{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:40:26Z","timestamp":1738370426586,"version":"3.35.0"},"reference-count":38,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Various factors have been reported to affect the rates of success after tympanoplasty, among them, myringosclerosis. However, there are few studies focusing only on the effect of myringosclerotic plaque removal on tympanoplasty outcomes.<\/jats:p><jats:p>\n          Objective\u2003To compare the outcome of tympanoplasty in perforated eardrums with and without myringosclerosis.<\/jats:p><jats:p>\n          Methods\u2003The study included patients aged between 21 and 53 years diagnosed at the outpatient department with inactive mucosal chronic otitis media. The sample was divided into the case group, which included subjects with tympanic membrane perforation and myringosclerosis, and the control group, which included subjects with tympanic membrane perforation only, without myringosclerosis. We assessed the audiological findings of the patients before and after surgery, as well as hearing gain, graft uptake, and residual perforation\/reperforation.<\/jats:p><jats:p>\n          Results\u2003No significant relationships were observed involving the age or sex of the patient and the closure rate or hearing gain, neither between the location of the perforation and graft uptake. Graft uptake was higher in patients with perforation size\u2009&lt;\u200950%. The graft uptake and hearing gain were higher in the case group.<\/jats:p><jats:p>\n          Conclusion\u2003The removal of sclerotic plaques increases the surface of the raw area created by subepithelial excision of the myringosclerotic plaques, leading to a high rate of surgical success for the closure of tympanic membrane defects with coexisting myringosclerosis.<\/jats:p>","DOI":"10.1055\/s-0044-1791730","type":"journal-article","created":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:01:51Z","timestamp":1738368111000},"page":"001-009","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Graft Uptake in Perforated Eardrums with and without Myringosclerosis: A Prospective Case-control Study in a Tertiary Centre"],"prefix":"10.1055","volume":"29","author":[{"given":"Ayaz","family":"Rehman","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6732-6679","authenticated-orcid":false,"given":"Faizah Ashfah Latief","family":"Deva","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asef Ahmad","family":"Wani","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majid","family":"Masoodi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashir","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Owais","family":"Makhdoomi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, SKIMS Medical College and Hospital, Srinagar, Jammu and Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"issue":"85","key":"ref1","first-page":"99","article-title":"Evaluation of Factors Affecting the Surgical Outcome in Tympanoplasty","volume":"28","author":"M Naderpour","year":"2016","journal-title":"Iran J Otorhinolaryngol"},{"issue":"168","key":"ref2","first-page":"180","article-title":"Frequency dependence of hearing loss with perforations","volume":"46","author":"C L Bhusal","year":"2007","journal-title":"JNMA J Nepal Med Assoc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0165-5876(97)00147-X","article-title":"Epidemiology and pathogenesis of chronic suppurative otitis media: implications for prevention and treatment","volume":"42","author":"C D Bluestone","year":"1998","journal-title":"J Pediatr Otorhinolaryngol."},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1590\/S1808-86942011000200013","article-title":"Evaluation of the organic and functional results of tympanoplasties through a retro-auricular approach at a medical residency unit","volume":"77","author":"J CBD Lima","year":"2011","journal-title":"Braz J Otorhinolaryngol"},{"key":"ref5","volume-title":"Manual of ear surgery. 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A Clinical Study of Hearing Outcome after Type I Tympanoplasty","volume":"3","author":"K Jain","year":"2016","journal-title":"Int Arch Integr Med."},{"issue":"05","key":"ref29","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1046\/j.1365-2273.2002.00590.x","article-title":"Myringoplasty: does the size of the perforation matter?","volume":"27","author":"P Lee","year":"2002","journal-title":"Clin Otolaryngol Allied Sci"},{"issue":"09","key":"ref30","first-page":"973","article-title":"Myringoplasty: impact of perforation size on closure and audiological improvement","volume":"123","author":"J D Wasson","year":"2009","journal-title":"J Laryngol Rhinol Otol"},{"issue":"06","key":"ref31","doi-asserted-by":"crossref","first-page":"2639","DOI":"10.1007\/s00405-023-07831-2","article-title":"Factors influencing successful reconstruction of tympanic membrane perforations: a systematic review and meta-analysis","volume":"280","author":"K Ill\u00e9s","year":"2023","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"08","key":"ref32","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.ijporl.2005.02.016","article-title":"Tympanoplasty type I in children\u2013an evaluative study","volume":"69","author":"G B Singh","year":"2005","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"02","key":"ref33","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.otohns.2006.10.036","article-title":"Tympanometric volume: a predictor of success of tympanoplasty in children","volume":"136","author":"D Merenda","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"01","key":"ref34","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2399\/jmu.2015001003","article-title":"Factors that may affect graft success in tympanoplasty with mastoidectomy","volume":"5","author":"V Yurttafl","year":"2015","journal-title":"ENT Updates"},{"issue":"01","key":"ref35","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00005537-199901000-00010","article-title":"Myringoplasty in children: predictive factors of outcome","volume":"109","author":"F Denoyelle","year":"1999","journal-title":"Laryngoscope"},{"issue":"06","key":"ref36","first-page":"811","article-title":"Tympanosclerosis in the tympanic membrane: influence on outcome of myringoplasty","volume":"16","author":"E W Wielinga","year":"1995","journal-title":"Am J Otol"},{"issue":"09","key":"ref37","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1111\/j.1365-4632.2011.04940.x","article-title":"Wound healing in adult skin: aiming for perfect regeneration","volume":"50","author":"M C Heng","year":"2011","journal-title":"Int J Dermatol"},{"issue":"03","key":"ref38","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1152\/physrev.2003.83.3.835","article-title":"Regulation of wound healing by growth factors and cytokines","volume":"83","author":"S Werner","year":"2003","journal-title":"Physiol Rev"}],"container-title":["International Archives of Otorhinolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1791730.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:01:59Z","timestamp":1738368119000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1791730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":38,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2025,1,10]]},"published-print":{"date-parts":[[2025,1]]}},"alternative-id":["s00441791730"],"URL":"https:\/\/doi.org\/10.1055\/s-0044-1791730","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1809-9777","1809-4864"],"issn-type":[{"value":"1809-9777","type":"print"},{"value":"1809-4864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]}}}