{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T04:24:45Z","timestamp":1742963085040,"version":"3.40.3"},"reference-count":27,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":46,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003The data on predictors of poor outcomes for stroke patients in middle-income countries are lacking.<\/jats:p><jats:p>\n          Objective\u2003To identify in the acute phase after a first-ever stroke (FES) predictors of a poor outcome within 3 months and 1 year in a population-based study in the town of Mat\u00e3o, state of S\u00e3o Paulo, Brazil.<\/jats:p><jats:p>\n          Methods\u2003We prospectively investigated the characteristics of patients with FES in Mat\u00e3o, from a prospective study, in a population-based stroke registry, from 2015 to 2020. Poor outcome was defined as a modified Rankin scale (mRS) score of 3 to 6, assessed at 3 months and 1 year of follow-up. The association between predictors and poor outcome was analyzed by logistic regression analysis.<\/jats:p><jats:p>\n          Results\u2003Of the 783 patients, the final sample consisted of 378 subjects for analysis. The mean age was 69.2(\u00b1\u200914.3) years, and 43.1% of patients were female. At 3 months and 1 year after a FES, 50.4% and 47.1% of stroke patients were classified as poor prognosis, respectively. Older age, female gender, hemiplegia, aphasia, subarachnoid hemorrhage, and comorbidities present in the acute phase were the predictors associated with a poor outcome.<\/jats:p><jats:p>\n          Conclusion\u2003Non-modified and potentially modified predictors increase the risk of a poor FES prognosis in a population-based study from a middle-income country. Interventions focusing on these target populations and improving access to prevention and stroke management in the acute phase are necessary.<\/jats:p>","DOI":"10.1055\/s-0045-1804924","type":"journal-article","created":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T23:58:52Z","timestamp":1742428732000},"page":"001-007","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of poor outcome in the acute phase after a first-ever stroke in a population-based study in Mat\u00e3o, Brazil"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3969-6629","authenticated-orcid":false,"given":"Cesar","family":"Minelli","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina de Ribeir\u00e3o Preto, Departamento de Neuroci\u00eancias e Ci\u00eancias do Comportamento, Ribeir\u00e3o Preto SP, Brazil."},{"name":"Hospital Carlos Fernando Malzoni, Departamento de Neurologia, Mat\u00e3o SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0505-8569","authenticated-orcid":false,"given":"Esther Maria Langhi","family":"Chiozzini","sequence":"additional","affiliation":[{"name":"Hospital Carlos Fernando Malzoni, Departamento de Neurologia, Mat\u00e3o SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4388-2767","authenticated-orcid":false,"given":"Liliana Tiene","family":"Ujikawa","sequence":"additional","affiliation":[{"name":"Hospital Carlos Fernando Malzoni, Departamento de Neurologia, Mat\u00e3o SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3183-7546","authenticated-orcid":false,"given":"Geraldo Cassio dos","family":"Reis","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina de Ribeir\u00e3o Preto, Departamento de Neuroci\u00eancias e Ci\u00eancias do Comportamento, Ribeir\u00e3o Preto SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0310-6033","authenticated-orcid":false,"given":"Millene Rodrigues","family":"Camilo","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina de Ribeir\u00e3o Preto, Departamento de Neuroci\u00eancias e Ci\u00eancias do Comportamento, Ribeir\u00e3o Preto SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0317-843X","authenticated-orcid":false,"given":"Octavio Marques","family":"Pontes-Neto","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina de Ribeir\u00e3o Preto, Departamento de Neuroci\u00eancias e Ci\u00eancias do Comportamento, Ribeir\u00e3o Preto SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1161\/01.STR.0000082382.42061.EE","article-title":"Ten-year survival after first-ever stroke in the perth community stroke study","volume":"34","author":"K Hardie","year":"2003","journal-title":"Stroke"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1161\/01.STR.0000047852.05842.3C","article-title":"Poor outcome after first-ever stroke: predictors for death, dependency, and recurrent stroke within the first year","volume":"34","author":"P Appelros","year":"2003","journal-title":"Stroke"},{"issue":"10","key":"ref3","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1161\/STROKEAHA.113.001584","article-title":"Population-based study of disability and institutionalization after transient ischemic attack and stroke: 10-year results of the Oxford Vascular Study","volume":"44","author":"R Luengo-Fernandez","year":"2013","journal-title":"Stroke"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"e340","DOI":"10.1016\/S2214-109X(20)30470-8","article-title":"Incidence, risk factors, prognosis, and health-related quality of life after stroke in a low-resource community in Chile (\u00d1ANDU): a prospective population-based study","volume":"9","author":"P M Lavados","year":"2021","journal-title":"Lancet Glob Health"},{"issue":"07","key":"ref5","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1177\/1747493018763906","article-title":"Five-year survival, disability, and recurrence after first-ever stroke in a middle-income country: A population-based study in Joinvile, Brazil","volume":"13","author":"N L Cabral","year":"2018","journal-title":"Int J Stroke"},{"issue":"01","key":"ref6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000503005","article-title":"Trends 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