{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T00:30:18Z","timestamp":1761438618471,"version":"3.40.5"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nucl Med"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Diffuse malignant peritoneal mesothelioma (DMPM) is a rare and aggressive subtype of epithelioid mesothelioma that arises from the lining of the abdominal cavity. While the applications of traditional fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography\/computed tomography (PET\/CT) in diagnosis and staging of DMPM are well-established, the utility of gallium-68 fibroblast activating protein inhibitor (68Ga-FAPI) PET\/CT in detecting disease recurrence remains an area that requires further research and validation, with limited literature. Implementing FAPI PET\/CT for these cases may provide superior lesion detectability and higher reporter confidence, prompting the need for further studies to investigate the potential future role of FAPI theranostics in guiding treatment decisions for DMPM. This case report describes a 49-year-old male patient diagnosed with DMPM, who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy but developed recurrent disease that was better visualized on 68Ga-FAPI PET\/CT compared with 18F-FDG PET\/CT.<\/jats:p>","DOI":"10.1055\/s-0045-1805043","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:16:41Z","timestamp":1741825001000},"page":"185-188","source":"Crossref","is-referenced-by-count":1,"title":["Enhanced Detection of Recurrent Diffuse Malignant Peritoneal Mesothelioma Using 68Ga-FAPI PET\/CT Compared to 18F-FDG PET\/CT: A Case Report"],"prefix":"10.1055","volume":"24","author":[{"given":"Marwah","family":"Abdulrahman","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, King Hussein Cancer Center (KHCC), Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ula","family":"Al-Rasheed","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, King Hussein Cancer Center (KHCC), Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Dabous","sequence":"additional","affiliation":[{"name":"Department of Transplant and Oncosurgery, King Hussein Cancer Center (KHCC), Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0978-4716","authenticated-orcid":false,"given":"Akram","family":"Al-Ibraheem","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, King Hussein Cancer Center (KHCC), Amman, Jordan"},{"name":"Department of Radiology and Nuclear Medicine, School of Medicine, the University of Jordan, Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"ref2","doi-asserted-by":"crossref","first-page":"1611577","DOI":"10.3389\/pore.2023.1611577","article-title":"Clinical and pathological observation of conversion therapy for malignant peritoneal mesothelioma: a case report and literature review","volume":"29","author":"M Deng","year":"2024","journal-title":"Pathol Oncol Res"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1015884","DOI":"10.3389\/fsurg.2022.1015884","article-title":"Diffuse malignant peritoneal mesothelioma: a review","volume":"9","author":"L Sun","year":"2023","journal-title":"Front Surg"},{"issue":"01","key":"ref4","first-page":"1","article-title":"Peritoneal deposits: PET\/CT the keen observer","volume":"54","author":"N NAA Mikawy","year":"2023","journal-title":"Egypt J Radiol Nucl Med"},{"issue":"1081","key":"ref5","doi-asserted-by":"crossref","first-page":"20170519","DOI":"10.1259\/bjr.20170519","article-title":"Diagnostic accuracy of 18F-FDG PET\/CT for detection of peritoneal carcinomatosis; a systematic review and meta-analysis","volume":"91","author":"S J Kim","year":"2018","journal-title":"Br J Radiol"},{"issue":"07","key":"ref6","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1097\/MNM.0000000000001702","article-title":"Comparison of the role of 18 F-fluorodeoxyglucose PET\/computed tomography and 68 Ga-labeled FAP inhibitor-04 PET\/CT in patients with malignant mesothelioma","volume":"44","author":"Y G\u00fczel","year":"2023","journal-title":"Nucl Med Commun"},{"issue":"13","key":"ref7","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1007\/s00259-021-05307-1","article-title":"Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET\/CT in cancer patients","volume":"48","author":"F L Giesel","year":"2021","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2480493","DOI":"10.1155\/2023\/2480493","article-title":"Fibroblast activation protein expression in sarcomas","volume":"2023","author":"J N Crane","year":"2023","journal-title":"Sarcoma"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.cpet.2023.03.001","article-title":"Fibroblast activation protein inhibitor (FAPI)-PET imaging in sarcoma","volume":"18","author":"L Kessler","year":"2023","journal-title":"PET Clin"},{"issue":"02","key":"ref10","doi-asserted-by":"crossref","first-page":"499","DOI":"10.3390\/cancers12020499","article-title":"Mesothelial-to-mesenchymal transition contributes to the generation of carcinoma-associated fibroblasts in locally advanced primary colorectal carcinomas","volume":"12","author":"C H Gordillo","year":"2020","journal-title":"Cancers (Basel)"},{"issue":"02","key":"ref11","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2214\/AJR.20.24302","article-title":"Will FAPI PET\/CT replace FDG PET\/CT in the next decade? Point-an important diagnostic, phenotypic, and biomarker role","volume":"216","author":"J Calais","year":"2021","journal-title":"AJR Am J Roentgenol"},{"issue":"02","key":"ref12","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1097\/RLU.0000000000003858","article-title":"68Ga-FAPI-04 PET\/CT versus 18F-FDG PET\/CT in malignant peritoneal mesothelioma","volume":"47","author":"C G\u00fcndo\u011fan","year":"2022","journal-title":"Clin Nucl Med"},{"issue":"04","key":"ref13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/RLU.0000000000004575","article-title":"Malignant peritoneal mesothelioma with butterfly-shaped muscle metastasis: 68Ga-FAPI PET\/CT versus 18F-FDG PET\/CT","volume":"48","author":"J Li","year":"2023","journal-title":"Clin Nucl Med"},{"issue":"02","key":"ref14","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1055\/s-0044-1787886","article-title":"Fibroblast activation protein inhibitor theranostics: a huge opportunity with its fair share of oncological pitfalls","volume":"23","author":"A Al-Ibraheem","year":"2024","journal-title":"World J Nucl Med"},{"issue":"03","key":"ref15","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1053\/j.semnuclmed.2024.01.001","article-title":"Fibroblast activation protein inhibitor (FAPI) PET imaging in sarcomas: a new frontier in nuclear medicine","volume":"54","author":"F Giammarile","year":"2024","journal-title":"Semin Nucl Med"}],"container-title":["World Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0045-1805043.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T22:38:16Z","timestamp":1746571096000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0045-1805043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,12]]},"references-count":14,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2025,5,6]]},"published-print":{"date-parts":[[2025,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0045-1805043","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1450-1147","1607-3312"],"issn-type":[{"type":"print","value":"1450-1147"},{"type":"electronic","value":"1607-3312"}],"subject":[],"published":{"date-parts":[[2025,3,12]]}}}