{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T01:18:48Z","timestamp":1765243128804,"version":"3.46.0"},"reference-count":32,"publisher":"Georg Thieme Verlag KG","issue":"11","license":[{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Migraine is a common neurological disorder associated with an increased risk of cardiovascular conditions, including arrhythmias. Although autonomic dysfunction is considered a key mechanism linking migraine and cardiac abnormalities, its impact during pain-free intervals remains unclear.<\/jats:p>\n                  <jats:p>To investigate the association between migraine and cardiac arrhythmias, focusing on the prevalence of premature ventricular contractions (PVCs) and autonomic dysfunction during pain-free periods.<\/jats:p>\n                  <jats:p>A total of 50 migraine patients and 51 age- and sex-matched healthy controls were enrolled in the present observational, cross-sectional study. All participants underwent 24-hour Holter monitoring, standard electrocardiographic and echocardiographic evaluation. The frequencies of PVCs, PR interval, QT interval (QTc), heart rate variability, and sinus tachycardia prevalence were compared between groups. Migraine-related disability was assessed using the Migraine Disability Assessment Scale (MIDAS) and the Headache Impact Test-6 (HIT-6).<\/jats:p>\n                  <jats:p>At least 1 PVC was detected in 40% of migraine patients, although no significant difference was observed compared with controls (p\u2009&gt;\u20090.05). However, migraine patients showed a significantly higher prevalence of sinus tachycardia (p\u2009&lt;\u20090.05). Additionally, a positive correlation was found between PVC burden and MIDAS scores, suggesting a potential link between migraine severity and arrhythmia risk. No significant differences were observed in QTc intervals or other major arrhythmic parameters.<\/jats:p>\n                  <jats:p>Migraine patients may exhibit increased sinus tachycardia and subtle electrocardiographic changes even during pain-free intervals, possibly reflecting underlying autonomic dysfunction.<\/jats:p>","DOI":"10.1055\/s-0045-1813242","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T01:07:32Z","timestamp":1765242452000},"page":"001-008","source":"Crossref","is-referenced-by-count":0,"title":["Premature ventricular complexes and migraine: insights from Holter monitoring during pain-free intervals"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1612-6359","authenticated-orcid":false,"given":"Serhat","family":"Kesriklioglu","sequence":"additional","affiliation":[{"name":"Necmettin Erbakan University, Faculty of Medicine, Department of Cardiology, Konya, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7649-5503","authenticated-orcid":false,"given":"Muhammed Fatih","family":"Kaleli","sequence":"additional","affiliation":[{"name":"Necmettin Erbakan University, Faculty of Medicine, Department of Cardiology, Konya, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5230-2180","authenticated-orcid":false,"given":"Yakup","family":"Alsancak","sequence":"additional","affiliation":[{"name":"Necmettin Erbakan University, Faculty of Medicine, Department of Cardiology, Konya, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9791-425X","authenticated-orcid":false,"given":"Aysenur","family":"Ince","sequence":"additional","affiliation":[{"name":"Kelkit State Hospital, Department of Neurology, Gumushane, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3011-1062","authenticated-orcid":false,"given":"Mustafa","family":"Altas","sequence":"additional","affiliation":[{"name":"Necmettin Erbakan University, Faculty of Medicine, Department of Neurology, Konya, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"issue":"30","key":"ref1","doi-asserted-by":"publisher","first-page":"2815","DOI":"10.1093\/eurheartj\/ehad363","article-title":"Migraine and cardiovascular disease: what cardiologists should know","volume":"44","author":"D N Kalkman","year":"2023","journal-title":"Eur Heart J"},{"issue":"13","key":"ref2","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.3390\/cells13131098","article-title":"Navigating the neurobiology of migraine: from pathways to potential therapies","volume":"13","author":"M 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