{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:06:12Z","timestamp":1764720372511,"version":"3.46.0"},"reference-count":17,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asian J Neurosurg"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Neural tube defects (NTDs) are common congenital anomalies, with myelomeningocele (MMC) being the most severe form. Double-level MMC is exceedingly rare, with fewer than 60 cases reported worldwide and none from Southeast Asia. We report a 4-month-old male with two congenital swellings on his back, diagnosed as double MMC at the cervical and lumbar levels, along with hydrocephalus and Arnold\u2013Chiari malformation. Surgical management, including ventriculoperitoneal shunting and MMC repair, resulted in good outcomes. This case highlights the importance of early diagnosis, timely surgical intervention, and prenatal folic acid supplementation to reduce NTD risk in resource-limited settings.<\/jats:p>","DOI":"10.1055\/s-0045-1811607","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T23:02:49Z","timestamp":1757372569000},"page":"888-893","source":"Crossref","is-referenced-by-count":0,"title":["Successful Management of a Rare Case of Double Myelomeningocele in an Infant: A Case Report from Pakistan and Brief Review of Pathophysiology"],"prefix":"10.1055","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1602-2147","authenticated-orcid":false,"given":"Hammad","family":"Amjad","sequence":"additional","affiliation":[{"name":"Department of MBBS, Karachi Medical and Dental College, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1169-4507","authenticated-orcid":false,"given":"Mobeen","family":"Abid","sequence":"additional","affiliation":[{"name":"Department of MBBS, Karachi Medical and Dental College, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5522-5436","authenticated-orcid":false,"given":"Jahan","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7497-0132","authenticated-orcid":false,"given":"Areesha","family":"Hafeez","sequence":"additional","affiliation":[{"name":"Department of MBBS, Karachi Medical and Dental College, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5796-9132","authenticated-orcid":false,"given":"Shanzay","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of MBBS, Karachi Medical and Dental College, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6158-4803","authenticated-orcid":false,"given":"Syed Faisal","family":"Nadeem","sequence":"additional","affiliation":[{"name":"Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faizyab","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"issue":"01","key":"ref1","first-page":"52","article-title":"Factors affecting the outcomes in children post-myelomeningocoele repair in northeastern peninsular Malaysia","volume":"18","author":"B Idris","year":"2011","journal-title":"Malays J Med Sci"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"356","DOI":"10.17305\/bjbms.2008.2897","article-title":"Congenital malformations of the central nervous system: clinical approach","volume":"8","author":"F Hadzagi\u0107-Catibusi\u0107","year":"2008","journal-title":"Bosn J Basic Med Sci"},{"key":"ref3","first-page":"360","volume-title":"Neural tube defects","author":"D Doherty","year":"2014","edition":"2nd ed."},{"issue":"06","key":"ref4","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1227\/neu.0000000000002604","article-title":"Postnatal myelomeningocele repair in 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