{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T06:50:03Z","timestamp":1770706203628,"version":"3.49.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Dengue encephalitis is an uncommon neurological complication of dengue virus infection. In immunocompromised patients, such as solid organ transplant recipients, the clinical presentation may be atypical and nonspecific, posing significant diagnostic and therapeutic challenges. We report a clinical case and use it as a framework to discuss key considerations for suspicion of dengue encephalitis. Topics include optimal timing for clinical suspicion, essential differential diagnoses, and the most appropriate diagnostic strategies. Emphasis is placed on the correct interpretation of cerebrospinal fluid findings and recognition of subtle brain magnetic resonance imaging changes that may support the diagnosis. The discussion also reviews current evidence on dengue encephalitis in immunocompromised populations, highlighting implications for timely diagnosis and management in this vulnerable group.<\/jats:p>","DOI":"10.1055\/s-0045-1812888","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:05:36Z","timestamp":1770249936000},"page":"001-004","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic challenges in dengue encephalitis: subtle imaging findings and initially negative laboratory test in a kidney transplant recipient"],"prefix":"10.1055","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9955-7030","authenticated-orcid":false,"given":"Juan Sebasti\u00e1n S\u00e1nchez","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre, Porto Alegre RS, Brazil."},{"name":"Santa Casa de Miseric\u00f3ria de Porto Alegre, Porto Alegre RS, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0467-8585","authenticated-orcid":false,"given":"Vanessa Dantas de","family":"Andrade","sequence":"additional","affiliation":[{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre, Porto Alegre RS, Brazil."},{"name":"Santa Casa de Miseric\u00f3ria de Porto Alegre, Porto Alegre RS, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1315-7926","authenticated-orcid":false,"given":"Amanda Fernandes Klajn","family":"Mayc\u00e1","sequence":"additional","affiliation":[{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre, Porto Alegre RS, Brazil."},{"name":"Santa Casa de Miseric\u00f3ria de Porto Alegre, Porto Alegre RS, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4189-7339","authenticated-orcid":false,"given":"Carolina Matte","family":"Dagostini","sequence":"additional","affiliation":[{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre, Porto Alegre RS, Brazil."},{"name":"Santa Casa de Miseric\u00f3ria de Porto Alegre, Porto Alegre RS, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4131-4877","authenticated-orcid":false,"given":"Marcela Nataly Parra","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre, Porto Alegre RS, Brazil."},{"name":"Santa Casa de Miseric\u00f3ria de Porto Alegre, Porto Alegre RS, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4402-099X","authenticated-orcid":false,"given":"Marlise Ribeiro de","family":"Castro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre, Porto Alegre RS, 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