{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T04:31:51Z","timestamp":1768883511045,"version":"3.49.0"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"09","license":[{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The coronavirus disease 2019 (COVID-19) pandemic has had a profound global impact, raising concerns about its long-term effects, particularly neurological complications. While studies have highlighted such complications in adults, there is a paucity of research focusing on children.<\/jats:p><jats:p>\n          Objective\u2003To examine the medium- to long-term neurological and cognitive symptoms in 18 year old children and below with positive versus negative COVID-19 antigens and to identify the probable risk factors to promote specific health actions.<\/jats:p><jats:p>\n          Methods\u2003An observational study was carried out to determine neurological symptoms in the medium and long terms after COVID 19. A random sample of 124 children, both symptomatic or asymptomatic, tested positive or negative for COVID-19 through swab tests.<\/jats:p><jats:p>\n          Results\u2003Neurological symptoms were assessed between 6 to 12 months and 2 years after the infection. Acute symptoms, including headache, anosmia, ageusia, and myalgia, were observed in more than 20% of the children, but they generally resolved within 6 to 12 months. Persistent functional difficulties, such as in studying, paying attention, and socializing, were reported in 3% of the cases. Behavioral symptoms at baseline were noted in 7.8% of children, but they were remitted in most cases, except for those with prior involvement.<\/jats:p><jats:p>\n          Conclusion\u2003These findings underscore the need for continued monitoring of children following COVID-19 infection and the importance of tailored health interventions.<\/jats:p>","DOI":"10.1055\/s-0044-1789224","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T22:43:58Z","timestamp":1727217838000},"page":"001-007","source":"Crossref","is-referenced-by-count":1,"title":["Impact on the nervous system of long COVID-19 infection in children"],"prefix":"10.1055","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8448-2611","authenticated-orcid":false,"given":"Nora","family":"Granana","sequence":"additional","affiliation":[{"name":"Hospital General de Agudos Carlos G. Durand, Departmento de Pediatr\u00eda, Buenos Aires, Argentina."},{"name":"Ministerio de Salud, Programa de Orientaci\u00f3n Temprana y Concientizaci\u00f3n de Trastornos del Desarrollo y en el Espectro Autista, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3605-6087","authenticated-orcid":false,"given":"Adriana","family":"Tarulla","sequence":"additional","affiliation":[{"name":"Ministerio de Salud, Programa de Neurociencias, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6983-1430","authenticated-orcid":false,"given":"Ismael","family":"Calandri","sequence":"additional","affiliation":[{"name":"Ministerio de Salud, Programa de Neurociencias, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2668-5155","authenticated-orcid":false,"given":"Analia De","family":"Carli","sequence":"additional","affiliation":[{"name":"Hospital Ramos Mej\u00eda, Programa de Salud Escolar, Buenos Aires, Argentina."},{"name":"Ministerio de Salud, Programa de Salud Escolar, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3655-9925","authenticated-orcid":false,"given":"Belen","family":"Rivas","sequence":"additional","affiliation":[{"name":"Hospital Ramos Mej\u00eda, Programa de Salud Escolar, Buenos Aires, Argentina."},{"name":"Ministerio de Salud, Programa de Salud Escolar, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6304-9086","authenticated-orcid":false,"given":"Jose Maria","family":"Festa","sequence":"additional","affiliation":[{"name":"Hospital Ramos Mej\u00eda, Programa de Salud Escolar, Buenos Aires, Argentina."},{"name":"Ministerio de Salud, Programa de Salud Escolar, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4398-5043","authenticated-orcid":false,"given":"Susana","family":"Vacirca","sequence":"additional","affiliation":[{"name":"Ministerio de Salud, Programa de Salud Escolar, Buenos Aires, Argentina."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3628-336X","authenticated-orcid":false,"given":"Mar\u00eda","family":"Lis","sequence":"additional","affiliation":[{"name":"Hospital General de Agudos Carlos G. 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