{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T00:02:16Z","timestamp":1766448136372,"version":"3.48.0"},"reference-count":30,"publisher":"Georg Thieme Verlag KG","issue":"05","license":[{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":82,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ortop (Sao Paulo)"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>To evaluate the role of arterial blood gas (ABG) parameters in predicting adverse in-hospital outcomes among patients with isolated diaphyseal femur fractures.<\/jats:p>\n                  <jats:p>A retrospective study was conducted at a tertiary care hospital between April 2020 and June 2021. Patients aged 18 to 70 years of both sexes with isolated diaphyseal femur fractures were included. The ABG parameters were assessed upon admission and 24\u2009hours postadmission. Their association with systemic complications, intensive care unit admission, and length of hospital stay was evaluated.<\/jats:p>\n                  <jats:p>The study included 55 patients with a mean age of 53.8 years. The ABG parameters upon admission and at 24\u2009hours were significantly associated with adverse outcomes, specifically pH\u2009&lt;\u20097.35, bicarbonate (HCO3\n                  \u2212)\u2009&lt;\u200922\u2009mmol\/L, partial pressure of carbon dioxide (PCO2)\u2009&lt;\u200935\u2009mmHg, partial pressure of oxygen (PO2)\u2009&lt;\u200983\u2009mmHg, and lactate\u2009&gt;\u20091.8\u2009mmol\/L. Elevated lactate levels upon admission were additionally correlated with prolonged hospital stay and systemic arterial hypertension.<\/jats:p>\n                  <jats:p>The ABG parameters assessed upon admission and 24\u2009hours postadmission serve as early predictors of adverse outcomes in patients with isolated diaphyseal femur fractures. These findings suggest that ABG analysis may be a valuable tool in guiding the clinical management of such patients.<\/jats:p>","DOI":"10.1055\/s-0045-1814127","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T23:58:29Z","timestamp":1766447909000},"page":"001-011","source":"Crossref","is-referenced-by-count":0,"title":["Does Arterial Blood Gas Analysis Predict an Adverse Course in Patients Admitted with Isolated Diaphyseal Femur Fractures?"],"prefix":"10.1055","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7357-3542","authenticated-orcid":false,"given":"D.","family":"Sidharth","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Shri Sathya Sai Medical College and Research Institute, Tamilnadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3501-2776","authenticated-orcid":false,"given":"Thatchinamoorthy","family":"Santhamoorthy","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Indira Gandhi Government General Hospital and Postgraduate Institute, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1374-6466","authenticated-orcid":false,"given":"Anish Anto","family":"Xavier","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Indira Gandhi Government General Hospital and Postgraduate Institute, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2799-4549","authenticated-orcid":false,"given":"Lalithambigai","family":"Chellamuthu","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9340-7317","authenticated-orcid":false,"given":"S.","family":"Ahilan","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Sri Laksminarayana Institute of Medical Sciences, Puducherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1136\/injuryprev-2015-041616","article-title":"The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013","volume":"22","author":"J A Haagsma","year":"2016","journal-title":"Inj Prev"},{"issue":"06","key":"ref2","doi-asserted-by":"publisher","first-page":"e0252673","DOI":"10.1371\/journal.pone.0252673","article-title":"Long-term medical and productivity costs of severe trauma: Results from a prospective cohort study","volume":"16","author":"M Van der Vlegel","year":"2021","journal-title":"PLoS One"},{"issue":"05","key":"ref3","doi-asserted-by":"publisher","first-page":"e1240","DOI":"10.1002\/hsr2.1240","article-title":"Road traffic accidental injuries and deaths: A neglected global health issue","volume":"6","author":"S K Ahmed","year":"2023","journal-title":"Health Sci Rep"},{"issue":"01","key":"ref4","doi-asserted-by":"publisher","first-page":"220","DOI":"10.3349\/ymj.2015.56.1.220","article-title":"Epidemiology of trauma patients and analysis of 268 mortality cases: trends of a single center in Korea","volume":"56","author":"C S Byun","year":"2015","journal-title":"Yonsei Med J"},{"issue":"03","key":"ref5","doi-asserted-by":"publisher","first-page":"558","DOI":"10.4103\/2249-4863.197279","article-title":"Profile of trauma patients in the emergency department of a tertiary care hospital in South India","volume":"5","author":"K P Abhilash","year":"2016","journal-title":"J Family Med Prim Care"},{"issue":"10","key":"ref6","doi-asserted-by":"publisher","first-page":"3416","DOI":"10.1016\/j.injury.2022.08.053","article-title":"Femur fractures and hemorrhagic shock: Implications for point of injury treatment","volume":"53","author":"I Y Mitchnik","year":"2022","journal-title":"Injury"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"27","DOI":"10.2147\/ORR.S340532","article-title":"Risks in the Management of Polytrauma Patients: Clinical Insights","volume":"15","author":"K P Iyengar","year":"2023","journal-title":"Orthop Res Rev"},{"issue":"07","key":"ref8","doi-asserted-by":"publisher","first-page":"110822","DOI":"10.1016\/j.injury.2023.05.053","article-title":"Femoral shaft fractures in eldery patients - 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