{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:35:57Z","timestamp":1760661357117,"version":"build-2065373602"},"reference-count":21,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In oral carcinoma patients classified as cN0, selective neck dissection (SND) and sentinel lymph node biopsy (SLNB) may be used to stage the neck with equivalent oncological results.<\/jats:p><jats:p>Compare the costs of SLNB and SND for oral squamous cell carcinoma.<\/jats:p><jats:p>Analysis of institutional cohort and Markov chain model simulation using populational data.<\/jats:p><jats:p>We included 84 patients submitted to transoral resection and SLNB or SND and patients submitted only to SND. The mean cost was R$4,943,67 for SLNB and R$ 11,005.49 for SND with significant differences in length of stay (one versus three days, p\u2009&lt;\u20090.001), operative time (92 versus 177\u2009minutes, p\u2009&lt;\u20090.001) and postoperative hospital visits in 60 days (two versus eight, p\u2009&lt;\u20090.001). For the simulation model, the probability of not finding the SLN ranged from 0.0% to 5.7% with 0.5% increments and the probability of occult neck metastasis ranged from 9.0% to 100.0% with 1% increments. The costs of SLNB increase progressively as the rate of occult neck metastasis increases. When this rate reaches 56%, the cost difference becomes not significant. With rates above 72%, SLNB becomes significantly more expensive than SND. Using a public database, we calculate a cost decrease ranging from 27.93% to 66.54% with SLNB adoption.<\/jats:p><jats:p>SLNB adoption may significantly decrease the costs associated with early-stage oral cancer treatment. It would allow more patients to be treated with the same number of resources now available.<\/jats:p>","DOI":"10.1055\/s-0045-1809906","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T23:31:27Z","timestamp":1760657487000},"page":"001-007","source":"Crossref","is-referenced-by-count":0,"title":["Cost Analysis of Sentinel Lymph Node Biopsy for Oral Tongue Squamous Cell Carcinoma: Institutional Cohort and Population-Based Simulation"],"prefix":"10.1055","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2319-7574","authenticated-orcid":false,"given":"Hugo Fontan","family":"K\u00f6hler","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otolaryngology, AC Camargo Cancer Center, S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8741-3278","authenticated-orcid":false,"given":"Genival Barbosa","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otolaryngology, AC Camargo Cancer Center, S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1995-6742","authenticated-orcid":false,"given":"Jos\u00e9 Guilherme","family":"Vartanian","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otolaryngology, AC Camargo Cancer Center, S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0481-156X","authenticated-orcid":false,"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery and Otolaryngology, AC Camargo Cancer Center, S\u00e3o Paulo, SP, Brazil"},{"name":"Department of Surgery, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, SP, 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