{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T19:24:48Z","timestamp":1770060288719,"version":"3.49.0"},"reference-count":69,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Semin intervent Radiol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The vascular system is an intricate system that develops during early periods of embryogenesis. Through a complex signaling pathway of vasculogenesis and angiogenesis, embryonic vessels grow and coalesce, which allows nutrient and waste management. Dysfunction in these endothelial cells gives rise to vascular variants. Throughout gestational development, vascular variants can form in different organ systems such as the thoracic cavity, hepatic, renal, and lower pelvis. It is clinically very important for physicians to recognize these variants, as these variants can predispose to certain illnesses and treatment of patients surgically. This article discusses the embryology and vascular variants of the arterial system with a focus on the thoracic cavity, hepatic, renal, and pelvic variations to help aid in minimizing technical complications during procedures.<\/jats:p>","DOI":"10.1055\/s-0045-1802308","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T23:43:21Z","timestamp":1740095001000},"page":"219-228","source":"Crossref","is-referenced-by-count":1,"title":["Embryology of the Vascular System: Implications for Variants"],"prefix":"10.1055","volume":"42","author":[{"given":"Ronak K.","family":"Patel","sequence":"additional","affiliation":[{"name":"University of Kentucky College of Medicine, William R. Willard Medical Education Building, Lexington, Kentucky"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curtis L.","family":"Simmons","sequence":"additional","affiliation":[{"name":"Department of Radiology, Phoenix Children's Hospital, Phoenix, Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"Ozen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Phoenix, Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,2,20]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"2269","DOI":"10.2741\/e541","article-title":"Life is a pattern: vascular assembly within the embryo","volume":"4","author":"J Heinke","year":"2012","journal-title":"Front Biosci (Elite Ed)"},{"key":"ref2","first-page":"344","volume-title":"Chapter nine - vascular development, remodeling and maturation","author":"J Furtado","year":"2024"},{"issue":"05","key":"ref3","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1096\/fasebj.11.5.9141503","article-title":"Vascular development: cellular and molecular regulation","volume":"11","author":"L Beck Jr","year":"1997","journal-title":"FASEB J"},{"issue":"04","key":"ref4","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1161\/ATVBAHA.114.304768","article-title":"Etv2 and fli1b function together as key regulators of vasculogenesis and angiogenesis","volume":"35","author":"M P Craig","year":"2015","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"03","key":"ref5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/wdev.91","article-title":"Understanding vascular development","volume":"2","author":"R S Udan","year":"2013","journal-title":"Wiley Interdiscip Rev Dev Biol"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1161\/ATVBAHA.118.310223","article-title":"Vascular development","volume":"38","author":"M W Majesky","year":"2018","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/nm0603-685","article-title":"Molecular regulation of vessel maturation","volume":"9","author":"R K Jain","year":"2003","journal-title":"Nat Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.matbio.2017.07.004","article-title":"Marfan syndrome; a connective tissue disease at the crossroads of mechanotransduction, TGF\u03b2 signaling and cell stemness","volume":"71-72","author":"F Ramirez","year":"2018","journal-title":"Matrix Biol"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1055\/s-0037-1604296","article-title":"Vascular anomalies caused by abnormal signaling within endothelial cells: targets for novel therapies","volume":"34","author":"H L Nguyen","year":"2017","journal-title":"Semin Intervent Radiol"},{"issue":"04","key":"ref10","first-page":"e14451","article-title":"Literature review of anatomical variations: clinical significance, identification approach, and teaching strategies","volume":"13","author":"A Alraddadi","year":"2021","journal-title":"Cureus"},{"key":"ref11","first-page":"100107","article-title":"Analysis of surgical errors associated with anatomical variations clinically relevant in general surgery. 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