{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T09:55:40Z","timestamp":1769421340657,"version":"3.49.0"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"12","license":[{"start":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T00:00:00Z","timestamp":1769299200000},"content-version":"vor","delay-in-days":55,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Sir Isaac Newton is widely regarded as one of the greatest scientific minds in history, with seminal contributions across mathematics, physics\u2014particularly optics\u2014and the formulation of the law of universal gravitation. Less well known, however, is his extraordinary and rarely recognized contribution to the field of neurology: the early conceptualization of fiber decussation within the optic chiasm. Through his studies on light and vision, Newton proposed that optic nerve fibers cross at the chiasm\u2014a hypothesis that would later be anatomically confirmed and provided the basis for understanding the classic patterns of visual field deficits.<\/jats:p>","DOI":"10.1055\/s-0045-1814373","type":"journal-article","created":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T23:36:25Z","timestamp":1769384185000},"page":"001-003","source":"Crossref","is-referenced-by-count":0,"title":["Isaac Newton's description of the optic chiasm"],"prefix":"10.1055","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7568-0897","authenticated-orcid":false,"given":"Caio C. D.","family":"Disserol","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Medicina Interna, Servi\u00e7o de Neurologia, Curitiba PR, Brazil."},{"name":"Instituto de Neurologia de Curitiba, Curitiba PR, Brazil."},{"name":"Hospital Israelita Albert Einstein, Instituto do C\u00e9rebro, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7041-3255","authenticated-orcid":false,"given":"Mario T.","family":"Sato","sequence":"additional","affiliation":[{"name":"Instituto de Neurologia de Curitiba, Curitiba PR, Brazil."},{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Medicina Interna, Servi\u00e7o de Oftalmologia, Curitiba PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5100-042X","authenticated-orcid":false,"given":"Yago","family":"Alfaro","sequence":"additional","affiliation":[{"name":"Instituto de Neurologia de Curitiba, Curitiba PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4045-1178","authenticated-orcid":false,"given":"H\u00e9lio A. G.","family":"Teive","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Departamento de Medicina Interna, Servi\u00e7o de Neurologia, Curitiba PR, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,25]]},"reference":[{"issue":"6511","key":"ref1","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1136\/bmj.291.6511.1779","article-title":"Isaac Newton","volume":"291","author":"A Storr","year":"1985","journal-title":"Br Med J (Clin Res Ed)"},{"issue":"2039","key":"ref2","doi-asserted-by":"publisher","first-page":"2014213","DOI":"10.1098\/rsta.2014.0213","article-title":"Newton shows the light: a commentary on Newton (1672) \u2018A letter \u2026 containing his new theory about light and colours\u2026\u2019","volume":"373","author":"P Fara","year":"2015","journal-title":"Philos Trans A Math Phys Eng 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solitary endeavours\u201d of Isaac Newton, 1642-1727","volume":"46","author":"R J Mann","year":"1971","journal-title":"Mayo Clin Proc"},{"issue":"01","key":"ref11","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1001\/jama.222.1.72","article-title":"Sir Isaac Newton","volume":"222","author":"R A Kyle","year":"1972","journal-title":"JAMA"},{"issue":"01","key":"ref12","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1111\/j.1464-410X.2005.05242.x","article-title":"Celestial bodies and urinary stones: Isaac Newton (1641-1727)\u2013health and urological problems","volume":"95","author":"E Ostad","year":"2005","journal-title":"BJU Int"},{"key":"ref13","volume-title":"Opticks or, a Treatise of the Reflections, Refractions, Inflections and Colours of Light","author":"I Newton","year":"1952"},{"issue":"11","key":"ref14","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1007\/s00381-017-3564-1","article-title":"The history of optic chiasm from antiquity to the twentieth century","volume":"33","author":"C F Costea","year":"2017","journal-title":"Childs Nerv Syst"},{"key":"ref15","first-page":"93","volume-title":"The optic nerve","author":"A F Haerer","year":"1992","edition":"5th edition."}],"container-title":["Arquivos de 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