{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T23:10:03Z","timestamp":1745795403786,"version":"3.40.4"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T00:00:00Z","timestamp":1745712000000},"content-version":"vor","delay-in-days":57,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Individuals with Parkinson's disease (PD) often experience gait disturbances, and one of the most disabling is freezing of gait (FOG), which is characterized by the inability to initiate or continue walking. To identify its impact on the mobility of PD patients, it is necessary to objectively assess mobility and conduct systematic gait evaluations.<\/jats:p><jats:p>\n          Objective\u2003To evaluate mobility and gait parameters in individuals with PD with and without FOG.<\/jats:p><jats:p>\n          Methods\u2003The present cross-sectional study included a group of individuals with PD, divided into those with and without FOG, and a healthy control group. The Timed Up and Go (TUG) test was used to evaluate gait and mobility of the participants. Activities of daily living and motor performance in PD patients were assessed through parts II and III of the Movement Disorder Society Unified Parkinson Disease Rating Scale (MDS-UPDRS), while FOG was assessed through the New Freezing of Gait Questionnaire (NFOG-Q).<\/jats:p><jats:p>\n          Results\u2003A significant difference between the case and control groups was observed in the mean time it took to perform the TUG test, regardless of FOG, during the off-medication state. Unlike the group without FOG, there was a difference in the time it took to perform the tests between medication states in the group with FOG. Additionally, a correlation was found between TUG time and MDS-UPDRS scores in the FOG group.<\/jats:p><jats:p>\n          Conclusion\u2003Mobility in PD is influenced by medication effect and the presence of FOG. The results highlight the importance of objective and systematic gait evaluations to identify mobility problems, develop effective rehabilitation strategies, and optimize pharmacological treatments, especially for individuals with FOG.<\/jats:p>","DOI":"10.1055\/s-0045-1806821","type":"journal-article","created":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T22:51:16Z","timestamp":1745794276000},"page":"001-006","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of mobility parameters in individuals with Parkinson's disease with and without freezing of gait"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3026-6267","authenticated-orcid":false,"given":"Cristiane Ramos de","family":"Morais","sequence":"additional","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ndia, Faculdade de Engenharia El\u00e9trica, N\u00facleo de Inova\u00e7\u00e3o e Avalia\u00e7\u00e3o Tecnol\u00f3gica em Sa\u00fade, Uberl\u00e2ndia MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4235-4141","authenticated-orcid":false,"given":"Tamine T. C.","family":"Capato","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Departamento de Neurologia, S\u00e3o Paulo SP, Brazil."},{"name":"Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behavior, Department of Neurology, Centre of Expertise for Parkinson & Movement Disorders, Nijmegen GE The Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9804-353X","authenticated-orcid":false,"given":"Ariana Moura","family":"Cabral","sequence":"additional","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ndia, Faculdade de Engenharia El\u00e9trica, N\u00facleo de Inova\u00e7\u00e3o e Avalia\u00e7\u00e3o Tecnol\u00f3gica em Sa\u00fade, Uberl\u00e2ndia MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5689-6606","authenticated-orcid":false,"given":"Adriano de Oliveira","family":"Andrade","sequence":"additional","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ndia, Faculdade de Engenharia El\u00e9trica, N\u00facleo de Inova\u00e7\u00e3o e Avalia\u00e7\u00e3o Tecnol\u00f3gica em Sa\u00fade, Uberl\u00e2ndia MG, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,4,27]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1016\/S0140-6736(21)00218-X","article-title":"Parkinson's disease","volume":"397","author":"B R Bloem","year":"2021","journal-title":"Lancet"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1590\/0004-282x-anp-2021-0219","article-title":"Guidelines for Parkinson's disease treatment: consensus from the Movement Disorders Scientific Department of the Brazilian Academy of Neurology - motor symptoms","volume":"80","author":"R A Saba","year":"2022","journal-title":"Arq 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