{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:38:43Z","timestamp":1786963123493,"version":"build-2736575974"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Angiol"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Acute kidney injury (AKI) is among the most serious of the common postoperative complications of cardiac surgeries, which can increase the short- and long-term morbidity and mortality of patients. This study aimed to examine possible risk factors that lead to AKI. We sought to compare our AKI rates to national averages in coronary artery bypass grafting (CABG) reported by the Society of Thoracic Surgeons (STS). We reviewed our institution's data for renal failure in CABG procedures performed between January 1, 2020, and June 30, 2023. From the database, we identified 1,068 CABG patients and reviewed demographics, nonmodifiable conditions, and modifiable risk factors. The STS database uses the Risk, Injury, Failure, Loss, and End-stage renal disease definition for renal failure. Of our patient sample, 14 (1.3%) experienced renal failure. The national rate for AKI after isolated CABG was 1.9% in 2023. Chronic lung disease was a risk factor for AKI development. The mean perfusion, cross-clamp, ventilator times, and hospital stay increased in AKI patients. All patients who suffered from AKI had undergone perioperative blood transfusion. Our single-center experience with renal failure is slightly better than the national average. In our population, chronic lung disease and lower preoperative ejection fractions were associated with increased rates of AKI. Modifiable risk factors in our population included perioperative blood transfusion and increased perfusion\/cross-clamp times. Lastly, AKI patients spent longer time on ventilators, increased lengths of stay, and increased postoperative mortality.<\/jats:p>","DOI":"10.1055\/s-0044-1791545","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T23:06:57Z","timestamp":1728342417000},"page":"051-055","source":"Crossref","is-referenced-by-count":2,"title":["Acute Kidney Injury after Isolated Coronary Bypass Surgery"],"prefix":"10.1055","volume":"34","author":[{"given":"John C.","family":"Slaughter","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Medicine, Lexington, Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel L.","family":"Davenport","sequence":"additional","affiliation":[{"name":"Division of Healthcare Outcomes and Optimal Patient Services, University of Kentucky, Lexington, Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibu P.","family":"Saha","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, University of Kentucky, Lexington, Kentucky"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"issue":"17","key":"ref1","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1056\/NEJMoa0902413","article-title":"Intensity of continuous renal-replacement therapy in critically ill patients","volume":"361","author":"R Bellomo","year":"2009","journal-title":"N Engl J Med"},{"key":"ref2","volume-title":"Cardiac surgery","author":"B Senst","year":"2023"},{"issue":"02","key":"ref3","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1177\/039139880803100209","article-title":"The epidemiology of cardiac surgery-associated acute kidney injury","volume":"31","author":"E A Hoste","year":"2008","journal-title":"Int J Artif Organs"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1053\/j.jvca.2019.08.042","article-title":"Transesophageal echocardiography, acute kidney injury, and length of hospitalization among adults undergoing coronary artery bypass graft surgery","volume":"34","author":"E J MacKay","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1053\/j.jvca.2021.11.036","article-title":"The association between acute kidney injury and mortality after coronary artery bypass grafting was similar in women and men","volume":"36","author":"J Bell","year":"2022","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2147\/IJNRD.S167477","article-title":"Acute kidney injury after cardiac surgery: prevalence, impact and management challenges","volume":"12","author":"M Vives","year":"2019","journal-title":"Int J Nephrol Renovasc Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/S0140-6736(11)61454-2","article-title":"Acute kidney injury","volume":"380","author":"R Bellomo","year":"2012","journal-title":"Lancet"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"R16","DOI":"10.1186\/cc9960","article-title":"Clinical accuracy of RIFLE and Acute Kidney Injury Network (AKIN) criteria for acute kidney injury in patients undergoing cardiac surgery","volume":"15","author":"L Englberger","year":"2011","journal-title":"Crit Care"},{"key":"ref9","first-page":"S1","article-title":"K\/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification","volume":"39","author":"National Kidney Foundation","year":"2002","journal-title":"Am J Kidney Dis"},{"issue":"06","key":"ref11","doi-asserted-by":"crossref","first-page":"677","DOI":"10.7326\/0003-4819-84-6-677","article-title":"Renal failure after open heart surgery","volume":"84","author":"J G Bhat","year":"1976","journal-title":"Ann Intern Med"},{"issue":"02","key":"ref12","first-page":"85","article-title":"Acute kidney injury: definition, pathophysiology and clinical phenotypes","volume":"37","author":"K Makris","year":"2016","journal-title":"Clin Biochem Rev"},{"issue":"09","key":"ref13","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1111\/aas.12758","article-title":"Renal recovery and long-term survival following acute kidney injury after coronary artery surgery: a nationwide study","volume":"60","author":"S Helgadottir","year":"2016","journal-title":"Acta Anaesthesiol Scand"},{"issue":"06","key":"ref14","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1097\/ALN.0000000000004734","article-title":"Acute kidney injury after cardiac surgery: prediction, prevention, and management","volume":"139","author":"S R Cheruku","year":"2023","journal-title":"Anesthesiology"},{"issue":"09","key":"ref15","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1007\/s11255-019-02173-7","article-title":"Prediction model for acute kidney injury after coronary artery bypass grafting: a retrospective study","volume":"51","author":"Z Yue","year":"2019","journal-title":"Int Urol Nephrol"},{"issue":"23","key":"ref16","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1161\/CIRCULATIONAHA.114.010622","article-title":"Acute kidney injury after coronary artery bypass grafting and long-term risk of end-stage renal disease","volume":"130","author":"L Ryd\u00e9n","year":"2014","journal-title":"Circulation"},{"issue":"04","key":"ref17","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1161\/CIRCULATIONAHA.108.786913","article-title":"Acute kidney injury after cardiac surgery: focus on modifiable risk factors","volume":"119","author":"K Karkouti","year":"2009","journal-title":"Circulation"},{"key":"ref18","first-page":"5605634","article-title":"Are there modifiable risk factors to improve AKI?","volume":"2017","author":"S Nie","year":"2017","journal-title":"BioMed Res Int"},{"key":"ref19","volume-title":"Acute kidney injury","author":"A Goyal","year":"2024"},{"issue":"11","key":"ref20","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1093\/ndt\/gfy178","article-title":"Acute kidney injury following coronary revascularization procedures in patients with advanced CKD","volume":"34","author":"A Gaipov","year":"2019","journal-title":"Nephrol Dial Transplant"},{"issue":"08","key":"ref21","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1056\/NEJMoa2403769","article-title":"A randomized trial of intravenous amino acids for kidney protection","volume":"391","author":"G Landoni","year":"2024","journal-title":"N Engl J Med"}],"container-title":["International Journal of Angiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1791545.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:29:09Z","timestamp":1739320149000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1791545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,7]]},"references-count":20,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2025,2,11]]},"published-print":{"date-parts":[[2025,3]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1791545","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1061-1711","1615-5939"],"issn-type":[{"value":"1061-1711","type":"print"},{"value":"1615-5939","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,7]]}}}