{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:12:32Z","timestamp":1784297552855,"version":"3.55.0"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"S 01","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Plast Surg"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Dermal substitutes offer a valuable tool in soft-tissue reconstruction, reducing the need for donor site tissue and its associated complications. However, conventional approaches often require multiple surgeries. This study aimed to compare the effectiveness of a single-stage procedure combining dermal substitute and skin grafting with hyperbaric oxygen (HBO) therapy to the standard multistage protocol.<\/jats:p><jats:p>\n          Materials and Methods\u2003A comparative study was conducted from January 2022 to December 2023. The medical records of 24 patients who underwent soft-tissue reconstruction were reviewed. Patients were categorized into two groups based on whether they received HBO therapy (HBO group) or followed the standard multistage protocol (control group). Outcomes were compared between the groups.<\/jats:p><jats:p>\n          Results\u2003The study included 18 males and 6 females with an average age of 43 years (range: 5\u201391 years). Underlying medical conditions included diabetes mellitus (n\u2009=\u200911) and peripheral vascular disease (n\u2009=\u20092). Wounds were due to various causes, including necrotizing fasciitis (n\u2009=\u20092), trauma (n\u2009=\u200910), diabetic ulcers (n\u2009=\u20096), postburn hypertrophic scars\/contractures (n\u2009=\u20093), chronic ulcers (n\u2009=\u20091), and sternal wound dehiscence (n\u2009=\u20091). All the patients achieved successful wound closure with dermal substitute application, eliminating the need for additional surgery. Notably, the group receiving HBO therapy experienced a shorter overall hospital stay compared with the standard multistage group.<\/jats:p><jats:p>\n          Conclusion\u2003This study demonstrates the effectiveness of dermal substitutes in soft-tissue reconstruction. Furthermore, the addition of HBO therapy in a single-stage procedure appears beneficial for successful outcomes, potentially reducing hospital stay compared with the traditional multistage approach.<\/jats:p>","DOI":"10.1055\/s-0044-1788592","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T23:13:47Z","timestamp":1721344427000},"page":"S92-S99","source":"Crossref","is-referenced-by-count":3,"special_numbering":"S","title":["Evaluating Hyperbaric Oxygen Therapy to Improve Single-Stage Dermal Substitute and Skin Grafting: A Comparative Study"],"prefix":"10.1055","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4660-294X","authenticated-orcid":false,"given":"Pradeoth Mukundan","family":"Korambayil","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery and Burns, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemang Arvind","family":"Sanghvi","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery and Burns, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinoth Kumar","family":"Dilliraj","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Vijaya Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanth Varkey","family":"Ambookan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery and Burns, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0305-4179(97)88485-9","article-title":"Reconstruction of burn deformity using 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