{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:01:58Z","timestamp":1788537718239,"version":"build-2803163510"},"reference-count":20,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Radiol Imaging"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The aim of this study was to compare the efficacy of various cardiac magnetic resonance imaging (MRI) parameters in assessing myocardial viability with positron emission tomography\u2013computed tomography (PET-CT) as the gold standard.<\/jats:p>\n                  <jats:p>This was a prospective analytical study comprising 28 adult patients with perfusion\/metabolism matched or mismatched defects in PET-CT. These patients were taken up for MR evaluation, mainly assessing end-diastolic wall thickness (EDWT), regional wall motion abnormalities, and late gadolinium enhancement (LGE) for infarcted tissue. EDWT was measured manually and using semiautomatic software, and means were calculated.<\/jats:p>\n                  <jats:p>Of 448 (28\u2009\u00d7\u200916) myocardial segments, 6% (n\u2009=\u200927) of the segments were considered not viable with matched defect, 56.5% (n\u2009=\u2009253) were normal, and 37.5% (n\u2009=\u2009168) were hibernating according to PET-CT. 51.1% (n\u2009=\u200986) of the hibernating segments showed no wall motion and 48% (n\u2009=\u200982) showed some wall motion, with a sensitivity of 66.03% (p\u2009&lt;\u20090.001). There is good concordance of motion abnormalities detected using tagging with LGE. LGE and EDWT showed good sensitivity, 91.7 and 89.5%, respectively, as compared with PET CT in identifying viable but hibernating myocardium.<\/jats:p>\n                  <jats:p>MRI parameter shows increased specificity and positive predictive value in identifying non-viable myocardium compared with PET\/CT. All parameters had good sensitivity in identifying hibernating myocardium but had significantly low specificities.<\/jats:p>\n                  <jats:p>Clinical relevance Cardiac MRI, when used in combination with PET CT, improves the sensitivity in identifying the viable but hibernating myocardium.<\/jats:p>","DOI":"10.1055\/s-0045-1811583","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T23:02:19Z","timestamp":1758322939000},"page":"366-373","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of Cardiac MR with PET CT in Evaluation of Myocardial Viability: Single-Center Experience"],"prefix":"10.1055","volume":"36","author":[{"given":"Md Y.","family":"Arafath","sequence":"additional","affiliation":[{"name":"Department of Radiology, Post Graduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uma","family":"Debi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Post Graduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1311-7203","authenticated-orcid":false,"given":"Manphool","family":"Singhal","sequence":"additional","affiliation":[{"name":"Department of Radiology, Post Graduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini","family":"Sood","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Post Graduate Institute of Medical Education & Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit Kumar","family":"Manoj","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Post Graduate Institute 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imaging compared with 201Tl SPECT imaging","volume":"232","author":"G K Lund","year":"2004","journal-title":"Radiology"},{"issue":"02","key":"ref7","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jacc.2006.08.047","article-title":"Diagnostic value of contrast-enhanced magnetic resonance imaging and single-photon emission computed tomography for detection of myocardial necrosis early after acute myocardial infarction","volume":"49","author":"T Ibrahim","year":"2007","journal-title":"J Am Coll Cardiol"},{"issue":"06","key":"ref8","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1067\/mnc.2001.119690","article-title":"The role of capillaries in determining coronary blood flow reserve: Implications for stress-induced reversible perfusion defects","volume":"8","author":"S Kaul","year":"2001","journal-title":"J Nucl 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Braunwald","year":"1986","journal-title":"J Am Coll Cardiol"},{"issue":"01","key":"ref12","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0002-8703(89)90685-6","article-title":"The hibernating myocardium","volume":"117","author":"S H Rahimtoola","year":"1989","journal-title":"Am Heart J"},{"issue":"09","key":"ref13","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1002\/clc.4960140903","article-title":"The stunned and hibernating myocardium: a brief review","volume":"14","author":"C R Conti","year":"1991","journal-title":"Clin Cardiol"},{"issue":"07","key":"ref14","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1007\/s00259-005-1779-y","article-title":"EANM\/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology","volume":"32","author":"B Hesse","year":"2005","journal-title":"Eur J Nucl Med Mol 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