{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T17:16:04Z","timestamp":1788801364468,"version":"build-2803163510"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T00:00:00Z","timestamp":1745798400000},"content-version":"vor","delay-in-days":86,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ortop (Sao Paulo)"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Resumo<\/jats:title><jats:p>\n          Objetivo\u2003O tratamento cir\u00fargico de tumores \u00f3sseos \u00e9 agressivo por natureza e frequentemente seguido por complica\u00e7\u00f5es relacionadas com a ferida (CRFs). Para minimizar esses eventos, diferentes estrat\u00e9gias foram empregadas e o penso de press\u00e3o negativa (closed-incision negative-pressure wound therapy, ciNPWT, em ingl\u00eas) emergiu como poss\u00edvel adjuvante. Neste estudo, pretendemos avaliar o impacto dessa t\u00e9cnica na minimiza\u00e7\u00e3o de CRFs em pacientes com tumores de f\u00eamur proximal e distal tratados com megapr\u00f3teses.<\/jats:p><jats:p>\n          M\u00e9todos\u2003Este estudo retrospectivo observacional incluiu 41 participantes diagnosticados com tumores de f\u00eamur proximal ou distal tratados com ressec\u00e7\u00e3o alargada e reconstru\u00e7\u00e3o com megapr\u00f3tese. Os pacientes foram divididos em dois grupos com base no penso cir\u00fargico p\u00f3s-operat\u00f3rio aplicado: grupo de encerramento assistido por v\u00e1cuo (vacuum-assisted closure, VAC, em ingl\u00eas), onde foi aplicado ciNPWT; e grupo n\u00e3o-VAC, que recebeu pensos convencionais. Dados sobre CRFs p\u00f3s-operat\u00f3rias e outras poss\u00edveis vari\u00e1veis de interesse foram registados. A an\u00e1lise estat\u00edstica foi realizada recorrendo ao programa IBM SPSS Statistics, vers\u00e3o 24.0.<\/jats:p><jats:p>\n          Resultados Foram 20 pacientes inclu\u00eddos no grupo VAC e 21 no grupo n\u00e3o-VAC. A maioria dos pacientes n\u00e3o apresentou complica\u00e7\u00f5es e n\u00e3o houve diferen\u00e7as entre os grupos em termos de CRFs, incluindo infec\u00e7\u00e3o. No entanto, deisc\u00eancia da ferida e extravasamento persistente de fluido tiveram correla\u00e7\u00e3o positiva com o diagn\u00f3stico de infec\u00e7\u00e3o que, juntos, apresentaram correla\u00e7\u00e3o com a necessidade de revis\u00e3o cir\u00fargica.<\/jats:p><jats:p>\n          Conclus\u00e3o\u2003Apesar da aus\u00eancia de signific\u00e2ncia estat\u00edstica, a ciNPWT parece ajudar a minimizar a deisc\u00eancia da ferida, o extravasamento persistente da ferida e as infec\u00e7\u00f5es da ferida operat\u00f3ria em pacientes com tumores \u00f3sseos do f\u00eamur proximal e distal tratados com megapr\u00f3tese. Al\u00e9m disso, a deisc\u00eancia da ferida e o extravasamento persistente da ferida foram bem correlacionados com a infec\u00e7\u00e3o de ferida operat\u00f3ria, e os tr\u00eas par\u00e2metros est\u00e3o correlacionados com a necessidade de revis\u00e3o cir\u00fargica.<\/jats:p>","DOI":"10.1055\/s-0045-1802965","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T23:07:57Z","timestamp":1745881677000},"page":"001-010","source":"Crossref","is-referenced-by-count":1,"title":["Terapia de press\u00e3o negativa com a ferida encerrada em reconstru\u00e7\u00f5es do f\u00e9mur proximal e distal com megapr\u00f3teses ap\u00f3s ressec\u00e7\u00f5es de tumores \u00f3sseos"],"prefix":"10.1055","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0132-7526","authenticated-orcid":false,"given":"Joaquim","family":"Soares do Brito","sequence":"additional","affiliation":[{"name":"Departamento de Ortopedia e Trauma, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria,Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0728-6614","authenticated-orcid":false,"given":"Rodrigo","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Grupo de Oncologia Ortop\u00e9dica, Instituto Nacional de Traumatologia e Ortopedia, Rio de Janeiro, Brasil"},{"name":"Grupo de Oncologia Ortop\u00e9dica, Hospital Universit\u00e1rio Gaffre Guinle, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1209-4425","authenticated-orcid":false,"given":"Rodrigo","family":"Goes","sequence":"additional","affiliation":[{"name":"Departamento de Ortopedia e Trauma, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria,Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3585-9301","authenticated-orcid":false,"given":"Andr\u00e9","family":"Spranger","sequence":"additional","affiliation":[{"name":"Departamento de Ortopedia e Trauma, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria,Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4650-3864","authenticated-orcid":false,"given":"Paulo","family":"Almeida","sequence":"additional","affiliation":[{"name":"Departamento de Ortopedia e Trauma, Hospital de Santa Maria, Unidade Local de Sa\u00fade Santa Maria,Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1894-7134","authenticated-orcid":false,"given":"Jos\u00e9","family":"Portela","sequence":"additional","affiliation":[{"name":"Departamento de Ortopedia e Trauma, Hospital de Santa Maria, Unidade Local de Sa\u00fade 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