e3o da redu\u00e7\u00e3o dos n\u00edveis de interleucina-6.<\/jats:p><jats:p>\n          Conclus\u00e3o\u2003A les\u00e3o da medula espinal causa atrofia muscular e diminui a express\u00e3o de interleucina-6. Essas altera\u00e7\u00f5es s\u00e3o parcialmente prevenidas pela EENM. Os resultados sugerem um poss\u00edvel mecanismo de a\u00e7\u00e3o da EENM e ressaltam o uso cl\u00ednico desta ferramenta terap\u00eautica.<\/jats:p>","DOI":"10.1055\/s-0044-1787767","type":"journal-article","created":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T22:44:09Z","timestamp":1725489849000},"page":"e526-e531","source":"Crossref","is-referenced-by-count":1,"title":["A estimula\u00e7\u00e3o el\u00e9trica previne a atrofia muscular e a diminui\u00e7\u00e3o da interleucina-6 em m\u00fasculos paralisados ap\u00f3s les\u00e3o da medula espinal em ratos"],"prefix":"10.1055","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4355-4428","authenticated-orcid":false,"given":"Nicolas A. M. 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