{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:48:47Z","timestamp":1782254927602,"version":"3.54.5"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T00:00:00Z","timestamp":1752796800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Obesity is a well-known risk factor for cardiovascular disease. Measurement of pericardial fat (PF) by multidetector computed tomography (MDCT) might have potential for early diagnosis and assessment of risk of coronary artery disease (CAD). Our study is the first study from India, wherein we have tried to find the association of PF with the severity of CAD.<\/jats:p>\n                  <jats:p>To evaluate the association of PF quantified by MDCT with the severity of CAD.<\/jats:p>\n                  <jats:p>This cross-sectional study was performed at a single-tertiary-care center over a period of 18 months, and included patients who referred for coronary computed tomography: (1) suspected case of CAD, (2) symptomatic patient with intermediate pretest probability of CAD, or uninterpretable electrocardiogram, or unable to exercise on stress test. Periprostatic fat volume (PFV) was quantified using semiautomated technique, for measuring the amount of fat during end-systolic phase. Patients who had evidence of CAD were considered \u201cCAD positive\u201d in this study.<\/jats:p>\n                  <jats:p>A total of 87 patients were enrolled in this study. However, 7 patients were excluded due to motion artifacts and 80 patients (females, 27.5%, and males, 72.5%; mean age, 49.30\u2009\u00b1\u200912.27 years) were eligible for this study. PFV ranged from 28 to 547\u2009mL, and the median value of PFV was around 100\u2009mL.<\/jats:p>\n                  <jats:p>Our study demonstrated a significant association between PF and age\/body mass index\/risk factors such as diabetes or family history. Higher PF was strongly associated with calcium score and severity of stenosis on computed tomography coronary angiography. Thus, PF is a risk predictor in subclinical CAD patients.<\/jats:p>","DOI":"10.1055\/s-0045-1810066","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T23:35:41Z","timestamp":1752881741000},"page":"326-333","source":"Crossref","is-referenced-by-count":0,"title":["Association of Pericardial Fat with Severity of Coronary Artery Disease"],"prefix":"10.1055","volume":"36","author":[{"given":"Sunil Kumar K.","family":"S.","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4088-1554","authenticated-orcid":false,"given":"Pankaj","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barun","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udit","family":"Chauhan","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,7,18]]},"reference":[{"issue":"21","key":"ref1","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1161\/01.CIR.97.21.2099","article-title":"American Heart Association call to action: obesity as a major risk factor for coronary heart disease","volume":"97","author":"R H Eckel","year":"1998","journal-title":"Circulation"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1758-5996-2-55","article-title":"Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: from diagnosis to treatment","volume":"2","author":"A Halpern","year":"2010","journal-title":"Diabetol Metab Syndr"},{"issue":"06","key":"ref3","doi-asserted-by":"crossref","first-page":"2548","DOI":"10.1210\/jc.2004-0395","article-title":"Adipose tissue as an endocrine organ","volume":"89","author":"E E Kershaw","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"07","key":"ref4","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1172\/JCI29069","article-title":"Inflammation and insulin resistance","volume":"116","author":"S E Shoelson","year":"2006","journal-title":"J Clin Invest"},{"issue":"20","key":"ref5","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1161\/01.CIR.0000099542.57313.C5","article-title":"Human epicardial adipose tissue is a source of inflammatory mediators","volume":"108","author":"T Mazurek","year":"2003","journal-title":"Circulation"},{"issue":"02","key":"ref6","first-page":"157","article-title":"The metabolic syndrome in a global perspective. 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