{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:45:35Z","timestamp":1791492335319,"version":"4.3.4"},"reference-count":75,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin Musculoskelet Radiol"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Artificial intelligence (AI) has significantly impacted the field of medical imaging, particularly in diagnosing and managing metabolic bone diseases (MBDs) such as osteoporosis and osteopenia, Paget's disease, osteomalacia, and rickets, as well as rare conditions such as osteitis fibrosa cystica and osteogenesis imperfecta. This article provides an in-depth analysis of AI techniques used in imaging these conditions, recent advancements, and their clinical applications. It also explores ethical considerations and future perspectives. Through comprehensive examination and case studies, we highlight the transformative potential of AI in enhancing diagnostic accuracy, improving patient outcomes, and contributing to personalized medicine. By integrating AI with existing imaging techniques, we can significantly enhance the capabilities of medical imaging in diagnosing, monitoring, and treating MBDs. We also provide a comprehensive overview of the current state, challenges, and future prospects of AI applications in this crucial area of health care.<\/jats:p>","DOI":"10.1055\/s-0044-1789218","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T22:30:29Z","timestamp":1729031429000},"page":"610-619","source":"Crossref","is-referenced-by-count":4,"title":["Artificial Intelligence Applications for Imaging Metabolic Bone Diseases"],"prefix":"10.1055","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5827-0562","authenticated-orcid":false,"given":"Amanda","family":"Isaac","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6262-1799","authenticated-orcid":false,"given":"Asli Irmak","family":"Akdogan","sequence":"additional","affiliation":[{"name":"Ataturk Training and Research Hospital, Izmir Katip \u00c7elebi University, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danoob","family":"Dalili","sequence":"additional","affiliation":[{"name":"Epsom and St. Helier Hospitals, Surrey, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuran","family":"Saber","sequence":"additional","affiliation":[{"name":"Pamukkale University, Denizli, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Drobny","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Guglielmi","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli studi di Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Modat","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Bazzocchi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Mediche e Chirurgiche, Bologna University, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"issue":"04","key":"ref1","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1055\/s-0042-1754340","article-title":"Imaging of metabolic bone diseases: the spine view, Part I","volume":"26","author":"A Bazzocchi","year":"2022","journal-title":"Semin Musculoskelet Radiol"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1055\/s-0042-1754341","article-title":"Imaging of metabolic bone diseases: the spine view, Part II","volume":"26","author":"M P Aparisi G\u00f3mez","year":"2022","journal-title":"Semin Musculoskelet Radiol"},{"issue":"09","key":"ref4","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1002\/jbmr.3118","article-title":"Population-wide impact of non-hip non-vertebral fractures on mortality","volume":"32","author":"T Tran","year":"2017","journal-title":"J Bone Miner Res"},{"issue":"10","key":"ref5","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.3390\/medicina58101431","article-title":"Vertebral augmentation: is it time to get past the pain? 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