{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T23:10:06Z","timestamp":1751843406167,"version":"3.41.0"},"reference-count":13,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T00:00:00Z","timestamp":1751760000000},"content-version":"vor","delay-in-days":96,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ortop (Sao Paulo)"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To compare the effect of combined spinal fusion (anteroposterior) on pulmonary function in patients with scoliosis secondary to Marfan syndrome versus neurofibromatosis type 1 (NF1) at long-term follow-up (&gt; 10 years).<\/jats:p><jats:p>Retrospective comparative study with nine patients, operated from March 1997 to December 2009, groups: Marfan syndrome versus NF1. Outcome measures were sex; age (at diagnosis and surgery); corrected height by wingspan; body mass index (BMI); duration of surgery (minutes); estimated blood loss (mL); last follow-up (years); pulmonary and implants related complications; pre- and postoperative Cobb angle of main thoracic curve and of thoracic kyphosis (T5 to T12); number of instrumented levels; absolute and percentage predicted values of forced vital capacity (FVC) and forced expiratory volume in 1\u2009second (FEV1). The data was processed in the IBM SPSS Statistics for Windows software (IBM Corp.), version 20.0, and the comparisons of means used the Student's t-test and analysis of variance (ANOVA), or the Mann-Whitney and Kruskal-Wallis\/Dunn tests, with a p-value of 0.05.<\/jats:p><jats:p>There was no difference in the absolute and predicted percentage values of pulmonary function, FVC and FEV1, and Cobb of the main thoracic curve between the groups, pre- and postoperatively (p\u2009&gt;\u20090.05). However, there was a significant reduction in the Cobb of the main thoracic curve in the Marfan syndrome group (74\u219246\u00b0, p\u2009&lt;\u20090.05).<\/jats:p><jats:p>There was no worsening of pulmonary function in patients who underwent the combined approach after a follow-up of more than 10 years, and there were no significant differences in the postoperative values of the pulmonary function test between the groups.<\/jats:p><jats:p>Level of evidence IV; case series.<\/jats:p>","DOI":"10.1055\/s-0045-1809340","type":"journal-article","created":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T22:32:19Z","timestamp":1751841139000},"page":"001-008","source":"Crossref","is-referenced-by-count":0,"title":["Long-Term Pulmonary Function after Combined Anteroposterior Spinal Fusion for Scoliosis in Neurofibromatosis Type 1 and Marfan Syndrome at a Mean Follow-Up of 13 Years"],"prefix":"10.1055","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6424-1490","authenticated-orcid":false,"given":"Jos\u00e9 Alberto Alves","family":"Oliveira","sequence":"additional","affiliation":[{"name":"School of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil"},{"name":"Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7000-9460","authenticated-orcid":false,"given":"Rog\u00e9rio dos Reis","family":"Visconti","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4832-3813","authenticated-orcid":false,"given":"Gustavo Borges Laurindo de","family":"Azevedo","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8337-7676","authenticated-orcid":false,"given":"Alderico Gir\u00e3o Campos de","family":"Barros","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9263-4216","authenticated-orcid":false,"given":"Luis E.","family":"Carelli","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3116-0253","authenticated-orcid":false,"given":"Jos\u00e9 Roberto Lapa e","family":"Silva","sequence":"additional","affiliation":[{"name":"School of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,7,6]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1097\/BSD.0b013e31824de6f1","article-title":"Surgical outcomes of scoliosis surgery in Marfan syndrome","volume":"27","author":"J Zenner","year":"2014","journal-title":"J Spinal Disord Tech"},{"issue":"10","key":"ref2","doi-asserted-by":"publisher","first-page":"3288","DOI":"10.1007\/s00586-016-4579-0","article-title":"Surgical treatment of scoliosis in Marfan syndrome: outcomes and complications","volume":"25","author":"J Qiao","year":"2016","journal-title":"Eur Spine J"},{"issue":"04","key":"ref3","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1302\/1863-2548.14.200076","article-title":"The correlation between spinal and chest wall deformities and pulmonary function in Marfan syndrome","volume":"14","author":"H Otremski","year":"2020","journal-title":"J Child Orthop"},{"issue":"10","key":"ref4","doi-asserted-by":"publisher","first-page":"6012","DOI":"10.21037\/jtd-21-1064","article-title":"Respiratory manifestations of Marfan syndrome: a narrative review","volume":"13","author":"M H Tun","year":"2021","journal-title":"J Thorac Dis"},{"issue":"01","key":"ref5","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1097\/BPO.0000000000001090","article-title":"Long-term Surgical Outcomes After Early Definitive Spinal Fusion for Early-onset Scoliosis With Neurofibromatosis Type 1 at Mean Follow-up of 14 Years","volume":"40","author":"R Tauchi","year":"2020","journal-title":"J Pediatr Orthop"},{"issue":"03","key":"ref6","doi-asserted-by":"publisher","first-page":"310","DOI":"10.3171\/spi.2002.97.3.0310","article-title":"Surgical treatment of spinal deformities associated with neurofibromatosis type 1. Report of 12 cases","volume":"97","author":"V Halmai","year":"2002","journal-title":"J Neurosurg"},{"issue":"03","key":"ref7","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1007\/s00586-020-06645-8","article-title":"Spinal fusion in pediatric patients with Marfan syndrome: a nationwide assessment on short-term outcomes and readmission risk","volume":"30","author":"M W Fields","year":"2021","journal-title":"Eur Spine J"},{"issue":"17","key":"ref8","doi-asserted-by":"publisher","first-page":"1815","DOI":"10.1097\/BRS.0b013e3181ab64e9","article-title":"Spine deformities in rare congenital syndromes: clinical issues","volume":"34","author":"R M Campbell Jr","year":"2009","journal-title":"Spine"},{"issue":"02","key":"ref9","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1183\/09031936.05.00034805","article-title":"Standardisation of spirometry","volume":"26","author":"M R Miller","year":"2005","journal-title":"Eur Respir J"},{"issue":"04","key":"ref10","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1002\/(SICI)1096-8628(19960424)62","article-title":"Revised diagnostic criteria for the Marfan syndrome","volume":"62","author":"A De Paepe","year":"1996","journal-title":"Am J Med Genet"},{"issue":"07","key":"ref11","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1136\/jmg.2009.072785","article-title":"The revised Ghent nosology for the Marfan syndrome","volume":"47","author":"B L Loeys","year":"2010","journal-title":"J Med Genet"},{"issue":"05","key":"ref12","doi-asserted-by":"publisher","first-page":"335","DOI":"10.3928\/01477447-20100329-20","article-title":"Research update and recent developments in the management of scoliosis in neurofibromatosis type 1","volume":"33","author":"Z Wang","year":"2010","journal-title":"Orthopedics"},{"issue":"04","key":"ref13","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1097\/BSD.0000000000001069","article-title":"Combined Anterior-Posterior Versus Posterior-only Spinal Fusion in Treating Dystrophic Neurofibromatosis Scoliosis With Modern Instrumentation: A Systematic Review and Meta-analysis","volume":"34","author":"F Jia","year":"2021","journal-title":"Clin Spine Surg"}],"container-title":["Revista Brasileira de Ortopedia"],"original-title":[],"language":"pt","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0045-1809340.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T22:32:19Z","timestamp":1751841139000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0045-1809340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":13,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2025,6,14]]},"published-print":{"date-parts":[[2025,4]]}},"alternative-id":["s00451809340"],"URL":"https:\/\/doi.org\/10.1055\/s-0045-1809340","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0102-3616","1982-4378"],"issn-type":[{"value":"0102-3616","type":"print"},{"value":"1982-4378","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]}}}