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This review proposes a practical classification of neurocutaneous syndromes based on their neurological manifestations, including neoplastic lesions, epilepsy, vascular abnormalities, and ataxia. In this narrative review, we examined original articles and reviews that explore neurocutaneous syndromes, published between January 2000 and July 2024. The figures are part of a personal collection of the authors. Early recognition of dermatological and neurological hallmarks can guide diagnosis and prompt timely evaluation and treatment. Therefore, a thorough understanding of neurocutaneous syndromes highlights the importance of integrated diagnostic strategies that combine neurological and dermatological assessments.<\/jats:p>","DOI":"10.1055\/s-0045-1809664","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T19:13:41Z","timestamp":1750878821000},"page":"001-014","source":"Crossref","is-referenced-by-count":1,"title":["A diagnostic approach to neurocutaneous syndromes"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8635-2338","authenticated-orcid":false,"given":"Sofia M\u00f4naco","family":"Gama","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6347-9413","authenticated-orcid":false,"given":"Jo\u00e3o Vitor 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