{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:48:47Z","timestamp":1782254927617,"version":"3.54.5"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Immunoglobulin G4-related mastitis (IgG4-RM) represents localized form of IgG4-related disease (IgG4-RD), an immune-driven condition marked by abnormal infiltration of plasma cells and raised IgG4 levels. Breast involvement is exceedingly rare and often misinterpreted as malignancy. We report a case of a 40-year-old woman presenting with right axillary lymphadenopathy and clinical suspicion of occult breast malignancy. Contrast-enhanced mammography (CEM) revealed multiple small, equal-density, microlobulated masses in both breasts, exhibiting moderate heterogeneous enhancement. The findings and pattern of involvement favored a secondary breast involvement rather than primary malignancy. 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography demonstrated FDG-avid lesions in the breasts, liver, and spleen, pointing toward systemic immune-mediated pathology. Core biopsy from the breast confirmed IgG4-RM. The patient responded extremely well to oral corticosteroids. This case highlights the diagnostic challenges of IgG4-RM and underscores the critical role of radiologic-pathologic correlation. To the best of our knowledge, this case is the first report in the literature to illustrate the CEM features of IgG4-RM, offering novel imaging insights into this underrecognized entity.<\/jats:p>","DOI":"10.1055\/s-0045-1811211","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T23:03:44Z","timestamp":1755212624000},"page":"412-416","source":"Crossref","is-referenced-by-count":0,"title":["Perplexing Case of IgG4-Related Mastitis: Hitherto Undescribed Contrast-Enhanced Mammography Features"],"prefix":"10.1055","volume":"36","author":[{"given":"Veenu","family":"Singla","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dollphy","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debajyoti","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghav","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5098-5707","authenticated-orcid":false,"given":"Rajender Kumar","family":"Basher","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddhant","family":"Khare","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s40792-019-0681-y","article-title":"Distinction of IgG4-related mastitis from breast cancer: a case report","volume":"5","author":"B Tsuda","year":"2019","journal-title":"Surg Case Rep"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ijscr.2017.06.012","article-title":"Immunoglobulin-G4 related mastitis: a case report","volume":"37","author":"E S Tan","year":"2017","journal-title":"Int J Surg Case 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sclerosing mastitis: expanding the morphological spectrum of IgG4 related diseases","volume":"47","author":"A Chougule","year":"2015","journal-title":"Pathology"},{"issue":"04","key":"ref10","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1148\/rg.2016150235","article-title":"Immunoglobulin G4 -related sclerosing mastitis: AIRP best cases in radiologic-pathologic correlation","volume":"36","author":"E Zalaquett","year":"2016","journal-title":"Radiographics"},{"issue":"07","key":"ref11","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1002\/art.39132","article-title":"International consensus guidance statement on the management and treatment of Igg4-related disease","volume":"67","author":"A Khosroshahi","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"623","DOI":"10.46497\/ArchRheumatol.2020.7567","article-title":"Immunoglobulin G4-related mastitis: an unusual case of recurrent breast 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