{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T04:44:07Z","timestamp":1741754647427,"version":"3.38.0"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000},"content-version":"vor","delay-in-days":99,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Avicenna J Med"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Variability in the prescription of antibiotics constitutes an area for improvement related to patient safety issues, including the risk of infection and health care efficiency based on evidence.<\/jats:p><jats:p>\n          Objectives\u2003The study aims to evaluate the effect of an intervention to reduce the duration of antibiotic treatment in complicated appendicitis.<\/jats:p><jats:p>\n          Methods\u2003A quality improvement program was implemented in the surgical department of The Cuban Hospital (Doha, Qatar). During a 3-month baseline period, data about antibiotic duration, consumption (daily defined doses), and cost (in Qatary Riyals) were identified, as well as during two plan-do-study-act (PDSA) intervention periods. Interventions include action focused on staff education, monitoring antibiotic use, feedback, and reminders during discharge planning.<\/jats:p><jats:p>\n          Results\u2003At baseline, 13 patients with complicated appendicitis were documented, while there were 41 and 15 patients during PDSA cycles 1 and 2, respectively. A 29.5% reduction in days of antibiotic treatment was observed during the PDSA cycle 2 in comparison with the baseline. Accordingly, a reduction of 38.7% in the consumption of antibiotics and a reduction of 24.6% in cost were observed, with no adverse outcomes for patients during the 30-day follow-up period.<\/jats:p><jats:p>\n          Conclusion\u2003The intervention resulted in an improvement in antibiotic use with satisfactory patient outcomes and an additional effect on the efficiency of health care and the prevention of microbial resistance and other adverse effects.<\/jats:p>","DOI":"10.1055\/s-0044-1801350","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T23:58:31Z","timestamp":1736380711000},"page":"210-215","source":"Crossref","is-referenced-by-count":0,"title":["Reduction of Antibiotic Prescription in Complicated Appendicitis through Behavioral Change Measures"],"prefix":"10.1055","volume":"14","author":[{"given":"Alberto A.","family":"Artiles Garcia","sequence":"additional","affiliation":[{"name":"Department of Surgical, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7279-0062","authenticated-orcid":false,"given":"Humberto","family":"Guanche Garcell","sequence":"additional","affiliation":[{"name":"Department of Infection Control, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel J.","family":"Pinto Echevarr\u00eda","sequence":"additional","affiliation":[{"name":"Department of Surgical, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A.","family":"Sanchez Portela","sequence":"additional","affiliation":[{"name":"Department of Surgical, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos M.","family":"Sanchez Rivas","sequence":"additional","affiliation":[{"name":"Department of Surgical, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlon","family":"Arias Medina","sequence":"additional","affiliation":[{"name":"Department of Surgical, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niuvis","family":"Seoane Perez","sequence":"additional","affiliation":[{"name":"Dep\u00e1rtment of Pharmacy, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osiris I.","family":"Escobar More","sequence":"additional","affiliation":[{"name":"Department of Surgical, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania M.","family":"Fernandez Hernandez","sequence":"additional","affiliation":[{"name":"Dep\u00e1rtment of Medical Administration, The Cuban Hospital, Dukhan, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,1,8]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","author":"Antimicrobial Resistance Collaborators","year":"2022","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"106103","DOI":"10.1016\/j.ejps.2021.106103","article-title":"Antimicrobial resistance: prevalence, economic burden, mechanisms of resistance and strategies to overcome","volume":"170","author":"T Pulingam","year":"2022","journal-title":"Eur J Pharm Sci"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1111\/ans.16615","article-title":"Duration of post-operative antibiotic treatment in acute complicated appendicitis: systematic review and meta-analysis","volume":"91","author":"D M Ramson","year":"2021","journal-title":"ANZ J Surg"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.surg.2019.08.007","article-title":"Perforated appendicitis: short duration antibiotics are noninferior to traditional long duration antibiotics","volume":"167","author":"A David","year":"2020","journal-title":"Surgery"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s13017-020-00306-3","article-title":"Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines","volume":"15","author":"S Di Saverio","year":"2020","journal-title":"World J Emerg Surg"},{"issue":"04","key":"ref6","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.jhqr.2024.03.003","article-title":"A quality improvement intervention on surgical prophylaxis impact in antibiotic consumption and cost in selected surgical procedures","volume":"39","author":"H Guanche Garcell","year":"2024","journal-title":"J Healthc Qual Res"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"8933","DOI":"10.1007\/s00464-023-10456-5","article-title":"Diagnosis and treatment of appendicitis: systematic review and meta-analysis","volume":"37","author":"R Lamm","year":"2023","journal-title":"Surg Endosc"},{"issue":"01","key":"ref8","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s00423-024-03367-z","article-title":"Antibiotic treatment after appendectomy for acute complicated appendicitis to prevent intrabdominal abscess and wound infections","volume":"409","author":"B LB Laverde","year":"2024","journal-title":"Langenbecks Arch Surg"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.jss.2019.09.054","article-title":"Complicated appendicitis: are extended antibiotics necessary? A post hoc analysis of the EAST appendicitis \u201cMUSTANG\u201d study","volume":"247","author":"S Bou Zein Eddine","year":"2020","journal-title":"J Surg Res"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jss.2020.12.059","article-title":"Eliminating use of home oral antibiotics in pediatric complicated appendicitis","volume":"263","author":"B Ketha","year":"2021","journal-title":"J Surg Res"},{"volume-title":"The WHO AWaRe (Access, Watch, Reserve) antibiotic book. Web Annex. Infographics","year":"2023","key":"ref11"},{"issue":"01","key":"ref12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1089\/sur.2021.144","article-title":"Improving antibiotic stewardship in acute appendicitis through risk-based empiric treatment selection","volume":"23","author":"W Bauerle","year":"2022","journal-title":"Surg Infect (Larchmt)"},{"issue":"02","key":"ref13","first-page":"CD003543","article-title":"Interventions to improve antibiotic prescribing practices for hospital inpatients","volume":"2","author":"P Davey","year":"2017","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Avicenna Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0044-1801350.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:20:35Z","timestamp":1741738835000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0044-1801350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":13,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2025,3,11]]},"published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0044-1801350","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2231-0770","2249-4464"],"issn-type":[{"type":"print","value":"2231-0770"},{"type":"electronic","value":"2249-4464"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}