{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T13:28:38Z","timestamp":1780147718689,"version":"3.54.0"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T00:00:00Z","timestamp":1729814400000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Sudden sensorineural hearing loss (SSNHL) is defined as a rapid sensation of hearing impairment in one or both ears. Based on its personal impact on patients, the present study advances the analysis of new treatments for the prompt recognition and management of SSNHL, with higher chances of improvements in terms of hearing recovery and quality of life of the patients.<\/jats:p><jats:p>\n          Objective\u2003To describe the intratympanic (IT) corticoid infiltration technique, to demonstrate the efficacy of betamethasone injection as a sequential treatment in patients whose initial systemic steroid treatment failed, as well as to compare its use in different treatment periods.<\/jats:p><jats:p>\n          Methods\u2003The present clinical trial was conducted with 37 patients referred to our office with the diagnosis of SSNHL, from September 2019 to May 2022, who provided informed consent to participate.<\/jats:p><jats:p>\n          Results\u2003Even dividing the analysis of increasing the pure tone average (PTA) or speech recognition threshold (SRT) between the difference into initiation of the salvage therapy in up to 15 days of the sudden deafness event, and between 15 days and 3 months of the event, we did not find any difference in hearing improvement.<\/jats:p><jats:p>\n          Conclusion\u2003Intratympanic corticosteroid therapy is prescribed when conventional therapy fails or when there is a limitation to the use of corticosteroids due to the presence of systemic disorders. As such, new drugs, such as bethametasone, are studied and show promising results.<\/jats:p>","DOI":"10.1055\/s-0044-1788779","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T22:30:22Z","timestamp":1729895422000},"page":"e650-e656","source":"Crossref","is-referenced-by-count":1,"title":["Results of a New Treatment Protocol for Sudden Sensorineural Hearing Loss Using Betamethasone for Intratympanic Therapy"],"prefix":"10.1055","volume":"28","author":[{"given":"Paula Tardim","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, School of Medicine, Hospital das Cl\u00ednicas, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Almeida","sequence":"additional","affiliation":[{"name":"Department of Otology, Funda\u00e7\u00e3o Otorrinolaringologia, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3749-4684","authenticated-orcid":false,"given":"Ricardo Ferreira","family":"Bento","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, School of Medicine, Hospital das Cl\u00ednicas, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,10,25]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0030-6665(20)30362-5","article-title":"Sudden sensorineural hearing loss","volume":"29","author":"G B Hughes","year":"1996","journal-title":"Otolaryngol Clin North Am"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12070-010-0049-x","article-title":"Sudden sensorineural hearing loss: an otologic emergency","volume":"64","author":"H 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