{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:20:03Z","timestamp":1758759603650,"version":"3.44.0"},"reference-count":41,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sleep Sci"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To verify the feasibility of high-resolution oximeter plus actigraphy combined with a cloud-based algorithm for the detection of obstructive sleep apnea (OSA) in children with craniofacial anomalies.<\/jats:p><jats:p>In the present prospective, cross-sectional study, we evaluated children previously submitted to primary surgical palate repair with a genetically confirmed diagnosis of Treacher Collins syndrome (TCS), non-syndromic Robin sequence (NSRS), or non-syndromic cleft palate (NSCP). The children underwent a clinical evaluation, had their anthropometric measures taken, and were submitted to OSA detection using high-resolution oximeter plus actigraphy combined with a cloud-based algorithm (Biologix Sleep Test, Biologix Sistemas S.A., S\u00e3o Paulo, SP, Brazil).<\/jats:p><jats:p>In total, 64 children (TCS: n\u2009=\u200916; NSRS: n\u2009=\u200929; NSCP: n\u2009=\u200919) were included in the final analysis (mean age: 10\u2009\u00b1\u20092 years; 64% of female patients). The Biologix Sleep Test showed that 59 patients (92%) presented OSA according to the oxygen desaturation index (ODI): 36 (56%) were diagnosed with mild OSA, 19 (30%), with moderate OSA, and 4 (6%), with severe OSA. The high-resolution oximeter recording showed excellent signal quality in 94.53\u2009\u00b1\u20095.29% of the exams, with a success rate of exams on the first night of 90%. No significant difference was found in terms of ODI among the subgroups (p\u2009&gt;\u20090.05). A significant relationship was observed between increased ODI with greater hypoxic burden and lower estimated sleep efficiency. The multiple linear regression analysis demonstrated a significant association between changes in total ODI with lower estimated sleep efficiency and sleep ODI.<\/jats:p><jats:p>High-resolution oximeter plus actigraphy combined with a cloud-based algorithm demonstrated adequate feasibility and applicability for OSA detection in children with craniofacial anomalies.<\/jats:p>","DOI":"10.1055\/s-0045-1802967","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T23:00:22Z","timestamp":1743116422000},"page":"e253-e261","source":"Crossref","is-referenced-by-count":1,"title":["Feasibility of High-Resolution Oximeter Plus Actigraphy Combined with a Cloud-Based Algorithm for the Detection of Obstructive Sleep Apnea in Children with Craniofacial Anomalies"],"prefix":"10.1055","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7642-0146","authenticated-orcid":false,"given":"Sergio Henrique Kiemle","family":"Trindade","sequence":"additional","affiliation":[{"name":"Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, SP, Brazil"},{"name":"Faculdade de Medicina de Bauru, Universidade de S\u00e3o Paulo (FMBRU-USP), Bauru, SP, Brazil"},{"name":"Department of Otorhinolaryngology, Hospital de Reabilita\u00e7\u00e3o de Anomalias Craniofaciais (HRAC), Universidade de S\u00e3o Paulo (USP), Bauru, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9429-8298","authenticated-orcid":false,"given":"F\u00e1bio Luiz","family":"Banhara","sequence":"additional","affiliation":[{"name":"Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leide Vilma","family":"Fid\u00e9lis da Silva","sequence":"additional","affiliation":[{"name":"Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9983-8812","authenticated-orcid":false,"given":"Sara Quaglia de Campos","family":"Giamp\u00e1","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Research on Sleep (LIM\/63), Division of Pulmonology, Department of Cardiopulmonology, Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas, Faculty of Medicine, Universidade de S\u00e3o Paulo (HCFMUSP), S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lais Mota Furtado","family":"Sena","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Hospital de Reabilita\u00e7\u00e3o de Anomalias Craniofaciais (HRAC), Universidade de S\u00e3o Paulo (USP), Bauru, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8582-0072","authenticated-orcid":false,"given":"Ivy Kiemle","family":"Trindade-Suedam","sequence":"additional","affiliation":[{"name":"Sleep Studies Unit, Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, Bauru, SP, Brazil"},{"name":"Department of Biological Sciences, Bauru School of Dentistry, Universidade de S\u00e3o Paulo (USP), Bauru SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"issue":"03","key":"ref1","doi-asserted-by":"crossref","first-page":"e714","DOI":"10.1542\/peds.2012-1672","article-title":"Diagnosis and management of childhood obstructive sleep apnea syndrome","volume":"130","author":"C L 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