{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T14:39:45Z","timestamp":1778164785707,"version":"3.51.4"},"reference-count":18,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Spinal extradural angiolipomas (SEALs) are rare, benign neoplasms composed of mature adipocytes and vascular elements. They are often noninfiltrating and located in the posterior aspect of the spinal canal at the level of thoracic\/dorsal vertebrae. Back pain, progressive paraparesis, and sensory disturbance in lower limbs are the typical symptoms. Here, we discuss two cases of SEALs presenting with subacute paraparesis. The magnetic resonance imaging of one patient was reported to be suggestive of spinal metastasis\/plasmacytoma\/sarcoma, while the other was reported as a spinal extradural hematoma. After laminectomy, both lesions were recognized as encapsulated extradural tumors and en-bloc resection was done. Postoperatively, the neurological deficits improved and there was no recurrence on 2-year follow-up. Histopathology characterized both of them to be extradural angiolipomas. Current experience and literature support curative surgical resection as the gold standard. The prognosis is excellent in most cases, even if total resection is not feasible. It is due to the slow-growing nature of the tumor and absence of malignant transformation.<\/jats:p>","DOI":"10.1055\/s-0045-1802625","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T20:20:53Z","timestamp":1742847653000},"page":"387-390","source":"Crossref","is-referenced-by-count":2,"title":["Spinal Extradural Angiolipoma: A Report of Two Cases and Review of Literature"],"prefix":"10.1055","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8811-2931","authenticated-orcid":false,"given":"Sathish Kumar","family":"Thellakanthiah Ekambaram","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arul","family":"Muthukumaraswamy","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Madras Institute of Orthopaedics and Traumatology, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vigneshwar Kumbakonam","family":"Sivaraman","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7171-5671","authenticated-orcid":false,"given":"Gokulesh Devannagoundanur","family":"Gurumurthy","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandini","family":"Vijayakumar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dr. Kamakshi Memorial Hospital, Chennai, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"issue":"12","key":"ref1","first-page":"e12380","article-title":"Lumbar extradural angiolipoma: clinical presentation and management","volume":"12","author":"T Ikpeze","year":"2020","journal-title":"Cureus"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00586-013-3073-1","article-title":"Spinal angiolipoma: etiology, imaging findings, classification, treatment, and prognosis","volume":"23","author":"Y Si","year":"2014","journal-title":"Eur Spine J"},{"issue":"01","key":"ref3","doi-asserted-by":"crossref","first-page":"17473","DOI":"10.1038\/s41598-024-67584-8","article-title":"Demographic and clinical data of patients with spinal epidural angiolipomas","volume":"14","author":"T Lu","year":"2024","journal-title":"Sci Rep"},{"issue":"19","key":"ref4","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1097\/00007632-199710010-00022","article-title":"Subacute paraparesis induced by venous thrombosis of a spinal angiolipoma: a case report","volume":"22","author":"J A Boockvar","year":"1997","journal-title":"Spine"},{"issue":"06","key":"ref5","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/00007632-199206000-00013","article-title":"Spinal extradural angiolipoma. 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A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma","volume":"34","author":"J J Lin","year":"1974","journal-title":"Cancer"},{"issue":"08","key":"ref13","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0046-8177(81)80176-1","article-title":"Angiolipomas: an ultrastructural and clinicopathological study","volume":"12","author":"A Y Dixon","year":"1981","journal-title":"Hum Pathol"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s13244-015-0432-y","article-title":"Haemangioma, an uncommon cause of an extradural or intradural extramedullary mass: case series with radiological pathological correlation","volume":"7","author":"S H McEvoy","year":"2016","journal-title":"Insights Imaging"},{"issue":"13","key":"ref15","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1097\/00007632-200007010-00021","article-title":"Liposarcoma in the epidural space","volume":"25","author":"S Turanli","year":"2000","journal-title":"Spine"},{"issue":"05","key":"ref16","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.jbspin.2008.02.003","article-title":"Angiomyolipoma occurred at the cervical spine","volume":"75","author":"N Jia","year":"2008","journal-title":"Joint Bone Spine"},{"issue":"03","key":"ref17","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1007\/s00586-008-0858-8","article-title":"Spinal extradural angiolipoma: report of two cases and review of the literature","volume":"18","author":"M Gelabert-Gonz\u00e1lez","year":"2009","journal-title":"Eur Spine J"},{"issue":"10","key":"ref18","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.jocn.2007.07.084","article-title":"Infiltrating spinal angiolipoma","volume":"15","author":"H L Yen","year":"2008","journal-title":"J Clin Neurosci"}],"container-title":["Asian Journal of Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0045-1802625.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:50:45Z","timestamp":1756360245000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0045-1802625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,24]]},"references-count":18,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2025,6,4]]},"published-print":{"date-parts":[[2025,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0045-1802625","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1793-5482","2248-9614"],"issn-type":[{"value":"1793-5482","type":"print"},{"value":"2248-9614","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,24]]}}}