{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T22:36:21Z","timestamp":1761345381212,"version":"build-2065373602"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>As the scope of endoscopic techniques continues to evolve in the treatment of advanced sinonasal malignancies, the primary challenge is the reconstruction of the resulting anterior skull base dural defect.<\/jats:p>\n                  <jats:p>This study aimed to assess the efficacy of vascularized pericranial flap reconstruction in addressing anterior skull base defects in sinonasal malignancies, particularly when alternative reconstructive methods, such as nasoseptal flaps, are not viable.<\/jats:p>\n                  <jats:p>We conducted a retrospective review of nine patients who underwent endoscopic resection of sinonasal malignancy followed by vascularized pericranial flap. Our analysis aimed to evaluate the surgical methods utilized, identify any complications that occurred, and assess the postoperative results of the patients.<\/jats:p>\n                  <jats:p>Excluding the singular instance of tension pneumocephalus that emerged during the immediate postoperative period, necessitating surgical intervention, our clinical experience was devoid of any complications, with a median follow-up duration of 18 months. It is worth noting that no cases of cerebrospinal fluid leaks or meningitis were reported. Moreover, the follow-up check endoscopy verified the successful integration of the flap and its efficacious coverage of the resection site.<\/jats:p>\n                  <jats:p>This study underscores the benefits of using vascularized pericranial flaps as an alternative solution for anterior skull base reconstruction in sinonasal malignancies. The availability of the pericranial flap in the local region, along with its robust blood supply, and the positive outcomes observed in this preliminary series collectively indicate its potential as an integral component of multi-layered reconstruction techniques for addressing anterior skull base defects.<\/jats:p>","DOI":"10.1055\/s-0044-1792079","type":"journal-article","created":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T20:20:22Z","timestamp":1730146822000},"page":"720-725","source":"Crossref","is-referenced-by-count":0,"title":["Anterior Skull Base Reconstruction Using a Vascularized Pericranial Flap: A Promising Alternative in Sinonasal Malignancies"],"prefix":"10.1055","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5792-6400","authenticated-orcid":false,"given":"Jeena","family":"Joseph","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun","family":"Govind","sequence":"additional","affiliation":[{"name":"Unit-1 (Head and Neck Skull Base Surgery), Department of ENT, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajan Sundaresan","family":"Vediappan","sequence":"additional","affiliation":[{"name":"Unit-1 (Head and Neck Skull Base Surgery), Department of ENT, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2069-1799","authenticated-orcid":false,"given":"Regi","family":"Thomas","sequence":"additional","affiliation":[{"name":"Unit-1 (Head and Neck Skull Base Surgery), Department of ENT, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gandham Edmond","family":"Jonathan","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishnaprabhu","family":"Raju","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2024,10,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.5152\/ejra.2019.230","article-title":"Endoscopic surgery for sinonasal cancer: Uluda\u011f experience","volume":"2","author":"H B Yavuz","year":"2019","journal-title":"Eur J Rhinol Allergy"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1001\/archotol.133.2.131","article-title":"Survival rates of sinonasal squamous cell carcinoma with the new AJCC staging system","volume":"133","author":"C H Lee","year":"2007","journal-title":"Arch Otolaryngol Head Neck 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flap","volume":"57","author":"N Yoshioka","year":"2005","journal-title":"Neurosurgery"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/alr.20051","article-title":"Outcome results of endoscopic vs craniofacial resection of sinonasal malignancies: a systematic review and pooled-data analysis","volume":"1","author":"T S Higgins","year":"2011","journal-title":"Int Forum Allergy Rhinol"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1097\/01.mlg.0000234933.37779.e4","article-title":"A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap","volume":"116","author":"G Hadad","year":"2006","journal-title":"Laryngoscope"},{"issue":"02","key":"ref9","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1002\/lary.22475","article-title":"Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence","volume":"122","author":"R J Harvey","year":"2012","journal-title":"Laryngoscope"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/lary.20022","article-title":"Minimally invasive endoscopic pericranial flap: a new method for endonasal skull base reconstruction","volume":"119","author":"A M Zanation","year":"2009","journal-title":"Laryngoscope"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1227\/01.NEU.0000365620.59677.FF","article-title":"Pericranial flap for endoscopic anterior skull-base reconstruction: clinical outcomes and radioanatomic analysis of preoperative planning","volume":"66","author":"M R Patel","year":"2010","journal-title":"Neurosurgery"},{"issue":"11","key":"ref12","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1002\/lary.26574","article-title":"Radio-anatomical analysis of the pericranial flap \u201cmoney box approach\u201d for ventral skull base reconstruction","volume":"127","author":"A Santamar\u00eda","year":"2017","journal-title":"Laryngoscope"},{"issue":"02","key":"ref13","first-page":"133","article-title":"Vascularized pericranial flap for endonasal anterior skull base reconstruction","volume":"83","author":"J Giurintano","year":"2021","journal-title":"J Neurol Surg B Skull Base"},{"issue":"11","key":"ref14","doi-asserted-by":"crossref","first-page":"2942","DOI":"10.1002\/lary.30921","article-title":"Pericranial flap-based multilayer reconstruction of endoscopic transcribriform craniectomy for sinonasal malignancies","volume":"133","author":"F Calvaruso","year":"2023","journal-title":"Laryngoscope"}],"container-title":["Journal of Neurological Surgery Part B: Skull 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