{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T10:39:53Z","timestamp":1782297593022,"version":"3.54.5"},"reference-count":12,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Homeopathic repertories are essential tools in remedy diagnosis, helping practitioners match patient symptoms with those produced by remedies. However, repertories often need to be revised due to omissions, misinterpretations, and incomplete representation of remedy symptoms. Despite their importance, the sensitivity of repertories \u2013 their ability to correctly identify remedies based on corresponding rubrics \u2013 has never been systematically estimated. Addressing this gap is crucial to ensuring repertories' accuracy, reliability and validity in homeopathic practice.<\/jats:p>\n                  <jats:p>We adopted the sensitivity formula used in medical diagnostics, where true positives indicate correct remedy identification and false negatives represent failures. This method was applied to Kent's repertory for Allium cepa using symptoms from Hering's Guiding Symptoms of our Materia Medica. We extracted the rubrics and identified the non-representing rubrics and omissions. We created a Python script that generated combinations of rubrics based on Allen's \u2018three-legged stool rule\u2019. We calculated the sensitivity as the ratio of true positives to total combinations.<\/jats:p>\n                  <jats:p>Of the 525 symptoms of Allium cepa, we extracted 364 rubrics from Kent's repertory, with 161 symptoms omitted. Among the extracted rubrics, 111 failed to represent Allium cepa. The Python script generated 23,979,550 combinations, of which 21,050,260 (87.78%) were false negatives, and 2,929,290 (12.2%) were true positives.<\/jats:p>\n                  <jats:p>The sensitivity of Kent's repertory for Allium cepa was estimated as 12.2%. The method can thus effectively estimate the sensitivity for given remedies in a homeopathic repertory. Applying this method to other remedies would enhance a repertory's diagnostic accuracy and could lead to the development of artificial intelligence-driven tools for repertorial analysis.<\/jats:p>","DOI":"10.1055\/s-0044-1801298","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T18:59:01Z","timestamp":1739213941000},"page":"249-253","source":"Crossref","is-referenced-by-count":3,"title":["A Novel Method for Estimating the Sensitivity of Homeopathic Repertories"],"prefix":"10.1055","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6150-0605","authenticated-orcid":false,"given":"Kurian","family":"Poruthukaren","sequence":"additional","affiliation":[{"name":"Department of Repertory, Yenepoya Homeopathic Medical College, AYUSH campus, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeenu","family":"Joseph","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine and Toxicology, Yenepoya Homeopathic Medical College, AYUSH campus, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Mathews","sequence":"additional","affiliation":[{"name":"Yenepoya Homeopathic Medical College, AYUSH Campus, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,2,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.homp.2008.11.004","article-title":"In search of the reliable repertory","volume":"98","author":"B Gadd","year":"2009","journal-title":"Homeopathy"},{"key":"ref2","first-page":"387","volume-title":"Evolution of Homoeopathic Repertories and Repertorisation","author":"J Kishore","year":"1998","edition":"1st ed."},{"key":"ref3","first-page":"159","volume-title":"Homoeopathic diagnosis: Hahnemann through B\u00f6nninghausen: an instruction manual with over fifty cases illustrating the application of the B\u00f6nninghausen Repertory therapeutic pocketbook method","author":"G Dimitriadis","year":"2004"},{"key":"ref4","first-page":"128","volume-title":"The Dynamics and Methodology of Homoeopathic Provings","author":"J Sherr","year":"1994","edition":"2nd ed."},{"key":"ref5","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.homp.2011.06.003","article-title":"No fear of ghosts in Lycopodium: a contribution to the discussion on repertory reliability","volume":"100","author":"U C Adler","year":"2011","journal-title":"Homeopathy"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1136\/ebnurs-2019-103225","article-title":"What are sensitivity and specificity?","volume":"23","author":"A Swift","year":"2020","journal-title":"Evid Based Nurs"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1001\/archinte.1997.00440220061008","article-title":"Upper-extremity deep vein thrombosis. Risk factors, diagnosis, and complications","volume":"157","author":"P Prandoni","year":"1997","journal-title":"Arch Intern Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.homp.2004.04.005","article-title":"Repertory and likelihood ratio: time for structural changes","volume":"93","author":"A LB Rutten","year":"2004","journal-title":"Homeopathy"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0007-0785(64)80013-2","article-title":"Acute prescribing","volume":"53","author":"K N Kasad","year":"1964","journal-title":"Br Homeopath J"},{"key":"ref10","volume-title":"Repertory of Homoeopathic Materia Medica by J T Kent. Corrected, Revised, and Improved","author":"R P Patel","edition":"Sixth American"},{"key":"ref11","volume-title":"The Guiding Symptoms of our Materia Medica","author":"C Hering","year":"1879"},{"key":"ref12","first-page":"868","volume-title":"Homeopathic drug pictures","author":"M L Tyler","year":"2001"}],"container-title":["Homeopathy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1801298.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T22:30:51Z","timestamp":1761258651000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1801298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,10]]},"references-count":12,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2025,10,23]]},"published-print":{"date-parts":[[2025,11]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1801298","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1475-4916","1476-4245"],"issn-type":[{"value":"1475-4916","type":"print"},{"value":"1476-4245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,10]]}}}